Zobrazeno 1 - 10
of 671
pro vyhledávání: '"Infectious Diseases/Neglected Tropical Diseases"'
Publikováno v:
Scopus-Elsevier
PLoS ONE, Vol 5, Iss 9, p e12557 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12557 (2010)
PLoS ONE
Malaria remains one of the world's greatest killers and a vaccine is urgently required. There are no established correlates of protection against malaria either for natural immunity to the disease or for immunity conferred by candidate malaria vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f369e3d7cd93d76dcb8a904fec093773
https://doi.org/10.1371/journal.pone.0012557
https://doi.org/10.1371/journal.pone.0012557
Autor:
R Chandra, Quique Bassat, Janice Culpepper, François Nosten, J Nájera, Dyann F. Wirth, J Pottage, Christopher V. Plowe, Ramanan Laxminarayan, Pascal Ringwald, C Marzetta, Steve A. Ward, Pedro L. Alonso, Peter G. Kremsner, MacArthur, Mark M. Fukuda, R. Sinden, Theonest K. Mutabingwa, Ivo Mueller, Alan J. Magill, Y Yuthavong, Jessica Milman, Nicholas J. White, Thomas E. Wellems, Regina Rabinovich, Abdoulaye Djimde, Rhoel R. Dinglasan, C Ohrt, Dennis Shanks, Ric N. Price, Stephan Duparc, Fred Binka, K Duncan, Marcel Tanner, H Vial, Robert D. Newman, Solomon Nwaka, Shunmay Yeung, A. Serazin, Thomas G. Brewer, Timothy N. C. Wells, Myaing M. Nyunt
Publikováno v:
PLoS Medicine, Vol 8, Iss 1, p e1000402 (2011)
PLoS Medicine
PLoS Medicine
The Malaria Eradication Research Agenda (malERA) Consultative Group on Drugs present a research and development agenda to ensure that appropriate drugs are available for use in malaria eradication.
Antimalarial drugs will be essential tools at a
Antimalarial drugs will be essential tools at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d673793be3da09f6c3b8ca74aee795ee
https://ora.ox.ac.uk/objects/uuid:e4536797-d8a2-445b-b4af-7f362f67c216
https://ora.ox.ac.uk/objects/uuid:e4536797-d8a2-445b-b4af-7f362f67c216
Autor:
Walker, RG, Thomson, G, Malone, K, Nowicki, MW, Brown, E, Blake, DG, Turner, NJ, Walkinshaw, MD, Grant, KM, Mottram, JC, Kita, K
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1033 (2011)
PLoS Neglected Tropical Diseases
Walker, R G, Thomson, G, Malone, K, Nowicki, M W, Brown, E, Blake, D G, Turner, N J, Walkinshaw, M D, Grant, K M & Mottram, J C 2011, ' High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase ', PLoS Neglected Tropical Diseases, vol. 5, no. 4, e1033, pp.-. https://doi.org/10.1371/journal.pntd.0001033
PLoS Neglected Tropical Diseases
Walker, R G, Thomson, G, Malone, K, Nowicki, M W, Brown, E, Blake, D G, Turner, N J, Walkinshaw, M D, Grant, K M & Mottram, J C 2011, ' High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase ', PLoS Neglected Tropical Diseases, vol. 5, no. 4, e1033, pp.-. https://doi.org/10.1371/journal.pntd.0001033
Background Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4a59d8a81dce37c29a9e8c905839f0
https://ora.ox.ac.uk/objects/uuid:b7ac0f17-98da-41fb-a2d5-8f53ae85b653
https://ora.ox.ac.uk/objects/uuid:b7ac0f17-98da-41fb-a2d5-8f53ae85b653
Autor:
Sharon J. Peacock, Vanaporn Wuthiekanun, Gumphol Wongsuvan, Narisara Chantratita, Direk Limmathurotsakul, Nicholas P. J. Day, Premjit Amornchai
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e694 (2010)
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e694 (2010)
Background Melioidosis is a frequently fatal infectious disease caused by the soil dwelling Gram-negative bacterium Burkholderia pseudomallei. Environmental sampling is important to identify geographical distribution of the organism and related risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9c418e5c2b66989e6ed0de51c0b987
https://doi.org/10.1371/journal.pntd.0000694
https://doi.org/10.1371/journal.pntd.0000694
Autor:
Ly-Mee Yu, Andrew J. Pollard, Laurent Audry, Sharon M. Brookes, David A. Warrell, François-Xavier Meslin, Judith Phipps, Linda Diggle, Richard Moxon, Anthony R. Fooks, Hervé Bourhy, Jonathan J Deeks, Mary J. Warrell, Anna Riddell
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 2, Iss 4, p e224 (2008)
PLoS Neglected Tropical Diseases, Vol 2, Iss 4, p e224 (2008)
Background The need for economical rabies post-exposure prophylaxis (PEP) is increasing in developing countries. Implementation of the two currently approved economical intradermal (ID) vaccine regimens is restricted due to confusion over different v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9756b3a2e8aa962da001cae686c4884c
https://ora.ox.ac.uk/objects/uuid:5a875ee1-11c9-46eb-9571-af2bb1f3fbd1
https://ora.ox.ac.uk/objects/uuid:5a875ee1-11c9-46eb-9571-af2bb1f3fbd1
Autor:
Axel Kroeger, Didye Ruiz, Susana Vázquez, Roger Gaczkowski, Shamala Devi Sekaran, Eva Harris, Elci Villegas, Eric Martinez, María G. Guzmán, Iris Villalobos, Thomas Jaenisch, Juan Carlos Mercado, Prisca Susan A. Leano, Angel Balmaseda, Herminia Benduzu, Vo Thi Ty Hang, Sutee Yoksan, Efren Dimano, Jeremy Farrar, Cameron P. Simmons
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 8 (2010)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Early diagnosis of dengue can assist patient triage and management and prevent unnecessary treatments and interventions. Commercially available assays that detect the dengue virus protein NS1 in the plasma/serum of patients offers the poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4514eaf09bb5859399643b65a31ba476
https://ora.ox.ac.uk/objects/uuid:28426e49-0b06-4df3-baa2-44ae14ac1b26
https://ora.ox.ac.uk/objects/uuid:28426e49-0b06-4df3-baa2-44ae14ac1b26
Autor:
Adrian J. Wolstenholme, Debra J. Woods, Sally M. Williamson, David B. Sattelle, Alan P. Robertson, Richard J. Martin, Tracey Williams, Laurence A. Brown
Publikováno v:
PLoS Pathogens
Williamson, S M, Robertson, A P, Brown, L, Williams, T, Woods, D J, Martin, R J, Sattelle, D B & Wolstenholme, A 2009, ' The nicotinic acetylcholine receptors of the parasitic nematode ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits ', PLoS Pathogens, vol. 5, no. 7, pp. e1000517 . https://doi.org/10.1371/journal.ppat.1000517
PLoS Pathogens, Vol 5, Iss 7, p e1000517 (2009)
Williamson, S M, Robertson, A P, Brown, L, Williams, T, Woods, D J, Martin, R J, Sattelle, D B & Wolstenholme, A 2009, ' The nicotinic acetylcholine receptors of the parasitic nematode ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits ', PLoS Pathogens, vol. 5, no. 7, pp. e1000517 . https://doi.org/10.1371/journal.ppat.1000517
PLoS Pathogens, Vol 5, Iss 7, p e1000517 (2009)
Parasitic nematodes are of medical and veterinary importance, adversely affecting human health and animal welfare. Ascaris suum is a gastrointestinal parasite of pigs; in addition to its veterinary significance it is a good model of the human parasit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ff545f978b9dfb633bd3f358fc15cf
https://doi.org/10.1371/journal.ppat.1000517
https://doi.org/10.1371/journal.ppat.1000517
Autor:
Alonso, PL, Eubank, S, Ghani, A, Hay, SI, Sinden, R, Smith, D, Smith, TA, Tanner, M, White, L, Modeling, MCG
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 8, Iss 1, p e1000403 (2011)
PLoS Medicine, Vol 8, Iss 1, p e1000403 (2011)
The Malaria Eradication Research Agenda (malERA) Consultative Group on Modeling outline a research and development agenda to ensure that appropriate models are in place to guide malaria elimination.
Malaria modeling can inform policy and guide r
Malaria modeling can inform policy and guide r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91617ae3d40d1ce11f742447f50c31a8
https://ora.ox.ac.uk/objects/uuid:7877bb3c-7cd2-402f-b207-997480733b6e
https://ora.ox.ac.uk/objects/uuid:7877bb3c-7cd2-402f-b207-997480733b6e
Autor:
Paolo S. Ocampo, George J. Armelagos, Nigel J. Saunders, Kristin N. Harper, Michael S. Silverman, Allan Pillay, Robert W. George, Shelly Bolotin, Bret Steiner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 1, p e148 (2008)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Since the first recorded epidemic of syphilis in 1495, controversy has surrounded the origins of the bacterium Treponema pallidum subsp. pallidum and its relationship to the pathogens responsible for the other treponemal diseases: yaws, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77896c34db80cd51fc98b669c0004d45
https://doi.org/10.1371/journal.pntd.0000148
https://doi.org/10.1371/journal.pntd.0000148
Autor:
Moreno, Edgardo, Dozot, Marie, Poncet, Sandrine, Nicolas, Cécile, Copin, Richard, Bouraoui, Houda, Mazé, Alain, Deutscher, Josef, De Bolle, Xavier, Letesson, Jean-Jacques
Publikováno v:
Plos One 9 (5), e12679. (2010)
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (9), pp.e12679. ⟨10.1371/journal.pone.0012679⟩
Dozot, M, Nicolas, C, Copin, R, De Bolle, X, Letesson, J-J, Poncet, S, Bouraoui, H, Mazé, A & Deutscher, J 2010, ' Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen brucella melitensis ', PLoS ONE, vol. 5, no. 9, pp. 1-16 . https://doi.org/10.1371/journal.pone.0012679
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (9), pp.e12679. ⟨10.1371/journal.pone.0012679⟩
Dozot, M, Nicolas, C, Copin, R, De Bolle, X, Letesson, J-J, Poncet, S, Bouraoui, H, Mazé, A & Deutscher, J 2010, ' Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen brucella melitensis ', PLoS ONE, vol. 5, no. 9, pp. 1-16 . https://doi.org/10.1371/journal.pone.0012679
BackgroundIn many bacteria, the phosphotransferase system (PTS) is a key player in the regulation of the assimilation of alternative carbon sources notably through catabolic repression. The intracellular pathogens Brucella spp. possess four PTS prote