Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Inessa, Cohen"'
Autor:
Allyson Derry, Yvette Strong, Davia Schioppo, Joni Cotter, Geisa Wilkins, Laura Siqueiros, Andrea Ouyang, Kathleen Hulseman, Joseph Petrosino, Lorrin Liang, Megan Stevenson, Tiffany Aguilera, Alexandria Soto, Katherine Meurer, Alison Herman, Inessa Cohen, Guido Falcone, Erin Longbrake, Cassius Ochoa Chaar, Kelly Anastasio, Michael Murray
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101752- (2024)
Externí odkaz:
https://doaj.org/article/888c1e8506234fb8948f178b31de3cf3
Autor:
Avraham Unterman, Tomokazu S. Sumida, Nima Nouri, Xiting Yan, Amy Y. Zhao, Victor Gasque, Jonas C. Schupp, Hiromitsu Asashima, Yunqing Liu, Carlos Cosme, Wenxuan Deng, Ming Chen, Micha Sam Brickman Raredon, Kenneth B. Hoehn, Guilin Wang, Zuoheng Wang, Giuseppe DeIuliis, Neal G. Ravindra, Ningshan Li, Christopher Castaldi, Patrick Wong, John Fournier, Santos Bermejo, Lokesh Sharma, Arnau Casanovas-Massana, Chantal B. F. Vogels, Anne L. Wyllie, Nathan D. Grubaugh, Anthony Melillo, Hailong Meng, Yan Stein, Maksym Minasyan, Subhasis Mohanty, William E. Ruff, Inessa Cohen, Khadir Raddassi, The Yale IMPACT Research Team, Laura E. Niklason, Albert I. Ko, Ruth R. Montgomery, Shelli F. Farhadian, Akiko Iwasaki, Albert C. Shaw, David van Dijk, Hongyu Zhao, Steven H. Kleinstein, David A. Hafler, Naftali Kaminski, Charles S. Dela Cruz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
SARS-CoV-2 infection can lead to progressive pathology in patients with COVID-19, but information for this disease progression is sparse. Here the authors use multi-omics approach to profile the immune responses of patients, assessing immune repertoi
Externí odkaz:
https://doaj.org/article/071dfec07b41418ab54ed9c36dc0d83e
Autor:
Hiromitsu Asashima, Pierre-Paul Axisa, Thi Hong Giang Pham, Erin E. Longbrake, William E. Ruff, Nikhil Lele, Inessa Cohen, Khadir Raddassi, Tomokazu S. Sumida, David A. Hafler
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
B cell depletion in patients with relapsing-remitting multiple sclerosis (RRMS) markedly prevents new MRI-detected lesions and disease activity, suggesting the hypothesis that altered B cell function leads to the activation of T cells driving disease
Externí odkaz:
https://doaj.org/article/0c9d8420a9fe4098b16d60ae27757205
Publikováno v:
Transl Res
Immunomodulatory medications are a mainstay of treatment for autoimmune diseases and malignancies. In addition to their direct effects on immune cells, these medications also impact the gut microbiota. Drug-induced shifts in commensal microbes can le
Autor:
Hiromitsu Asashima, Subhasis Mohanty, Michela Comi, William E. Ruff, Kenneth B. Hoehn, Patrick Wong, Jon Klein, Carolina Lucas, Inessa Cohen, Sarah Coffey, Nikhil Lele, Leissa Greta, Khadir Raddassi, Omkar Chaudhary, Avraham Unterman, Brinda Emu, Steven H. Kleinstein, Ruth R. Montgomery, Akiko Iwasaki, Charles S. Dela Cruz, Naftali Kaminski, Albert C. Shaw, David A. Hafler, Tomokazu S. Sumida
Publikováno v:
Cell Reports. 42:111895
Autor:
Hiromitsu, Asashima, Subhasis, Mohanty, Michela, Comi, William E, Ruff, Kenneth B, Hoehn, Patrick, Wong, Jon, Klein, Carolina, Lucas, Inessa, Cohen, Sarah, Coffey, Nikhil, Lele, Leissa, Greta, Khadir, Raddassi, Omkar, Chaudhary, Avraham, Unterman, Brinda, Emu, Steven H, Kleinstein, Ruth R, Montgomery, Akiko, Iwasaki, Charles S, Dela Cruz, Naftali, Kaminski, Albert C, Shaw, David A, Hafler, Tomokazu S, Sumida
Publikováno v:
Cell reports.
T cell-B cell interaction is the key immune response to protect the host from severe viral infection. However, how T cells support B cells to exert protective humoral immunity in humans is not well understood. Here, we use COVID-19 as a model of acut
Autor:
Hiromitsu Asashima, Pierre-Paul Axisa, Thi Hong Giang Pham, Erin E. Longbrake, William E. Ruff, Nikhil Lele, Inessa Cohen, Khadir Raddassi, Tomokazu S. Sumida, David A. Hafler
Publikováno v:
The Journal of clinical investigation. 132(20)
B cell depletion in patients with relapsing-remitting multiple sclerosis (RRMS) markedly prevents new MRI-detected lesions and disease activity, suggesting the hypothesis that altered B cell function leads to the activation of T cells driving disease
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
PTEN is a tumor suppressor that is highly mutated in a variety of human cancers. Recent studies have suggested a link between PTEN loss and deficiency in the non-homologous end-joining (NHEJ) pathway of DNA double strand break (DSB) repair. As a mean
Autor:
William Ruff, Brinda Emu, Ruth R. Montgomery, Tomokazu Sumida, Albert C. Shaw, Akiko Iwasaki, Inessa Cohen, Charles S. Dela Cruz, Subhasis Mohanty, David A. Hafler, Avraham Unterman, Omkar Chaudhary, Kenneth B. Hoehn, Sarah Coffey, Michela Comi, Naftali Kaminski, Khadir Raddassi, Steven H. Kleinstein, Hiromitsu Asashima, Patrick Wong
SummaryA dysregulated immune response against coronavirus-2 (SARS-CoV-2) plays a critical role in the outcome of patients with coronavirus disease 2019 (COVID-19). A significant increase in circulating plasmablasts is characteristic of COVID-19 thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c021adc841424aec610f4ffd8395857
https://doi.org/10.1101/2021.03.13.21253527
https://doi.org/10.1101/2021.03.13.21253527
Autor:
Elle Levit, Inessa Cohen, Megan Dahl, Keith Edwards, Bianca Weinstock-Guttman, Toshinari Ishikawa, Katelyn Kavak, Victoria Leavitt, Katie Nelson, Kaho Onomichi, Amit Bar-Or, Christopher Perrone, Claire Riley, Shruthi Venkatesh, Philip L. De Jager, Zongqi Xia, Erin E. Longbrake
Publikováno v:
Multiple Sclerosis and Related Disorders
Objective To quantify changes in psychological wellbeing and physical function as reported by people with neurological inflammatory disease (PwNID) during the COVID-19 pandemic. Methods 1134 PwNID and 868 control participants were recruited through f