Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ines Wilkening"'
Autor:
Jo Vandesompele, Peter Nürnberg, Shantanu Banerji, Lukas C. Heukamp, Stefanie Heynck, Matthias Fischer, Daniel Rauh, Sylvie Lantuejoul, Ingelore Baessmann, Holger Moch, Matthew Meyerson, Reinhard Büttner, Kwon-Sik Park, Ines Wilkening, Steinar Solberg, Stefan A. Haas, Egber Smit, Dennis Plenker, Zoe Wainer, Prudence A. Russell, Ilona Dahmen, William Pao, Erik Thunnissen, C. Ligorio, Bram De Wilde, Paul K. Brindle, Diana Böhm, Vito Michele Fazio, Vincenzo Di Cerbo, Benjamin Solomon, Stefania Damiani, Walburga Engel-Riedel, Erich Stoelben, Corinna Ludwig, Hannie Sietsma, Daniëlle A M Heideman, Jürgen Wolf, Thomas Muley, Elisabeth Brambilla, Ruping Sun, Wim Timens, Jay Shendure, Laura Pasqualucci, Kristian Cibulskis, Julien Sage, Gavin M. Wright, Mirjam Koker, Pierre Validire, Danila Seidel, Johannes M. Heuckmann, Harry J.M. Groen, Christian Becker, Philippe Lorimier, Peter J.F. Snijders, Sven Perner, Michael Brockmann, Xin Lu, Franziska Gabler, Scott L. Carter, Marius Lund-Iversen, Lucia Anna Muscarella, Jörg Sänger, Benjamin Besse, Hans Ulrich Schildhaus, Frauke Leenders, John K. Field, Odd Terje Brustugun, Christian Brambilla, Philipp A. Schnabel, Sascha Ansén, Christian Grütter, Michael Hallek, Gad Getz, Yuan Chen, Roopika Menon, Roman K. Thomas, Joachim H. Clement, Janine Altmüller, Martin L. Sos, Hans Hoffmann, Peter M. Schneider, Julie George, Christian Müller, Iver Petersen, Federico Cappuzzo, Lawryn H. Kasper, Robert Schneider, Martin Peifer, Lynnette Fernandez-Cuesta, Jean-Charles Soria, Alex Soltermann, Thomas Zander, Walter Weder
Publikováno v:
Nature Genetics
Nature Genetics, 44(10), 1104-1110. Nature Publishing Group
Peifer, M, Fernandez-Cuesta, L, Sos, M L, George, J, Seidel, D, Kasper, L H, Plenker, D, Leenders, F, Sun, R, Zander, T, Menon, R, Koker, M, Dahmen, I, Muller, C, Di Cerbo, V, Schildhaus, H U, Altmuller, J, Baessmann, I, Becker, C, de Wilde, B, Vandesompele, J, Bohm, D, Ansen, S, Gabler, F, Wilkening, I, Heynck, S, Heuckmann, J M, Lu, X, Carter, S L, Cibulskis, K, Banerji, S, Getz, G, Park, K S, Rauh, D, Grutter, C, Fischer, M, Pasqualucci, L, Wright, G, Wainer, Z, Russell, P, Petersen, I, Chen, Y, Stoelben, E, Ludwig, C, Schnabel, P, Hoffmann, H, Muley, T, Brockmann, M, Engel-Riedel, W, Muscarella, L A, Fazio, V M, Groen, H, Timens, W, Sietsma, H, Thunnissen, F B J M, Smit, E F, Heideman, D A M, Snijders, P J F, Cappuzzo, F, Ligorio, C, Damiani, S, Field, J, Solberg, S, Brustugun, O T, Lund-Iversen, M, Sanger, J, Clement, J H, Soltermann, A, Moch, H, Weder, W, Solomon, B, Soria, J C, Validire, P, Besse, B, Brambilla, E, Brambilla, C, Lantuejoul, S, Lorimier, P, Schneider, P M, Hallek, M, Pao, W, Meyerson, M, Sage, J, Shendure, J, Schneider, R, Buttner, R, Wolf, J, Nurnberg, P, Perner, S, Heukamp, L C, Brindle, P K, de Haas, S & Thomas, R K 2012, ' Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer ', Nature Genetics, vol. 44, no. 10, pp. 1104-1110 . https://doi.org/10.1038/ng.2396
Nature Genetics, 44(10), 1104-+. Nature Publishing Group
Nature Genetics; Vol 44
Nature Genetics, 44(10), 1104-1110. Nature Publishing Group
Peifer, M, Fernandez-Cuesta, L, Sos, M L, George, J, Seidel, D, Kasper, L H, Plenker, D, Leenders, F, Sun, R, Zander, T, Menon, R, Koker, M, Dahmen, I, Muller, C, Di Cerbo, V, Schildhaus, H U, Altmuller, J, Baessmann, I, Becker, C, de Wilde, B, Vandesompele, J, Bohm, D, Ansen, S, Gabler, F, Wilkening, I, Heynck, S, Heuckmann, J M, Lu, X, Carter, S L, Cibulskis, K, Banerji, S, Getz, G, Park, K S, Rauh, D, Grutter, C, Fischer, M, Pasqualucci, L, Wright, G, Wainer, Z, Russell, P, Petersen, I, Chen, Y, Stoelben, E, Ludwig, C, Schnabel, P, Hoffmann, H, Muley, T, Brockmann, M, Engel-Riedel, W, Muscarella, L A, Fazio, V M, Groen, H, Timens, W, Sietsma, H, Thunnissen, F B J M, Smit, E F, Heideman, D A M, Snijders, P J F, Cappuzzo, F, Ligorio, C, Damiani, S, Field, J, Solberg, S, Brustugun, O T, Lund-Iversen, M, Sanger, J, Clement, J H, Soltermann, A, Moch, H, Weder, W, Solomon, B, Soria, J C, Validire, P, Besse, B, Brambilla, E, Brambilla, C, Lantuejoul, S, Lorimier, P, Schneider, P M, Hallek, M, Pao, W, Meyerson, M, Sage, J, Shendure, J, Schneider, R, Buttner, R, Wolf, J, Nurnberg, P, Perner, S, Heukamp, L C, Brindle, P K, de Haas, S & Thomas, R K 2012, ' Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer ', Nature Genetics, vol. 44, no. 10, pp. 1104-1110 . https://doi.org/10.1038/ng.2396
Nature Genetics, 44(10), 1104-+. Nature Publishing Group
Nature Genetics; Vol 44
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis(1-3). We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an extremely high mutation rate of 7.4 +/- 1 protein-changing mutations per million bas
Autor:
Sabine Merkelbach-Bruse, Odd Terje Brustugun, Marius Lund-Iversen, Philipp A. Schnabel, Hans Hoffmann, Katharina Koenig, Kato Kambartel, Matthias Scheffler, Reinhard Buettner, Harry J.M. Groen, Jana Fassunke, C. Ligorio, Helen Kuenstlinger, Peter Nuemberg, Sylvie Lantuejoul, William Pao, Philippe Girard, Khosro Hekmat, Johannes Berg, Franziska Gabler, Winfried Randerath, Åslaug Helland, Joerg Saenger, Andreas Schlesinger, Elisabeth Brambilla, Lucia Nogova, Vito Michele Fazio, Monika Serke, Lucia Anna Muscarella, Ines Wilkening, Walburga Engel-Riedel, Sven Perner, Ilona Dahmen, Erich Stoelben, Steinar Solberg, Benjamin Solomon, Hans-Ulrich Schildhaus, Stefan Krueger, Lisa Meffert, Peter M. Schneider, Stefania Damiani, Elke Binot, Katja Schmitz, Toni-Maree Rogers, Ali-Nuri Huenerlituerkoglu, Ulrich Lang, Janine Altmueller, Hannie Sietsma, Chau Nguyen, Lynnette Fernandez-Cuesta, Pierre Validire, Federico Cappuzzo, Christian Mueller, Ulrich Gerigk, Gad Getz, Dirk Behringer, Christian Mattonet, Xin Lu, Wim Timens, Roman K. Thomas, Philippe Lorimier, Masyar Gardizi, Yuan Chen, William D. Travis, Thomas Zander, Prudence A. Russell, Danila Seidel, Marc Bos, Michaela Angelika Kleine, Egbert F. Smit, Matthias Heldwein, Corinna Ludwig, Russell Hyde, Scott L. Carter, Peter J.F. Snijders, Kerstin Albus, Roland Schnell, Alex Soltermann, Michael Hallek, Wolfgang Galetke, Eray Goekkurt, Benjamin Besse, Frauke Leenders, John K. Field, Matthew D. Wilkerson, Roopika Menon, Markus Litt-Lampe, Silvia Querings, Konrad Frank, Yon-Dschun Ko, Holger Moch, Denis Moro-Sibilot, Zoe Wainer, Erik Thunnissen, Lukas C. Heukamp, Walter Weder, Danille A. M. Heideman, Stephan Schmitz, Karin Toepelt, Rainer Kappes, Juergen Wolf, Ingelore Boessmann, Gavin M. Wright, Rainer Fricke, Thomas Muley, Martin L. Sos, Joachim H. Clement, Wolfgang Schulte, Christian Brambilla, Sascha Ansén, Viktor Achter, Jean-Charles Soria, D. Neil Hayes, Martin Peifer, Marcel Reiser, Magdalena Bogus
Publikováno v:
Seidel, D, Zander, T, Heukamp, L C, Peifer, M, Bos, M, Fernandez-Cuesta, L, Leenders, F, Lu, X, Ansen, S, Gardizi, M, Nguyen, C, Berg, J, Russell, P, Wainer, Z, Schildhaus, H U, Rogers, T M, Solomon, B, Pao, W, Carter, S L, Getz, G, Hayes, D N, Wilkerson, M D, Thunnissen, E, Travis, W D, Perner, S, Wright, G, Brambilla, E, Buttner, R, Wolf, J, Gabler, F, Wilkening, I, Muller, C, Dahmen, I, Menon, R, Konig, K, Albus, K, Merkelbach-Bruse, S, Fassunke, J, Schmitz, K, Kuenstlinger, H, Kleine, M A, Binot, E, Querings, S, Altmuller, J, Bossmann, I, Numberg, P, Schneider, P M, Bogus, M, Soltermann, A, Moch, H, Brustugun, O T, Solberg, S, Lund-Iversen, M, Helland, A, Muley, T, Hoffmann, H, Schnabel, P A, Chen, Y, Groen, H, Timens, W, Sietsma, H, Clement, J H, Weder, W, Sanger, J, Stoelben, E, Ludwig, C, Engel-Riedel, W, Smit, E F, Heideman, D A M, Snijders, P J F, Nogova, L, Sos, M L, Mattonet, C, Topelt, K, Scheffler, M, Goekkurt, E, Kappes, R, Kruger, S, Kambartel, K, Behringer, D, Schulte, W, Galetke, W, Randerath, W, Heldwein, M, Schlesinger, A, Serke, M, Hekmat, K, Frank, K F, Schnell, R, Reiser, M, Hunerliturkoglu, A N, Schmitz, S, Meffert, L, Ko, Y D, Litt-Lampe, M, Gerigk, U, Fricke, R, Besse, B, Brambilla, C, Lantuejoul, S, Lorimier, P, Moro-Sibilot, D, Cappuzzo, F, Ligorio, C, Damiani, S, Field, J K, Hyde, R, Validire, P, Girard, P, Muscarella, L A, Fazio, V M, Hallek, M, Soria, J C, Achter, V, Lang, U & Thomas, R K 2013, ' A Genomics-Based Classification of Human Lung Tumors ', Science Translational Medicine, vol. 5, no. 209, pp. 209ra153 . https://doi.org/10.1126/scitranslmed.3006802
Science Translational Medicine; Vol 5
Science Translational Medicine, 5(209). AMER ASSOC ADVANCEMENT SCIENCE
Science Translational Medicine, 5(209). American Association for the Advancement of Science
Science Translational Medicine; Vol 5
Science Translational Medicine, 5(209). AMER ASSOC ADVANCEMENT SCIENCE
Science Translational Medicine, 5(209). American Association for the Advancement of Science
We characterized genome alterations in 1255 clinically annotated lung tumors of all histological subgroups to identify genetically defined and clinically relevant subtypes. More than 55% of all cases had at least one oncogenic genome alteration poten