Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ines Velazquez‐Quesada"'
Tenascin‐C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression
Autor:
Devadarssen Murdamoothoo, Zhen Sun, Alev Yilmaz, Gilles Riegel, Chérine Abou‐Faycal, Claire Deligne, Ines Velazquez‐Quesada, William Erne, Marine Nascimento, Matthias Mörgelin, Gérard Cremel, Nicodème Paul, Raphael Carapito, Romain Veber, Hélène Dumortier, Jingping Yuan, Kim S Midwood, Thomas Loustau, Gertraud Orend
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp 1-21 (2021)
Abstract Immune checkpoint therapy, where CD8 tumor infiltrating T lymphocytes (TIL) are reactivated, is a promising anti‐cancer treatment approach, yet with low response rates. The extracellular matrix, in particular tenascin‐C, may generate bar
Externí odkaz:
https://doaj.org/article/b3b3bbcf9e5c4240a68764406229c8d2
Autor:
Charlotte M. Fonta, Thomas Loustau, Chengbei Li, Suchithra Poilil Surendran, Uwe Hansen, Devadarssen Murdamoothoo, Mario C. Benn, Ines Velazquez-Quesada, Raphael Carapito, Gertraud Orend, Viola Vogel
Publikováno v:
Matrix Biology, 116
Tracks rich in matrix and cells, as described in several cancer types, have immunosuppressive functions and separate tumor nests and stroma, yet their origin is unknown. Immunostainings of cryosections from mouse breast tumors show that these tracks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41be4590845a4c932d78467c1af7d6da
Autor:
Tristan, Rupp, Benoit, Langlois, Maria M, Koczorowska, Agata, Radwanska, Zhen, Sun, Thomas, Hussenet, Olivier, Lefebvre, Devadarssen, Murdamoothoo, Christiane, Arnold, Annick, Klein, Martin L, Biniossek, Vincent, Hyenne, Elise, Naudin, Ines, Velazquez-Quesada, Oliver, Schilling, Ellen, Van Obberghen-Schilling, Gertraud, Orend
Publikováno v:
Cell reports. 17(10)
High expression of the extracellular matrix component tenascin-C in the tumor microenvironment correlates with decreased patient survival. Tenascin-C promotes cancer progression and a disrupted tumor vasculature through an unclear mechanism. Here, we
Autor:
Carlos Fabian, Flores-Jasso, Ines, Velazquez-Quesada, Carlos, Landa-Solis, Andres A, Gutierrez, Luis, Vaca
Publikováno v:
Acta pharmacologica Sinica. 26(12)
To develop an easy, fast, automated, and inexpensive method for constructing short-hairpin-RNA cassettes for RNAi studies.Using single oligonucleotides, a variety of DNA cassettes for RNAi vectors were constructed in only few minutes in an automated
Autor:
Alexia Arpel, Paul Sawma, Caroline Spenlé, Justine Fritz, Lionel Meyer, Norbert Garnier, Inés Velázquez-Quesada, Thomas Hussenet, Samia Aci-Sèche, Nadège Baumlin, Monique Genest, David Brasse, Pierre Hubert, Gérard Crémel, Gertraud Orend, Patrice Laquerrière, Dominique Bagnard
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1714-1721 (2014)
Breast cancer is still a deadly disease despite major achievements in targeted therapies designed to block ligands or ligand-binding subunits of major tyrosine kinase receptors. Relapse is significant and metastases deleterious, which demands novel s
Externí odkaz:
https://doaj.org/article/5035aef430b144c08f074fa6ec612cbd