Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ines Stevic"'
Autor:
Chi Pan, Ines Stevic, Volkmar Müller, Qingtao Ni, Leticia Oliveira‐Ferrer, Klaus Pantel, Heidi Schwarzenbach
Publikováno v:
Molecular Oncology, Vol 12, Iss 11, Pp 1935-1948 (2018)
Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles we
Externí odkaz:
https://doaj.org/article/9ae0c732e1a74f2799e67697d15160b1
Autor:
Ines Stevic, Volkmar Müller, Karsten Weber, Peter A. Fasching, Thomas Karn, Frederic Marmé, Christian Schem, Elmar Stickeler, Carsten Denkert, Marion van Mackelenbergh, Christoph Salat, Andreas Schneeweiss, Klaus Pantel, Sibylle Loibl, Michael Untch, Heidi Schwarzenbach
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background The focus of this study is to identify particular microRNA (miRNA) signatures in exosomes derived from plasma of 435 human epidermal growth factor receptor 2 (HER2)-positive and triple-negative (TN) subtypes of breast cancer (BC).
Externí odkaz:
https://doaj.org/article/c1482c9d621c46d29991f47cf0bdb872
Publikováno v:
Cells, Vol 9, Iss 1, p 130 (2020)
Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a variety of body fluids containing proteins, DNA, RNA species, and lipids, and
Externí odkaz:
https://doaj.org/article/25601f15438c492fb599c4f3ab25afe2
Publikováno v:
RNA Biol
The use of disease-specific signatures of microRNAs (miRNAs) in exosomes has become promising for clinical applications, either as biomarkers or direct therapeutic targets. However, a new approach for exosome enrichment and quantification of miRNAs i
Autor:
Ines Stevic, Franz Ricklefs, Marco Caselli, Valerio Pereno, Krystian D. Fita, Rudolph Reimer, Marceline Manka Fuh, Klaus Pantel, James H. Felce, Hartmut Schlüter, Ulrich Schüller, Guido Reifenberger, Lasse Dührsen, Thomas Sauvigny, Manfred Westphal, Kerstin Kaulich, Tammo Ricklefs, Dieter Henrik Heiland, Markus Glatzel, André Görgens, Katrin Lamszus, Joshua A. Welsh, Simon A. Joosse, Jennifer Jones, Andras G. Miklosi, Cecile L. Maire
Publikováno v:
Neuro Oncol
Background Genome-wide DNA methylation profiling has recently been developed into a tool that allows tumor classification in central nervous system tumors. Extracellular vesicles (EVs) are released by tumor cells and contain high molecular weight DNA
Autor:
Klaus Pantel, Volkmar Müller, Leticia Oliveira-Ferrer, Ines Stevic, Chi Pan, Qingtao Ni, Heidi Schwarzenbach
Publikováno v:
Molecular Oncology, Vol 12, Iss 11, Pp 1935-1948 (2018)
Molecular Oncology
Molecular Oncology
Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles we
Autor:
Klaus Pantel, Jeff Saranchuk, Christine Akrong, Sabine Mai, Heidi Schwarzenbach, Julius Adebayo Awe, Ines Stevic, Darrel Drachenberg, Abeer Al-Qatati
Publikováno v:
International Journal of Cancer. 141:1231-1239
The aim of the current study was to establish a unique expression profile of circulating cell-free microRNAs (miRNAs) capable of differentiating between prostate cancer (PCa) patients with high risk and intermediate risk Gleason scores. MiRNA express
Publikováno v:
Cells, Vol 9, Iss 1, p 130 (2020)
Cells
Cells
Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a variety of body fluids containing proteins, DNA, RNA species, and lipids, and
Autor:
Heidi Schwarzenbach, Qingtao Ni, Klaus Pantel, Leticia Oliveira-Ferrer, Ines Stevic, Chi Pan, Volkmar Müller
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Loading of microRNAs (miRNAs) into exosomes that are involved in cellular communication is a selective process. The current study investigates whether the enrichment of miRNAs in exosomes reflects the pathogenesis of breast cancer (BC) and ductal car
Autor:
Franz Ricklefs, Manfred Westphal, Ines Stevic, Christian Mende, Sven O. Eicker, Jennifer Jones, Katrin Lamszus, Joshua A. Welsh
Publikováno v:
Neuro Oncol
BACKGROUND: Extracellular vesicles (EVs) play an important role in cell-cell communication in different types of tumors, carrying multiple layers of biological functional molecules, including proteins, RNA, DNA and lipids. We previously demonstrated