Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ines Orsolic"'
Publikováno v:
Trends in Genetics. 39:74-88
Cancer was initially considered to be an exclusively genetic disease, but an interplay of dysregulated genetic and epigenetic mechanisms is now known to contribute to the cancer phenotype. More recently, chemical modifications of RNA molecules - the
Autor:
Zlatko Dembic, Siniša Volarević, Slađana Bursać, Ines Orsolic, Irena Drmic Hofman, Jiri Bartek, Deana Jurada, Ivana Mihalek
Publikováno v:
Oncogene
Volume 39
Issue 17
Volume 39
Issue 17
Perturbations in ribosome biogenesis have been associated with cancer. Such aberrations activate p53 through the RPL5/RPL11/5S rRNA complex-mediated inhibition of HDM2. Studies using animal models have suggested that this signaling pathway might cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d47f36aa0267560b68dda91b7cf2b5
https://repository.medri.uniri.hr/islandora/object/medri:3505/datastream/FILE0
https://repository.medri.uniri.hr/islandora/object/medri:3505/datastream/FILE0
Autor:
Moshe Oren, Aristides G. Eliopoulos, Nicholas Pullen, Ines Orsolic, Siniša Volarević, Deana Jurada
Publikováno v:
Seminars in cancer biology
Volume 37-38
Volume 37-38
The nucleolus is the most prominent nuclear substructure assigned to produce ribosomes ; molecular machines that are responsible for carrying out protein synthesis. To meet the increased demand for proteins during cell growth and proliferation the ce
Autor:
Mikael S. Lindström, Jiri Bartek, Sladana Bursac, Siniša Volarević, Deana Jurada, Ines Orsolic
Publikováno v:
Oncogene
Volume 37
Issue 18
Volume 37
Issue 18
The nucleolus is the major site for synthesis of ribosomes, complex molecular machines that are responsible for protein synthesis. A wealth of research over the past 20 years has clearly indicated that both quantitative and qualitative alterations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b522e97d393ad5bf4e8c98019c3b05bd
https://www.bib.irb.hr/930487
https://www.bib.irb.hr/930487
Autor:
Michal Sheffer, Eran Kotler, Ines Orsolic, Tali Shalit, Ohad Tarcic, Moshe Oren, Slađana Bursać, Debora Rosa Bublik, Odelia Mouhadeb, Siniša Volarević, Yishai Levin, Gilad Fuchs, Yonit Hoffman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Volume 114
Issue 4
Volume 114
Issue 4
The microRNA miR-504 targets TP53 mRNA encoding the p53 tumor suppressor. miR-504 resides within the fibroblast growth factor 13 (FGF13) gene, which is overexpressed in various cancers. We report that the FGF13 locus, comprising FGF13 and miR-504, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38283f53d8422be86c85bfb75f6fa5c3
https://doi.org/10.1073/pnas.1614876114
https://doi.org/10.1073/pnas.1614876114
Autor:
Vassilis Zoumpourlis, Jiri Bartek, Thanos D. Halazonetis, Ayguel Dereli-Oz, Wei Gu, Jirina Bartkova, Sladana Bursac, Siniša Volarević, Theodoros I. Roumeliotis, Apostolos Klinakis, Dimitris Kletsas, Kostas Evangelou, Georgia Velimezi, Maria Sideridou, Maja Cokaric-Brdovcak, Athanassios Kotsinas, Michalis Liontos, Vassilis G. Gorgoulis, Konstantinos Vougas, Ioannis S. Pateras, Maciej K. Kocylowski, Ines Orsolic, George Papafotiou
Publikováno v:
Nature cell biology
The DNA damage response (DDR) pathway and ARF function as barriers to cancer development. Although commonly regarded as operating independently of each other, some studies proposed that ARF is positively regulated by the DDR. Contrary to either scena
Autor:
Vedrana Filić, Siniša Volarević, Kristina Grabušić, Moshe Oren, Carol Prives, Martin Pfannkuchen, Maja Cokarić Brdovčak, Lilyn Daftuar, Lior Golomb, Ines Orsolic, Iva Vukelić, Yan Zhu, Chen Katz, Sladana Bursac
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 109
Proceedings of the National Academy of Sciences
Volume 109
Issue 50
Proceedings of the National Academy of Sciences
Volume 109
Issue 50
Impairment of ribosomal biogenesis can activate the p53 protein independently of DNA damage. The ability of ribosomal proteins L5, L11, L23, L26, or S7 to bind Mdm2 and inhibit its ubiquitin ligase activity has been suggested as a critical step in p5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4118943a53a10bac70cef442097c6ee2
https://urn.nsk.hr/urn:nbn:hr:184:046759
https://urn.nsk.hr/urn:nbn:hr:184:046759
Autor:
Georgia Velimezi, Michalis Liontos, Konstantinos Vougas, Theodoros Roumeliotis, Jirina Bartkova, Maria Sideridou, Ayguel Dereli-Oz, Maciej Kocylowski, Ioannis S. Pateras, Kostas Evangelou, Athanassios Kotsinas, Ines Orsolic, Sladana Bursac, Maja Cokaric-Brdovcak, Vassilis Zoumpourlis, Dimitris Kletsas, George Papafotiou, Apostolos Klinakis, Sinisa Volarevic, Wei Gu, Jiri Bartek, Thanos D. Halazonetis, Vassilis G. Gorgoulis
Publikováno v:
Nature Cell Biology. 15:1260-1260