Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ines Krüger"'
Autor:
Bernardo Ramírez-Zavala, Ines Krüger, Sonja Schwanfelder, Katherine S. Barker, P. David Rogers, Joachim Morschhäuser
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT Zinc cluster transcription factors (ZCFs) are a family of transcription regulators that are almost exclusively found in the fungal kingdom. Activating mutations in the ZCFs Mrr1, Tac1, and Upc2 frequently cause acquired resistance to the wid
Externí odkaz:
https://doaj.org/article/959ece019a014963bd83a4e42dfb6f10
Autor:
Bernardo Ramírez-Zavala, Anna Hoffmann, Ines Krüger, Sonja Schwanfelder, Katherine S. Barker, P. David Rogers, Joachim Morschhäuser
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT The adaptation of gene deletion methods based on the CRISPR-Cas9 system has facilitated the genetic manipulation of the pathogenic yeast Candida albicans, because homozygous mutants of this diploid fungus can now be generated in a single ste
Externí odkaz:
https://doaj.org/article/e514b24a1a9d4199ac7bc328f8d87fb0
Autor:
Bernardo Ramírez-Zavala, Darina Betsova, Sonja Schwanfelder, Ines Krüger, Austin Mottola, Thomas Krüger, Olaf Kniemeyer, Axel A. Brakhage, Joachim Morschhäuser
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTThe highly conserved heterotrimeric protein kinase SNF1 is important for metabolic adaptations in the pathogenic yeast Candida albicans. A key function of SNF1 is to inactivate the repressor protein Mig1 and thereby allow the expression of ge
Externí odkaz:
https://doaj.org/article/d8d62bc842d749c28592f7bd32e84e94
Autor:
Bernardo Ramírez-Zavala, Ines Krüger, Andreas Wollner, Sonja Schwanfelder, Joachim Morschhäuser
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010890 (2023)
Protein kinases are central components of almost all signaling pathways that control cellular activities. In the model organism Saccharomyces cerevisiae, the paralogous protein kinases Ypk1 and Ypk2, which control membrane lipid homeostasis, are esse
Externí odkaz:
https://doaj.org/article/dff3f87ff9ec40e08b36d6aca1d46b9b
Autor:
Bernardo Ramírez-Zavala, Ines Krüger, Christine Dunker, Ilse D Jacobsen, Joachim Morschhäuser
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010283 (2022)
Protein kinases play central roles in virtually all signaling pathways that enable organisms to adapt to their environment. Microbial pathogens must cope with severely restricted iron availability in mammalian hosts to invade and establish themselves
Externí odkaz:
https://doaj.org/article/2de2097e8b6d45b78049f183bad71f30
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT The heterotrimeric protein kinase SNF1 is a key regulator of metabolic adaptation in the pathogenic yeast Candida albicans, and mutants with a defective SNF1 complex cannot grow on carbon sources other than glucose. We identified a novel typ
Externí odkaz:
https://doaj.org/article/6a31461f54aa494183bfe30ca5d4550c
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT The recently emerged pathogenic yeast Candida auris is a major concern for human health, because it is easily transmissible, difficult to eradicate from hospitals, and highly drug resistant. Most C. auris isolates are resistant to the widely
Externí odkaz:
https://doaj.org/article/52fa267fa7b3472580f15eb19d6f5c1d
Autor:
Christina Popp, Bernardo Ramírez-Zavala, Sonja Schwanfelder, Ines Krüger, Joachim Morschhäuser
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The clonal population structure of Candida albicans suggests that (para)sexual recombination does not play an important role in the lifestyle of this opportunistic fungal pathogen, an assumption that is strengthened by the fact that most C.
Externí odkaz:
https://doaj.org/article/9ac3fa45865f4cf384a318860cc528e9
Autor:
Bernardo Ramírez-Zavala, Ines Krüger, Christine Dunker, Ilse D. Jacobsen, Joachim Morschhäuser
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010283 (2022)
Protein kinases play central roles in virtually all signaling pathways that enable organisms to adapt to their environment. Microbial pathogens must cope with severely restricted iron availability in mammalian hosts to invade and establish themselves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da5b33660791c00e836895d6389b18b
https://pubmed.ncbi.nlm.nih.gov/35108336
https://pubmed.ncbi.nlm.nih.gov/35108336
Publikováno v:
Nucleic Acids Research. 32:2677-2684
The influence of cell cycle phase on the fidelity of DNA double-strand break (DSB) repair is largely unknown. We investigated the rejoining of correct and incorrect DSB ends in synchronized populations of Chinese hamster ovary cells irradiated with 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993bdeb905b390b1108941ecdbb2b313
https://doi.org/10.1093/nar/gkh586
https://doi.org/10.1093/nar/gkh586