Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ines Koch"'
Autor:
Teodor G. Calina, Eilís Perez, Elena Grafenhorst, Jamal Benhamida, Simon Schallenberg, Adrian Popescu, Ines Koch, Tobias Janik, BaoQing Chen, Jana Ihlow, Stephanie Roessler, Benjamin Goeppert, Bruno Sinn, Marcus Bahra, George A. Calin, Eliane T. Taube, Uwe Pelzer, Christopher C. M. Neumann, David Horst, Erik Knutsen, David Capper, Mihnea P. Dragomir
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver metastasis and intrahepatic cholangiocarcinoma (iCCA) with high accuracy (PAAD-iCCA-Classifier).
Externí odkaz:
https://doaj.org/article/6d749e8836f14bb88e912de9ad31cd5f
Autor:
Reinhard Büttner, Sabine Merkelbach-Bruse, Sandip Ghosh, Alexander Quaas, Khosro Hekmat, Matthias Heldwein, Frederick Klauschen, Ulrich Keilholz, Angela Vasaturo, Nikolaj Frost, David Horst, Simon Schallenberg, Gabriel Dernbach, Sharon Ruane, Cornelius Böhm, Lukas Ruff, Kai Standvoss, Mihnea P Dragomir, Rebecca Fritz, Ines Koch, Corinna Friedrich, Kyrill Boschung, Winfried Randerath, Georg Schlachtenberger, Jens-Carsten Rückert, Maximilian Alber
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/edaf4c73a1c44fdcabb8b857eb576a54
Autor:
Mihnea P. Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Erik Knutsen, Aiham Qdaisat, Meng Chen, Yongfeng Li, Masayoshi Shimizu, Lan Pang, Kevin Liu, Xiuping Liu, Simone Anfossi, Huanyu Zhang, Ines Koch, Anh M. Tran, Swati Mohapatra, Anh Ton, Mecit Kaplan, Matthew W. Anderson, Spencer J. Rothfuss, Robert Silasi, Ravi S. Keshari, Manuela Ferracin, Cristina Ivan, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Constantin Georgescu, Pinaki P. Banerjee, Rafet Basar, Ziyi Li, David Horst, Catalin Vasilescu, Maria Teresa S. Bertilaccio, Katayoun Rezvani, Florea Lupu, Sai-Ching Yeung, George A. Calin
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In the past decade, deciphering the functions of small noncod
Externí odkaz:
https://doaj.org/article/d4033ceefb364ffba4d3f09a718cc569
Autor:
Mihnea P. Dragomir, Teodor G. Calina, Eilís Perez, Simon Schallenberg, Meng Chen, Thomas Albrecht, Ines Koch, Peggy Wolkenstein, Benjamin Goeppert, Stephanie Roessler, George A. Calin, Christine Sers, David Horst, Florian Roßner, David Capper
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104657- (2023)
Summary: Background: Differentiating intrahepatic cholangiocarcinomas (iCCA) from hepatic metastases of pancreatic ductal adenocarcinoma (PAAD) is challenging. Both tumours have similar morphological and immunohistochemical pattern and share multiple
Externí odkaz:
https://doaj.org/article/db8391b0915642daa4b44af43c287256
Publikováno v:
BMC Medical Education, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Medical schools globally now use objective structured clinical examinations (OSCEs) for assessing a student’s clinical performance. In Germany, almost all of the 36 medical schools have incorporated at least one summative OSCE i
Externí odkaz:
https://doaj.org/article/153eac0ac6794439b5eecbe549dcdcb2
Autor:
David Capper, Peggy Wolkenstein, Inga Hoffmann, Claudia Vollbrecht, Frederick Klauschen, Ines Koch, Philipp Jurmeister, Niklas Wrede, Maximilian von Laffert
Publikováno v:
Pathology, research and practice. 229
Mucosal melanomas arise from the mucosal lining of various organs. Their etiology is currently unknown and there are no tissue-based methods to differentiate it from cutaneous melanomas. Furthermore, prognostic and predictive markers (e.g. for immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7b5d76e8957c4dd0035051c31c890c
https://pubmed.ncbi.nlm.nih.gov/34844086
https://pubmed.ncbi.nlm.nih.gov/34844086
Autor:
Christine Sers, Michael Hummel, Daniel Heim, Ines Koch, Philipp Jurmeister, Niklas Wrede, Verena Heynol, David Capper, Maximilian von Laffert, Wolfgang D. Schmitt, Claudia Vollbrecht, Daniel Teichmann, Andreas von Deimling, Anne Thieme, Julia Thierauf, Inga Hoffmann, Peggy Wolkenstein, Frederick Klauschen
Cutaneous, ocular, and mucosal melanomas are histologically indistinguishable tumors that are driven by a different spectrum of genetic alterations. With current methods, identification of the site of origin of a melanoma metastasis is challenging. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc9b05c2f2b5e276ecbba1c4f2dc812
Autor:
Michael Untch, Andreas Schneeweiss, Frank L. Heppner, Valentina Nekljudova, Peter A. Fasching, G. von Minckwitz, J-U Blohmer, C Denkert, Ines Koch, Giuseppe Aprile, B-I Heppner, V Müller, S. Loibl, B. Lederer, Fabio Puglisi, Claire Gehlhaar, C. Jackisch, C Fontanella
Publikováno v:
Cancer Research. 76:P3-07
Background: The epigenetic profile of triple-negative breast cancer (TNBC) showed a wide prevalence of MGMT promoter methylation.Aberrant methylation of MGMT seems to be an independent predictor of poor survival in patients with basal-like breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b72b25becfecc3d012c4e23d6daa5ad
https://doi.org/10.1158/1538-7445.sabcs15-p3-07-55
https://doi.org/10.1158/1538-7445.sabcs15-p3-07-55
Autor:
Sibylle Loibl, Ines Koch, Judith Prinzler, Jan Budczies, Annika Lehmann, Christiane Schewe, Ruza Arsenic, Manfred Dietel, Anke Kleine-Tebbe, Carsten Denkert
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 22:50-56
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit α (PIK3CA) is a central element of a signaling pathway involved in cell proliferation, survival, and growth. Certain mutations in this pathway result in enhanced PI3K signaling, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdae6d25995239ab5e5bed92f24ed96a
https://doi.org/10.1097/pdm.0b013e318297afea
https://doi.org/10.1097/pdm.0b013e318297afea
Autor:
Aurelia Noske, Birgit Schaefer, Jalid Sehouli, Manfred Dietel, Silvia Niesporek, Alexander Kaszubiak, Ines Koch, Wilko Weichert, Christine Sers, Herman Lage, Carsten Denkert
Publikováno v:
Cancer Letters. 246:190-200
The protein kinase AKT is involved in several signaling pathways that are important for tumor development and progression, suggesting that AKT might be an interesting target for a molecular tumor therapy. In this study, we investigated the AKT expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce8bacfa40a935d486847ce0bcfa545
https://doi.org/10.1016/j.canlet.2006.02.018
https://doi.org/10.1016/j.canlet.2006.02.018