Výsledky vyhledávání - "Ines Brueckmann"

Treatment with SDZ-ADL, an Adalimumab Biosimilar, in Patients with Rheumatoid Arthritis, Psoriasis, or Psoriatic Arthritis: Results of Patient-Reported Outcome Measures from Two Phase III Studies (ADMYRA and ADACCESS)

Autor: Craig L. Leonardi, Lena Lemke, Sohaib Hachaichi, Alison Balfour, Julia Jauch-Lembach, Norman Gaylis, Ines Brueckmann, Teodora Festini, Andrew Blauvelt, Piotr Wiland

Publikováno v: Biodrugs

Background SDZ-ADL (GP2017; Sandoz GmbH, Austria) is an EMA-/FDA-approved adalimumab biosimilar. The effect of SDZ-ADL on quality of life (QoL) and patient-reported outcomes (PROs) was assessed as part of two phase III studies, one in patients with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b429e4018b2ffd869924b21ef7b444e4
https://doi.org/10.1007/s40259-021-00470-1

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Switching to Biosimilar SDZ-ADL in Patients with Moderate-to-Severe Active Rheumatoid Arthritis: 48-Week Efficacy, Safety and Immunogenicity Results From the Phase III, Randomized, Double-Blind ADMYRA Study

Autor: Eva Dokoupilova, Raul Maria Veiga Cabello, Juan Manuel Miranda Limon, Norman Gaylis, Halimuniyazi Haliduola, Piotr Wiland, Anjali Thakur, Jan Brandt-Jürgens, Miguel Cantalejo Moreira, Sławomir Jeka, Julia Jauch-Lembach, Ines Brueckmann

Publikováno v: Biodrugs

Background Sandoz adalimumab SDZ-ADL (GP-2017) is an approved adalimumab biosimilar with similar efficacy and comparable safety and immunogenicity to reference adalimumab (ref-ADL) as confirmed by analytical, pharmacokinetic and confirmatory studies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f31386a60739f623d4013ff3a44f86b
https://doi.org/10.1007/s40259-020-00447-6

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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

Autor: Robert A. Weinberg, Ying Su, Brian Bierie, Christine L. Chaffer, Christina Scheel, Lisa M. Arendt, Paul A. Wiggins, Kornelia Polyak, Leonardo O. Rodrigues, Alicia J. Kaestli, Ferenc Reinhardt, Mary W. Brooks, Ines Brueckmann, Charlotte Kuperwasser

Publikováno v: Proceedings of the National Academy of Sciences. 108:7950-7955

Current models of stem cell biology assume that normal and neoplastic stem cells reside at the apices of hierarchies and differentiate into nonstem progeny in a unidirectional manner. Here we identify a subpopulation of basal-like human mammary epith

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb6865147dd5b4494dc96062c7ff909
https://doi.org/10.1073/pnas.1102454108

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Multiple myeloma-related deregulation of bone marrow-derived CD34+ hematopoietic stem and progenitor cells

Multiple myeloma (MM) is a clonal plasma cell disorder frequently accompanied by hematopoietic impairment. We show that hematopoietic stem and progenitor cells (HSPCs), in particular megakaryocyte-erythrocyte progenitors, are diminished in the BM of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d390b9f320f3a1a74274713c3a7c1f
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84866856496

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