Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Ines Batinic‐Haberle"'
Autor:
Sun Up Noh, Jinyeong Lim, Sung-Won Shin, Yeeun Kim, Woong-Yang Park, Ines Batinic-Haberle, Changhoon Choi, Won Park
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 477 (2024)
Manganese porphyrins reportedly exhibit synergic effects when combined with irradiation. However, an in-depth understanding of intratumoral heterogeneity and immune pathways, as affected by Mn porphyrins, remains limited. Here, we explored the mechan
Externí odkaz:
https://doaj.org/article/313101eaefc24be3a8dd5c5e871dac6f
Autor:
Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang, Zhong Yang, Xingguang Qu, Zhenxing Yang, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, James D. Crapo, Miriam M. Treggiari, Huaxin Sheng
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1861 (2023)
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Manganese porphyri
Externí odkaz:
https://doaj.org/article/cd7bd498d53b459a86835b675ccfbd52
Publikováno v:
Redox Report, Vol 26, Iss 1, Pp 85-93 (2021)
Objective The aim of this study was to investigate how modifications at the periphery of the porphyrin ring affect the anticancer activity of Mn porphyrins (MnPs)-based SOD mimics. Methods Six compounds: MnTE-2-PyP with a short ethyl chain on the pyr
Externí odkaz:
https://doaj.org/article/1a3613e211b945e48e769b319a448a3d
Autor:
Rita B. Soares, Rita Manguinhas, João G. Costa, Nuno Saraiva, Nuno Gil, Rafael Rosell, Sérgio P. Camões, Ines Batinic-Haberle, Ivan Spasojevic, Matilde Castro, Joana P. Miranda, Filipa Amaro, Joana Pinto, Ana S. Fernandes, Paula Guedes de Pinho, Nuno G. Oliveira
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2198 (2022)
The manganese(III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including cancer. Nevertheless
Externí odkaz:
https://doaj.org/article/67a72876692d4ab0aff01917ce527f4b
Autor:
Peng Wang, Ying Li, Baihui Yan, Zhong Yang, Litao Li, Zhipeng Cao, Xuan Li, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, Huaxin Sheng
Publikováno v:
Biology, Vol 11, Iss 7, p 957 (2022)
Introduction Cardiac arrest (CA) and resuscitation induces global cerebral ischemia and reperfusion, causing neurologic deficits or death. Manganese porphyrins, superoxide dismutase mimics, are reportedly able to effectively reduce ischemic injury in
Externí odkaz:
https://doaj.org/article/d4801eb592674fea9a873bfe3ebe760a
Autor:
Ana Flórido, Nuno Saraiva, Sara Cerqueira, Nuno Almeida, Maddy Parsons, Ines Batinic-Haberle, Joana P. Miranda, João G. Costa, Guia Carrara, Matilde Castro, Nuno G. Oliveira, Ana S. Fernandes
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 367-378 (2019)
Manganese(III) porphyrins (MnPs) are superoxide dismutase (SOD) mimics with demonstrated beneficial effects in cancer treatment in combination with chemo- and radiotherapy regimens. Despite the ongoing clinical trials, little is known about the effec
Externí odkaz:
https://doaj.org/article/2187bc21422b4a2db5e3ceee7004d36e
Autor:
Gregory Lucien Bellot, Xiaoke Dong, Amitabha Lahiri, Sandeep Jacob Sebastin, Ines Batinic-Haberle, Shazib Pervaiz, Mark Edward Puhaindran
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 307-320 (2019)
Negative Pressure Wound Therapy (NPWT), a widely used modality in the management of surgical and trauma wounds, offers clear benefits over conventional wound healing strategies. Despite the wide-ranging effects ascribed to NPWT, the precise molecular
Externí odkaz:
https://doaj.org/article/ffc69691498340468b0e36780ebd005f
Autor:
Eva Sidlauskaite, Jack W. Gibson, Ian L. Megson, Philip D. Whitfield, Artak Tovmasyan, Ines Batinic-Haberle, Michael P. Murphy, Peter R. Moult, James N. Cobley
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 344-351 (2018)
Developmental synapse pruning refines burgeoning connectomes. The basic mechanisms of mitochondrial reactive oxygen species (ROS) production suggest they select inactive synapses for pruning: whether they do so is unknown. To begin to unravel whether
Externí odkaz:
https://doaj.org/article/fca4c7ad6eb0495584bcf05714886d01
Autor:
Sung-Won Shin, Changhoon Choi, Hakyoung Kim, Yeeun Kim, Sohee Park, Shin-Yeong Kim, Ines Batinic-Haberle, Won Park
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1769 (2021)
Tumor migration and invasion induced by the epithelial-to-mesenchymal transition (EMT) are prerequisites for metastasis. Here, we investigated the inhibitory effect of a mimic of superoxide dismutase (SOD), cationic Mn(III) ortho-substituted N-n-hexy
Externí odkaz:
https://doaj.org/article/5b507cbe7fe8409d8046bef1324cff8d
Autor:
David Leu, Ivan Spasojevic, Huy Nguyen, Brian Deng, Artak Tovmasyan, Tin Weitner, Romulo S. Sampaio, Ines Batinic-Haberle, Ting-Ting Huang
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 864-871 (2017)
Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal tissues is presented, in part, as suppressed
Externí odkaz:
https://doaj.org/article/016abf0fa83f4201af38fa42784e66f7