Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Ines B Brecht"'
Autor:
Daniela Di Carlo, Giulia Fichera, Benoit Dumont, Enrico Pozzo, Beate Timmermann, Romain Luscan, Antoine Moya-Plana, Anna Synakiewicz, Ewa Bien, Nino Jorge dos Reis Farinha, Malgorzata Krawczyk, Rita Alaggio, Apostolos Pourtsidis, Brice Fresneau, Yves Reguerre, Tal Ben-Ami, Calogero Virgone, Jelena Roganovic, Jan Godzinski, Ines B Brecht, Dominik Schneider, Andrea Ferrari, Barbara Hero, Daniel Orbach, Gianni Bisogno
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100136- (2024)
Olfactory neuroblastoma (ON) is a rare tumor commonly presenting between 50 and 60 years of age. In pediatric age this tumor is even rarer, with an estimated incidence of 0.1 per 100,000 children up to 15 years. It arises from the olfactory neurorepi
Externí odkaz:
https://doaj.org/article/63347801e0a243b0bc1bc645d4cb7d88
Autor:
Malgorzata A. Krawczyk, Malgorzata Styczewska, Carla Fernandez, Rita Alaggio, Jaroslaw Szydlowski, Ines B. Brecht, Daniel Orbach, Dominik T. Schneider, Jelena Roganovic, Gianni Bisogno, Calogero Virgone, Jan Godzinski, Andrea Ferrari, Nuno Jorge Farinha, Tal Ben Ami, Luca Bergamaschi, Yves Réguerre, Ewa Bien
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100141- (2024)
Melanotic neuroectodermal tumor of infancy (MNTI) is a very rare benign neoplasm of probable neurocristic origin. It primarily affects children in the first year of life, with the median age at diagnosis of 4.5 months (range 0–804 months). It usual
Externí odkaz:
https://doaj.org/article/8f796361f1dc4e45bfa1999b29c96f1d
Autor:
Dominik T. Schneider, Andrea Ferrari, Daniel Orbach, Calogero Virgone, Yves Reguerre, Jan Godzinski, Ewa Bien, Jelena Roganovic, Nuno Reis Farinha, Tal Ben-Ami, Teresa Stachowicz-Stencel, Tabea Blessing, Antje Redlich, Apostolos Pourtsidis, Kris Ann P. Schultz, Ines B. Brecht, Gianni Bisogno
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100137- (2024)
Background: Very rare tumors (VRTs) in children and adolescents are orphan diseases defined by an annual incidence of
Externí odkaz:
https://doaj.org/article/f8238ed80f0344d38345f67c73645da6
Autor:
Calogero Virgone, Tal Ben Ami, Jelena Roganovic, Ewa Bien, Yves Reguerre, Andrea Ferrari, Daniel Orbach, Jan Godzinski, Gianni Bisogno, Nuno Jorge Farinha, Luca Bergamaschi, Rita Alaggio, Michaela Kuhlen, Michael Abele, Abbas Agaimy, Dominik T. Schneider, Ines B. Brecht
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100027- (2023)
Very rare tumors (VRTs) in pediatric age represent many different diseases. They present an annual incidence
Externí odkaz:
https://doaj.org/article/d2ac71f6c0b24d4782e2aa27af78513d
Autor:
Daniel Orbach, Ines B. Brecht, Nadege Corradini, Yassine Bouchoucha, Jelena Roganovic, Franck Bourdeaut, Yves Reguerre, Roland P. Kuiper, Brigitte Bressac de Paillerets, Andrea Ferrari, Calogero Virgone, Jan Godzinski, Gianni Bisogno, Lea Guerrini-Rousseau, Nuno Jorge Farinha, Luca Bergamaschi, Ewa Bien, Michaela Kuhlen, Dominik T. Schneider, Tal Ben Ami
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100023- (2023)
Germline predisposing pathogenic variants (GPVs) are present in approximately 8–10 % of children with all cancer types. Very rare tumours (VRTs) represent many different diseases, defined with an annual incidence
Externí odkaz:
https://doaj.org/article/d62e20c9c6424c0bb4631c4a7f0fd964
Autor:
Jelena Roganovic, Ewa Bien, Andrea Ferrari, Gilles Vassal, Annalisa Trama, Paolo G. Casali, Annita Kienesberger, Gianni Bisogno, Calogero Virgone, Tal Ben Ami, Yves Reguerre, Jan Godzinski, Nuno Jorge Farinha, Luca Bergamaschi, Dominik T. Schneider, Daniel Orbach, Ines B. Brecht
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100130- (2023)
Very rare cancers in children and adolescents pose a unique challenge for optimal care and research. Due to their rarity and diversity, there is a lack of standardized treatments and limited data to guide clinical decision-making. This paper aims to
Externí odkaz:
https://doaj.org/article/4258fb889aab474eb2b3e91f04e639d6
Autor:
Dominik T. Schneider, Daniel Orbach, Calogero Virgone, Yves Reguerre, Jan Godzinski, Ewa Bien, Gianni Bisogno, Jelena Roganovic, Nuno Reis Farinha, Tal Ben-Ami, Teresa Stachowicz-Stencel, Anna Synakiewicz, Bernadette Brennan, Stefano Chiaravalli, Benedikt Bernbeck, Coralie Mallebranche, Vincent Couloigner, Michael Abele, Ines B. Brecht, Andrea Ferrari
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100129- (2023)
Background: Salivary gland carcinomas (SGCs) are exceedingly rare in children, with a reported annual incidence of 0.8–1.4/1000,000 under 20 years of age. Evidence regarding optimal treatment of pediatric SGCs is limited, and for a long time, no gu
Externí odkaz:
https://doaj.org/article/ddc7cbd36d484199988b1d7cff27f17c
Autor:
Ghada M. H. Abdel-Salam, Susanne Hellmuth, Elise Gradhand, Stephan Käseberg, Jennifer Winter, Ann-Sophie Pabst, Maha M. Eid, Holger Thiele, Peter Nürnberg, Birgit S. Budde, Mohammad Reza Toliat, Ines B. Brecht, Christopher Schroeder, Axel Gschwind, Stephan Ossowski, Friederike Häuser, Heidi Rossmann, Mohamed S. Abdel-Hamid, Ibrahim Hegazy, Ahmed G. Mohamed, Dominik T. Schneider, Aida Bertoli-Avella, Peter Bauer, Jillian N. Pearring, Rolph Pfundt, Alexander Hoischen, Christian Gilissen, Dennis Strand, Ulrich Zechner, Soha A. Tashkandi, Eissa A. Faqeih, Olaf Stemmann, Susanne Strand, Hanno J. Bolz
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
MAD2L1BP-encoded p31comet mediates Trip13-dependent disassembly of Mad2- and Rev7-containing complexes and, through this antagonism, promotes timely spindle assembly checkpoint (SAC) silencing, faithful chromosome segregation, insulin signaling, and
Externí odkaz:
https://doaj.org/article/c2f7dbb684e54ea28e6d06a849f00507
Autor:
Alexandra Liebmann, Jakob Admard, Sorin Armeanu-Ebinger, Hannah Wild, Michael Abele, Axel Gschwind, Olga Seibel-Kelemen, Christian Seitz, Irina Bonzheim, Olaf Riess, German Demidov, Marc Sturm, Malou Schadeck, Michaela Pogoda, Ewa Bien, Malgorzata Krawczyk, Eva Jüttner, Thomas Mentzel, Maja Cesen, Elke Pfaff, Michal Kunc, Stephan Forchhammer, Andrea Forschner, Ulrike Leiter-Stöppke, Thomas K. Eigentler, Dominik T. Schneider, Christopher Schroeder, Stephan Ossowski, Ines B. Brecht
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104797- (2023)
Summary: Background: Genomic characterisation has led to an improved understanding of adult melanoma. However, the aetiology of melanoma in children is still unclear and identifying the correct diagnosis and therapeutic strategies remains challenging
Externí odkaz:
https://doaj.org/article/127dec53e6d3434d85e40f46cbf6798e
Autor:
Jens Bauer, Natalie Köhler, Yacine Maringer, Philip Bucher, Tatjana Bilich, Melissa Zwick, Severin Dicks, Annika Nelde, Marissa Dubbelaar, Jonas Scheid, Marcel Wacker, Jonas S. Heitmann, Sarah Schroeder, Jonas Rieth, Monika Denk, Marion Richter, Reinhild Klein, Irina Bonzheim, Julia Luibrand, Ursula Holzer, Martin Ebinger, Ines B. Brecht, Michael Bitzer, Melanie Boerries, Judith Feucht, Helmut R. Salih, Hans-Georg Rammensee, Stephan Hailfinger, Juliane S. Walz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The DNAJB1-PRKACA fusion transcript is the oncogenic driver in fibrolamellar hepatocellular carcinoma, a lethal disease with limited therapeutic options. Here, the authors identify the DNAJB1-PRKACA protein as a source for immunogenic neoepitopes and
Externí odkaz:
https://doaj.org/article/3a134c49c74b482cbf740f80cccba049