Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ines Ambite"'
Autor:
Farhan Haq, Samudra Sabari, Jaromir Háček, Antonín Brisuda, Ines Ambite, Michele Cavalera, Parisa Esmaeili, Murphy Lam Yim Wan, Shahram Ahmadi, Marek Babjuk, Catharina Svanborg
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Background The tumoricidal complex alpha1‐oleate targets bladder cancer cells, triggering rapid, apoptosis‐like tumor cell death. Clinical effects of alpha1‐oleate were recently observed in patients with non‐muscle invasive bladder c
Externí odkaz:
https://doaj.org/article/b5d29c498cd44e9d837e274d4f7f27ed
Autor:
Hien Thi Tran, Murphy Lam Yim Wan, Ines Ambite, Michele Cavalera, Mario Grossi, Jaromir Háček, Parisa Esmaeili, António N. B. M. Carneiro, Arunima Chaudhuri, Shahram Ahmadi, Catharina Svanborg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Though new targeted therapies for colorectal cancer, which progresses from local intestinal tumors to metastatic disease, are being developed, tumor specificity remains an important problem, and side effects a major concern. Here, we show th
Externí odkaz:
https://doaj.org/article/5d4193e27f994f76a38cd041fc8fd884
Autor:
Shahram Ahmadi, Ines Ambite, Antonín Brisuda, Jaromír Háček, Farhan Haq, Samudra Sabari, Kamala Vanarsa, Chandra Mohan, Marek Babjuk, Catharina Svanborg
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Background The molecular content of urine is defined by filtration in the kidneys and by local release from tissues lining the urinary tract. Pathological processes and different therapies change the molecular composition of urine and a vari
Externí odkaz:
https://doaj.org/article/d9d6a4ef0c0c41bcab5c8fb424a1b0ca
Autor:
Ines Ambite, Thi Hien Tran, Daniel S. C. Butler, Michele Cavalera, Murphy Lam Yim Wan, Shahram Ahmadi, Catharina Svanborg
Publikováno v:
Pathogens, Vol 13, Iss 1, p 42 (2023)
Innate immunity is essential for the anti-microbial defense, but excessive immune activation may cause severe disease. In this study, immunotherapy was shown to prevent excessive innate immune activation and restore the anti-bacterial defense. E. col
Externí odkaz:
https://doaj.org/article/b944b834c8904e4c93330d4ab6e90837
Autor:
Björn Wullt, Daniel S.C. Butler, Ines Ambite, Julia Kinsolving, Christian Krintel, Catharina Svanborg
Publikováno v:
European Urology Open Science, Vol 31, Iss , Pp 49-58 (2021)
Background: Patients with bladder pain syndrome experience debilitating pain and extreme frequency of urination. Numerous therapeutic approaches have been tested, but as the molecular basis of disease has remained unclear, specific therapies are not
Externí odkaz:
https://doaj.org/article/ebc6dd798384437c941a97fdf45843f2
Autor:
Antonín Brisuda, James C. S. Ho, Pancham S. Kandiyal, Justin T-Y. Ng, Ines Ambite, Daniel S. C. Butler, Jaromir Háček, Murphy Lam Yim Wan, Thi Hien Tran, Aftab Nadeem, Tuan Hiep Tran, Anna Hastings, Petter Storm, Daniel L. Fortunati, Parisa Esmaeili, Hana Novotna, Jakub Horňák, Y. G. Mu, K. H. Mok, Marek Babjuk, Catharina Svanborg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Partially unfolded alpha-lactalbumin forms an oleic acid complex with antitumorigenic properties. Here, the authors define a structurally flexible, peptide-based oleate complex and report a phase I/II clinical trial where this complex is used to trea
Externí odkaz:
https://doaj.org/article/8bab807c461e46258408ec0d77b8d766
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 5 (2021)
The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and results of a
Externí odkaz:
https://doaj.org/article/4a39033b6e7a4d48b1371a6cee000a62
Autor:
Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005848 (2016)
Tissue damage is usually regarded as a necessary price to pay for successful elimination of pathogens by the innate immune defense. Yet, it is possible to distinguish protective from destructive effects of innate immune activation and selectively att
Externí odkaz:
https://doaj.org/article/179d246158654051a6907866773658fa
Autor:
Ines Ambite, Nataliya Lutay, Christoph Stork, Ulrich Dobrindt, Björn Wullt, Catharina Svanborg
Publikováno v:
Pathogens, Vol 5, Iss 3, p 49 (2016)
Asymptomatic bacteriuria (ABU) is a bacterial carrier state in the urinary tract that resembles commensalism at other mucosal sites. ABU strains often lack the virulence factors that characterize uropathogenic Escherichia coli (E. coli) strains and t
Externí odkaz:
https://doaj.org/article/ae31fe43550a4a79b21d81f9afc3436c
Autor:
Yang Liu, Manoj Puthia, Eamon J. Sheehy, Ines Ambite, Jitka Petrlova, Sujeethkumar Prithviraj, Maria Wimer Oxborg, Sujeesh Sebastian, Corina Vater, Stefan Zwingenberger, André Struglics, Paul E. Bourgine, Fergal J. O'Brien, Deepak Bushan Raina
Publikováno v:
Acta Biomaterialia. 162:164-181