Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ines, Vermeire"'
Autor:
Ellen Vercalsteren, Christine Vranckx, Ines Vermeire, Max Gooijen, Roger Lijnen, Ilse Scroyen
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 242-250 (2021)
Obesity, caused by an excess adipose tissue, is one of the biggest health-threats of the 21st century. Adipose tissue expansion occurs through two processes: (i) hypertrophy, and (ii) hyperplasia, the formation of new adipocytes, also termed adipogen
Externí odkaz:
https://doaj.org/article/a0e714aa77284d4bad5b97fde188fa56
Autor:
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M. Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H. Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V. Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimiliano Mazzone, Sara Zanivan, Jan Cools, Hans Wildiers, Véronique Baud, Thomas G. P. Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
Publikováno v:
Nature Cancer. 4:344-364
Autor:
Patricia Altea-Manzano, Ginevra Doglioni, Alejandro M. Cuadros, Emma Nolan, Juan Fernandez-Garcia, Qi Wu, Florencia Cidre-Aranaz, Aurelie Montagne, Mélanie Planque, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Sofie Demeyer, Vincent Geldhof, Bram Boeckx, Alisa Alekseenko, Celia de la Calle Arregui, Giuseppe Floris, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimiliano Mazzone, Sara Zanivan, Jan Cools, Hans Wildiers, Véronique Baud, Thomas G.P. Grünewald, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
Cancer cells outgrowing in distant organs of metastasis rewire their metabolism to fuel on the available nutrients. While this is often considered an adaptive pressure limiting metastasis formation, some nutrients available at the metastatic site nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8515b57d510d955dab03c398615e6faa
https://doi.org/10.1101/2022.10.24.513556
https://doi.org/10.1101/2022.10.24.513556
Autor:
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M. Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, H. Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A. Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B. Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian M. L. Knott, Martin F. Orth, Sofie Demeyer, Guy Eelen, Lacey E. Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T. Lewis, Harald Bartsch, Manfred Wuhrer, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J. Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory J. Hannon, Sophia Y. Lunt, Thomas G. P. Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
Publikováno v:
Nature
Rossi, M, Altea-Manzano, P, Demicco, M, Doglioni, G, Bornes, L, Fukano, M, Vandekeere, A, Cuadros, A M, Fernández-García, J, Riera-Domingo, C, Jauset, C, Planque, M, Alkan, H F, Nittner, D, Zuo, D, Broadfield, L A, Parik, S, Pane, A A, Rizzollo, F, Rinaldi, G, Zhang, T, Teoh, S T, Aurora, A B, Karras, P, Vermeire, I, Broekaert, D, Elsen, J V, Knott, M M L, Orth, M F, Demeyer, S, Eelen, G, Dobrolecki, L E, Bassez, A, Brussel, T V, Sotlar, K, Lewis, M T, Bartsch, H, Wuhrer, M, Veelen, P V, Carmeliet, P, Cools, J, Morrison, S J, Marine, J C, Lambrechts, D, Mazzone, M, Hannon, G J, Lunt, S Y, Grünewald, T G P, Park, M, Rheenen, J V & Fendt, S M 2022, ' PHGDH heterogeneity potentiates cancer cell dissemination and metastasis ', Nature, vol. 605, no. 7911, pp. 747-753 . https://doi.org/10.1038/s41586-022-04758-2
Nature, 605(7911), 747-+. NATURE PORTFOLIO
Rossi, M, Altea-Manzano, P, Demicco, M, Doglioni, G, Bornes, L, Fukano, M, Vandekeere, A, Cuadros, A M, Fernández-García, J, Riera-Domingo, C, Jauset, C, Planque, M, Alkan, H F, Nittner, D, Zuo, D, Broadfield, L A, Parik, S, Pane, A A, Rizzollo, F, Rinaldi, G, Zhang, T, Teoh, S T, Aurora, A B, Karras, P, Vermeire, I, Broekaert, D, Elsen, J V, Knott, M M L, Orth, M F, Demeyer, S, Eelen, G, Dobrolecki, L E, Bassez, A, Brussel, T V, Sotlar, K, Lewis, M T, Bartsch, H, Wuhrer, M, Veelen, P V, Carmeliet, P, Cools, J, Morrison, S J, Marine, J C, Lambrechts, D, Mazzone, M, Hannon, G J, Lunt, S Y, Grünewald, T G P, Park, M, Rheenen, J V & Fendt, S M 2022, ' PHGDH heterogeneity potentiates cancer cell dissemination and metastasis ', Nature, vol. 605, no. 7911, pp. 747-753 . https://doi.org/10.1038/s41586-022-04758-2
Nature, 605(7911), 747-+. NATURE PORTFOLIO
Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs1. Genetic, transcriptional and translational heterogeneity contributes to this dynamic process2,3. Metabolic heterogeneity h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e5caca229c7c7298416a476ab4cc79
https://hdl.handle.net/1887/3480405
https://hdl.handle.net/1887/3480405
Autor:
Juan Fernández-García, Fabien Franco, Sweta Parik, Patricia Altea-Manzano, Antonino Alejandro Pane, Dorien Broekaert, Joke van Elsen, Giusy Di Conza, Ines Vermeire, Tessa Schalley, Mélanie Planque, Thomas van Brussel, Rogier Schepers, Elodie Modave, Tobias K. Karakach, Peter Carmeliet, Diether Lambrechts, Ping-Chih Ho, Sarah-Maria Fendt
Publikováno v:
Cell Reports
Fernández-García, J, Franco, F, Parik, S, Altea-Manzano, P, Pane, A A, Broekaert, D, van Elsen, J, Vermeire, I, Schalley, T, Planque, M, van Brussel, T, Schepers, R, Modave, E, Karakach, T K, Carmeliet, P, Lambrechts, D, Ho, P C & Fendt, S M 2022, ' CD8 + T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation ', Cell Reports, vol. 41, no. 7, 111639 . https://doi.org/10.1016/j.celrep.2022.111639
Fernández-García, J, Franco, F, Parik, S, Altea-Manzano, P, Pane, A A, Broekaert, D, van Elsen, J, Vermeire, I, Schalley, T, Planque, M, van Brussel, T, Schepers, R, Modave, E, Karakach, T K, Carmeliet, P, Lambrechts, D, Ho, P C & Fendt, S M 2022, ' CD8 + T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation ', Cell Reports, vol. 41, no. 7, 111639 . https://doi.org/10.1016/j.celrep.2022.111639
T cells dynamically rewire their metabolism during an immune response. We applied single-cell RNA sequencing to CD8+ T cells activated and differentiated in vitro in physiological medium to resolve these metabolic dynamics. We identify a differential
Autor:
Juan, Fernández-García, Fabien, Franco, Sweta, Parik, Patricia, Altea-Manzano, Antonino Alejandro, Pane, Dorien, Broekaert, Joke, van Elsen, Ines, Vermeire, Tessa, Schalley, Mélanie, Planque, Thomas, van Brussel, Rogier, Schepers, Elodie, Modave, Tobias K, Karakach, Peter, Carmeliet, Diether, Lambrechts, Ping-Chih, Ho, Sarah-Maria, Fendt
Publikováno v:
Cell reports. 41(7)
T cells dynamically rewire their metabolism during an immune response. We applied single-cell RNA sequencing to CD8
Autor:
Sarah-Maria Fendt, Peter Carmeliet, Rogier Schepers, Sweta Parik, Antonino Alejandro Pane, Juan Fernández-García, Fabien Franco, Tobias K. Karakach, Ping-Chih Ho, Dorien Broekaert, Joke Van Elsen, Ines Vermeire, Elodie Modave, Thomas Van Brussel, Diether Lambrechts
Cytotoxic T cells dynamically rewire their metabolism during the course of an immune response. While T-cell metabolism has been extensively studied at phenotypic endpoints of activation and differentiation, the underlying dynamics remain largely elus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81551b208900057b3f8feb8cdf0f083
https://doi.org/10.1101/2021.07.27.453976
https://doi.org/10.1101/2021.07.27.453976
Autor:
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M. Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, H. Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A. Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B. Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian M. L. Knott, Martin F. Orth, Sofie Demeyer, Guy Eelen, Lacey E. Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T. Lewis, Harald Bartsch, Manfred Wuhrer, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J. Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory J. Hannon, Sophia Y. Lunt, Thomas G. P. Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
Publikováno v:
Nature. 609:E8-E8
Autor:
Ines Vermeire, Ellen Vercalsteren, Max Gooijen, Ilse Scroyen, Christine Vranckx, Roger Lijnen
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 242-250 (2021)
Adipocyte
article-version (VoR) Version of Record
Adipocyte
article-version (VoR) Version of Record
Obesity, caused by an excess adipose tissue, is one of the biggest health-threats of the 21st century. Adipose tissue expansion occurs through two processes: (i) hypertrophy, and (ii) hyperplasia, the formation of new adipocytes, also termed adipogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6ccfc75098e9830dbd070a5bdf1919
https://lirias.kuleuven.be/handle/123456789/676971
https://lirias.kuleuven.be/handle/123456789/676971
Autor:
Alejandro M. Cuadros, Juan Fernández-Garcia, Mélanie Planque, Patricia Altea-Manzano, Tessa Schalley, Ines Vermeire, Dorien Broekaert, Qi Wu, Thomas Van Brussel, Sophia Leduc, Marion Maetens, Ha-Linh Nguyen, Karen Van Baelen, Naama Darzi, Giuseppe Floris, Hans Wildiers, Christine Desmedt, Diether Lambrechts, Sarah-Maria Fendt
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
SUMMARYMetastasizing cancer cells must adapt their metabolism to the nutrient environment of distant organs. We performed a loss-of-function CRISPR screen against Solute Carrier Transporters (SLCs) in a breast cancer mouse model to define nutrient re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd50375e81c677cfd101a87b9aac54f