Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ine Skottheim Rusten"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1281-1296 (2021)
Abstract Empirical pharmacometric models are part of practically every regulatory submission for a new drug. The use of the models often exceeds descriptory roles and this change in their context of use increase the requirements on the evidence to su
Externí odkaz:
https://doaj.org/article/22f9226774ba4d07af13a0fb0501d239
Autor:
Flora T. Musuamba, Ine Skottheim Rusten, Raphaëlle Lesage, Giulia Russo, Roberta Bursi, Luca Emili, Gaby Wangorsch, Efthymios Manolis, Kristin E. Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Cécile F. Rousseau, Emmanuelle M. Voisin, Rossana Alessandrello, Nuno Curado, Enrico Dall’ara, Blanca Rodriguez, Francesco Pappalardo, Liesbet Geris
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)
Abstract The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakehold
Externí odkaz:
https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1281-1296 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1281-1296 (2021)
Empirical pharmacometric models are part of practically every regulatory submission for a new drug. The use of the models often exceeds descriptory roles and this change in their context of use increase the requirements on the evidence to support tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1653016acf77948aaf139fddb357a4
http://europepmc.org/articles/PMC8592505
http://europepmc.org/articles/PMC8592505
Autor:
Cécile F. Rousseau, Kristin E. Karlsson, Raphaëlle Lesage, Eulalie Courcelles, Emmanuelle M. Voisin, Francesco Pappalardo, Nuno Curado, Enrico Dall'Ara, Flora T. Musuamba, Gaby Wangorsch, Blanca Rodriguez, Ine Skottheim Rusten, Rossana Alessandrello, Roberta Bursi, Giulia Russo, Luca Emili, Efthymios Manolis, Jean-Pierre Boissel, Liesbet Geris, Alexander Kulesza
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)
CPT: pharmacometrics & systems pharmacology, 10(8):804-825
CPT: Pharmacometrics & Systems Pharmacology
CPT: pharmacometrics & systems pharmacology, 10(8):804-825
CPT: Pharmacometrics & Systems Pharmacology
The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakeholders invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe3c36e4b9600157dcb89742acab793
https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde
https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde
Publikováno v:
International Journal of Pharmacokinetics. 2:113-124
Physiologically based pharmacokinetic (PBPK) models offer a mechanistic understanding of the disposition of the drug in the body. When well informed and conducted, this may lead to more efficient clinical studies in the vulnerable pediatric populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd31b1f10beb949509f77e5cefce209b
https://doi.org/10.4155/ipk-2016-0025
https://doi.org/10.4155/ipk-2016-0025
Autor:
Flora Musuamba Tshinanu, Frederike Lentz, Wei Zhao, Anna Karin Hamberg, Norbert Benda, Joseph F. Standing, Cecile Ollivier, Andrew Thomson, Sofia Friberg Hietala, Efthymios Manolis, Gérard Pons, Susan Cole, Paolo Tomasi, Ine Skottheim Rusten, María J. Garrido, Valeria Gigante, Ralf Herold, Anna Nordmark, Johannes Taminiau
Publikováno v:
Fundamentals of Pediatric Drug Dosing ISBN: 9783319437521
For a paediatric development to be rationally informed by all available knowledge, it is necessary to systematically collect and learn from available data, expert knowledge and prior developments. Aspects such as drug formulation, bioanalytical metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5211cde2b733f8349acdf1c43ee24f18
https://doi.org/10.1007/978-3-319-43754-5_7
https://doi.org/10.1007/978-3-319-43754-5_7
Autor:
Essam Kerwash, Frederike Lentz, Aris Dokoumetzidis, Joseph F. Standing, Flora T. Musuamba, Francesca Serone, Jacob Brogren, Susan Cole, Gaby Wangorsch, Anna Nordmark, Wei Zhao, Victor Mangas Sanjuan, Michiel van den Heuvel, David Khan, Gérard Pons, Johannes Taminiau, Norbert Benda, Justin L. Hay, Ine Skottheim Rusten, Kristin E. Karlsson, Valeria Gigante, Juha Vakkilainen, Efthymios Manolis
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:416-417
During the last 10 years the European Medicines Agency (EMA) organized a number of workshops on modeling and simulation, working towards greater integration of modeling and simulation (M&S) in the development and regulatory assessment of medicines. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e989839b91dbbbcc204868312c930c9
https://doi.org/10.1002/psp4.12223
https://doi.org/10.1002/psp4.12223