Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Inês Mendes Pinto"'
Autor:
Francisca Melo-Fonseca, Michael Gasik, Andrea Cruz, Daniel Moreira, Filipe S. Silva, Georgina Miranda, Inês Mendes Pinto
Publikováno v:
ACS Omega, Vol 9, Iss 8, Pp 8985-8994 (2024)
Externí odkaz:
https://doaj.org/article/b366285a5d414d428d75dc405c9b34cf
Autor:
Renato Socodato, Tiago O. Almeida, Camila C. Portugal, Evelyn C.S. Santos, Joana Tedim-Moreira, João Galvão-Ferreira, Teresa Canedo, Filipa I. Baptista, Ana Magalhães, António F. Ambrósio, Cord Brakebusch, Boris Rubinstein, Irina S. Moreira, Teresa Summavielle, Inês Mendes Pinto, João B. Relvas
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113447- (2023)
Summary: Microglia, the largest population of brain immune cells, continuously interact with synapses to maintain brain homeostasis. In this study, we use conditional cell-specific gene targeting in mice with multi-omics approaches and demonstrate th
Externí odkaz:
https://doaj.org/article/914f35ba494042d8aa265dd02cbdf0a4
Autor:
Vasco Rafael dos Santos, Victor Goncalves, Peishan Deng, Ana Cristina Ribeiro, Mariana Maia Teigao, Bárbara Dias, Inês Mendes Pinto, Juan Gallo, Weng Kung Peng
Publikováno v:
npj Science of Food, Vol 6, Iss 1, Pp 1-9 (2022)
Abstract Olive oil is one of the oldest and essential edible oils in the market. The classification of olive oils (e.g. extra virgin, virgin, refined) is often influenced by factors ranging from its complex inherent physiochemical properties (e.g. fa
Externí odkaz:
https://doaj.org/article/c3158e787d61433d9e6c25fcafce3065
Autor:
Pedro Melo, Renato Socodato, Mariana S. Silveira, Miguel António Dias Neves, João Bettencourt Relvas, Inês Mendes Pinto
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151247- (2022)
Microglia are the most prominent immune resident cell population in the central nervous system (CNS). In the healthy CNS, microglia survey their surrounding microenvironment, through recurrent extension and retraction of filopodia-like membrane protr
Externí odkaz:
https://doaj.org/article/89d1fa6c360143bb9df2111224a44a35
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/1104548dc235405cab602de4a5fbe4ed
Autor:
Ana Rita Costa, Sara C Sousa, Rita Pinto-Costa, José C Mateus, Cátia DF Lopes, Ana Catarina Costa, David Rosa, Diana Machado, Luis Pajuelo, Xuewei Wang, Feng-quan Zhou, António J Pereira, Paula Sampaio, Boris Y Rubinstein, Inês Mendes Pinto, Marko Lampe, Paulo Aguiar, Monica M Sousa
Publikováno v:
eLife, Vol 9 (2020)
Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and loss-of-function assays, we show that in rat hippocampal neurons the MPS is an actomyosin network that
Externí odkaz:
https://doaj.org/article/4602427c5eb7426abce176d9d2beeb7a
Publikováno v:
Life, Vol 11, Iss 8, p 816 (2021)
Stroke is a leading cause of death and disability in the world. To address such a problem, early diagnosis and tailored acute treatment represent one of the major priorities in acute stroke care. Since the efficacy of reperfusion treatments is highly
Externí odkaz:
https://doaj.org/article/ccde18c16183479a91d5365248f19fff
Autor:
Flávia Sousa, Andrea Cruz, Pedro Fonte, Inês Mendes Pinto, Maria Teresa Neves-Petersen, Bruno Sarmento
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Monoclonal antibodies have deserved a remarkable interest for more than 40 years as a vital tool for the treatment of various diseases. Still, there is a raising interest to develop advanced monoclonal antibody delivery systems able to tailo
Externí odkaz:
https://doaj.org/article/d53d29d91a274412b03b006cf9a016af
Autor:
Catarina M. Abreu, Ricardo Soares-dos-Reis, Pedro N. Melo, João B. Relvas, Joana Guimarães, Maria José Sá, Andrea P. Cruz, Inês Mendes Pinto
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Neuroinflammation plays a critical role in the onset and progression of many neurological disorders, including Multiple Sclerosis, Alzheimer's and Parkinson's diseases. In these clinical conditions the underlying neuroinflammatory processes are signi
Externí odkaz:
https://doaj.org/article/2a214eb7b4614ef49520c3a74a18978b
Autor:
Maria Vieira, Rosa Fernandes, António F. Ambrósio, Vanessa Cardoso, Mariana Carvalho, Peng Weng Kung, Miguel António Dias Neves, Inês Mendes Pinto
Publikováno v:
Lab on a Chip. 22:1876-1889
Diabetic retinopathy (DR) is the most common diabetic eye disease and the worldwide leading cause of vision loss in working-age adults. It progresses from mild to severe non-proliferative or proliferative DR based on several pathological features inc