Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Inês AM Barbosa"'
Autor:
M Joaquina Delás, Leah R Sabin, Egor Dolzhenko, Simon RV Knott, Ester Munera Maravilla, Benjamin T Jackson, Sophia A Wild, Tatjana Kovacevic, Eva Maria Stork, Meng Zhou, Nicolas Erard, Emily Lee, David R Kelley, Mareike Roth, Inês AM Barbosa, Johannes Zuber, John L Rinn, Andrew D Smith, Gregory J Hannon
Publikováno v:
eLife, Vol 6 (2017)
A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis a
Externí odkaz:
https://doaj.org/article/e9c2590fa9734ed099eb3c9e83222b6f
Autor:
Robert S. Welner, Ann-Sofie Schmolke, Florian Grebien, Christoph Kornauth, John Anto Pulikkan, Bon Q. Trinh, Katrina Vanura, Wolfgang R. Sperr, Angelika Pichler, A Di Ruscio, Ruud Delwel, Elizabeth Heyes, Johannes Zuber, Inês Am Barbosa, Akos Czibere, Heinz Sill, Karin Lind, Lukas Kazianka, J. Klinger, Maurizio Forte, Peter Valent, Gerwin Heller, Lucio H. Castilla, Alex Ebralidze, Philipp B. Staber, Daniel G. Tenen, E. van der Kouwe, Trang Le, C. M. Schweicker, Andreas Spittler, Tea Pemovska, C. Agreiter, S. Surapally
Publikováno v:
Blood, 138(15), 1345-1358. American Society of Hematology
The blood system serves as a key model for cell differentiation and cancer. It is orchestrated by precise spatiotemporal expression of crucial transcription factors. One of the key master regulators in the hematopoietic systems is PU.1. Reduced level
Autor:
Alexander Pichler, Gerwin Heller, Emiel van der Kouwe, Akos Czibere, Alexander K. Ebralidze, Heinz Sill, Peter Valent, Bon Q. Trinh, Maurizio Forte, Philipp B. Staber, Wolfgang R. Sperr, Trang Le, John Anto Pulikkan, Andreas Spittler, Lukas Kazianka, Daniel G. Tenen, Karin Lind, Ann-Sofie Schmolke, Robert S. Welner, Johannes Zuber, Katrina Vanura, Lucio H. Castilla, Inês Am Barbosa, Annalisa Di Ruscio, Christoph Kornauth, Ruud Delwel
Publikováno v:
Blood. 136:40-41
Introduction: Alterations of core binding factors (CBF), Runx1 and CBFβ are frequent mutational targets in acute myeloid leukemia (AML). Chromosomal translocations t(8;21)(q22;q22) and inv(16)(p13q22), creating the fusion proteins RUNX1-ETO and CBF
Autor:
Yong Yu, Inês Am Barbosa, Katharina Pardon, Andreas Trumpp, Dimitri Belenki, Hinrich Gronemeyer, Dorothy N. Y. Fan, Jan Dörr, Marco A. Mendoza-Parra, Maja Milanovic, Lora Dimitrova, Maurice Reimann, Marlen Metzner, Zhen Zhao, Tamara Kanashova, Dido Lenze, Clemens A. Schmitt, J. Henry M. Däbritz, Soyoung Lee, Michael Hummel, Johannes Zuber, Bernd Dörken, Gunnar Dittmar
Publikováno v:
Nature
Nature, Nature Publishing Group, 2018, 553 (7686), pp.96-100. ⟨10.1038/nature25167⟩
Nature, Nature Publishing Group, 2018, 553 (7686), pp.96-100. ⟨10.1038/nature25167⟩
Cellular senescence is a stress-responsive cell-cycle arrest program that terminates the further expansion of (pre-)malignant cells. Key signalling components of the senescence machinery, such as p16(INK4a), p21(CIP1) and p53, as well as trimethylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5693bfb1cf0313dd752edd8c15b9dce4
https://hal.archives-ouvertes.fr/hal-02364397
https://hal.archives-ouvertes.fr/hal-02364397
Autor:
Andrew D. Smith, David R. Kelley, Ester Munera Maravilla, Leah R. Sabin, Nicolas Erard, John L. Rinn, M. Joaquina Delás, Mareike Roth, Gregory J. Hannon, Tatjana Kovacevic, Johannes Zuber, Benjamin T Jackson, Sophia A Wild, Emily Lee, Egor Dolzhenko, Meng Zhou, Simon R.V. Knott, Eva Maria Stork, Inês Am Barbosa
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis a
Autor:
Jung Shick Kwon, Vaishali Sridhar, Mareike Roth, Nishi Sinha, Johannes Zuber, Christof Fellmann, Dan Yu Lai, Yuanzhe Guan, Inês Am Barbosa, Matthias Muhar, Barbara Hopfgartner, Thomas Hoffmann
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1704-1713 (2013)
SummaryShort hairpin RNA (shRNA) technology enables stable and regulated gene repression. For establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs can be embedded into endogenous microRNA contexts. However, due