Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Induced hepatocytes"'
Autor:
Rombaut, Matthias 1, ∗, Boeckmans, Joost 1, Rodrigues, Robim M. 1, van Grunsven, Leo A. 2, Vanhaecke, Tamara 1, De Kock, Joery 1, ∗
Publikováno v:
In Journal of Hepatology September 2021 75(3):690-705
Autor:
Imran Ullah, Yurianna Shin, Yeongji Kim, Keon Bong Oh, Seongsoo Hwang, Young-Im Kim, Jeong Woong Lee, Tai-Young Hur, Seunghoon Lee, Sun A Ock
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background The liver is one of the vital organs involved in detoxification and metabolism. The sex-based differences between the functionality of male and female liver have been previously reported, i.e., male’s liver are good in alcohol c
Externí odkaz:
https://doaj.org/article/b4e4ec9984e54b4c97b29d05a8651538
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background The development of somatic reprogramming, especially purely chemical reprogramming, has significantly advanced biological research. And chemical-induced extraembryonic endoderm-like (ciXEN) cells have been confirmed to be an indis
Externí odkaz:
https://doaj.org/article/c3c58903cbe44c5fbf00bf58d614c9d4
Autor:
Yan Li, Ying-Yuan Lu, Jun Jia, Meng Fang, Lin Zhao, Yong Jiang, Yan Shi, Peng-Fei Tu, Xiao-Yu Guo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Cytochrome P450 (CYP) is the most important phase I drug-metabolizing enzyme, and the effect of drugs on CYP enzymes can lead to decreased pharmacological efficacy or enhanced toxicity of drugs, but there are many deficiencies in the evaluation model
Externí odkaz:
https://doaj.org/article/e580dfb2db214744991bd7d8869f579c
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Kyung Tae Lim, Seung Chan Lee, Yimeng Gao, Kee-Pyo Kim, Guangqi Song, Su Yeon An, Kenjiro Adachi, Yu Jin Jang, Jonghun Kim, Kyoung-Jin Oh, Tae Hwan Kwak, Seon In Hwang, Jueng Soo You, Kinarm Ko, Seung-Hoi Koo, Amar Deep Sharma, Jong-Hoon Kim, Lijian Hui, Tobias Cantz, Hans R. Schöler, Dong Wook Han
Publikováno v:
Cell Reports, Vol 15, Iss 4, Pp 814-829 (2016)
Recent studies have shown that defined factors could lead to the direct conversion of fibroblasts into induced hepatocyte-like cells (iHeps). However, reported conversion efficiencies are very low, and the underlying mechanism of the direct hepatic r
Externí odkaz:
https://doaj.org/article/3bb0855578b848449a9046f2debd0690
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Leo A. van Grunsven, Joery De Kock, Matthias Rombaut, Tamara Vanhaecke, Joost Boeckmans, Robim Marcelino Rodrigues
Summary There is an unmet need for functional primary human hepatocytes to support the pharmaceutical and (bio)medical demand. The unique discovery, a decade ago, that somatic cells can be drawn out of their apparent biological lockdown to reacquire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83f8e39e331c11e1afd602f3bb8ef15
https://biblio.vub.ac.be/vubir/(add37840-d18e-4ecf-8929-eb9031c60017).html
https://biblio.vub.ac.be/vubir/(add37840-d18e-4ecf-8929-eb9031c60017).html
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Background The development of somatic reprogramming, especially purely chemical reprogramming, has significantly advanced biological research. And chemical-induced extraembryonic endoderm-like (ciXEN) cells have been confirmed to be an indispensable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943654ec98071e7e9c17ec0e6a32710d
https://doi.org/10.1186/s13287-020-01664-0
https://doi.org/10.1186/s13287-020-01664-0
Autor:
Seunghoon Lee, Yeongji Kim, Jeong Woong Lee, Seongsoo Hwang, Yurianna Shin, Imran Ullah, Tai-Young Hur, Youngim Kim, Sun A Ock, Keon Bong Oh
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Background The liver is one of the vital organs involved in detoxification and metabolism. The sex-based differences between the functionality of male and female liver have been previously reported, i.e., male’s liver are good in alcohol clearance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a3cc6cc6fd9c9abb16f056ca98120
https://doi.org/10.21203/rs.3.rs-17849/v1
https://doi.org/10.21203/rs.3.rs-17849/v1