Uracil as a biomarker for spatial pyrimidine metabolism in the development of gingivobuccal oral squamous cell carcinoma

Autor: Soni Shaikh, Sangramjit Basu, Swarnendu Bag, Ankita Chatterjee, Sourav Datta, Devmalya Banerjee, Kapila Manikantan, Indu Arun, Pattatheyil Arun, Nidhan K. Biswas, Arindam Maitra, Deepak Kumar Mishra, Partha P. Majumder, Harsh Dhar, Geetashree Mukherjee

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract No biomarker has yet been identified that allows accurate diagnosis and prognosis of oral cancers. In this study, we investigated the presence of key metabolites in oral cancer using proton nuclear magnetic resonance (NMR) spectroscopy to id

Externí odkaz: https://doaj.org/article/19d770861f894c77b292c914d66b43d6

Overexpression of CD73 is associated with recurrence and poor prognosis of gingivobuccal oral cancer as revealed by transcriptome and deep immune profiling of paired tumor and margin tissues

Autor: Ankita Chatterjee, Amrita Chaudhary, Arnab Ghosh, Pattatheyil Arun, Geetashree Mukherjee, Indu Arun, Arindam Maitra, Nidhan Biswas, Partha P. Majumder

Publikováno v: Cancer Medicine, Vol 12, Iss 16, Pp 16774-16787 (2023)

Abstract Background For various cancers, differences in response to treatment and subsequent survival period have been reported to be associated with variation in immune contextures. Aim We sought to identify whether such association exists in respec

Externí odkaz: https://doaj.org/article/3384f9e7ca7549e4b45b9511a58a7056

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Autor: Khalid El Bairi, Harry R. Haynes, Elizabeth Blackley, Susan Fineberg, Jeffrey Shear, Sophia Turner, Juliana Ribeiro de Freitas, Daniel Sur, Luis Claudio Amendola, Masoumeh Gharib, Amine Kallala, Indu Arun, Farid Azmoudeh-Ardalan, Luciana Fujimoto, Luz F. Sua, Shi-Wei Liu, Huang-Chun Lien, Pawan Kirtani, Marcelo Balancin, Hicham El Attar, Prerna Guleria, Wenxian Yang, Emad Shash, I-Chun Chen, Veronica Bautista, Jose Fernando Do Prado Moura, Bernardo L. Rapoport, Carlos Castaneda, Eunice Spengler, Gabriela Acosta-Haab, Isabel Frahm, Joselyn Sanchez, Miluska Castillo, Najat Bouchmaa, Reena R. Md Zin, Ruohong Shui, Timothy Onyuma, Wentao Yang, Zaheed Husain, Karen Willard-Gallo, An Coosemans, Edith A. Perez, Elena Provenzano, Paula Gonzalez Ericsson, Eduardo Richardet, Ravi Mehrotra, Sandra Sarancone, Anna Ehinger, David L. Rimm, John M. S. Bartlett, Giuseppe Viale, Carsten Denkert, Akira I. Hida, Christos Sotiriou, Sibylle Loibl, Stephen M. Hewitt, Sunil Badve, William Fraser Symmans, Rim S. Kim, Giancarlo Pruneri, Shom Goel, Prudence A. Francis, Gloria Inurrigarro, Rin Yamaguchi, Hernan Garcia-Rivello, Hugo Horlings, Said Afqir, Roberto Salgado, Sylvia Adams, Marleen Kok, Maria Vittoria Dieci, Stefan Michiels, Sandra Demaria, Sherene Loi, The International Immuno-Oncology Biomarker Working Group

Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)

Abstract The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of pr

Externí odkaz: https://doaj.org/article/98d18f7227c34bcb8909cccb39302c30

Management of Tomato Damping-off Disease in the Nursery Using of Trichoderma asperellum

Autor: Kishor Chand Kumhar, Kuldeep Kumar, Indu Arora, Arun Kumar Bhatia, Vinod Kumar Batra, Hans Raj

Publikováno v: International Journal of Economic Plants, Vol 9, Iss May, 2 (2022)

The study was conducted during 2018−19 and 2019−20 to evaluate effectiveness of the Trichoderma asperellum liquid formulation for the management of tomato damping-off in the nursery. The experiment was conducted for two consecutive seasons in a r

Externí odkaz: https://doaj.org/article/cf582413c6a146e5ae10f30d05d7d02d

Relapsed Refractory Hodgkin Lymphoma and Brentuximab Vedotin-Bendamustine Combination Therapy as a Bridge to Transplantation: Real-World Evidence From a Middle-Income Setting and Literature Review

Autor: Vivek S. Radhakrishnan, Rajat Bajaj, Vasundhara Raina, Jeevan Kumar, Saurabh J. Bhave, Reghu K. Sukumaran Nair, Arijit Nag, Indu Arun, Lateef Zameer, Debdeep Dey, Neeraj Arora, Mayur Parihar, Jayanta Das, Rimpa B. Achari, Deepak K. Mishra, Mammen Chandy, Reena Nair

Publikováno v: Frontiers in Oncology, Vol 11 (2022)

IntroductionDespite high cure rates with standard treatment, 30% patients with Hodgkin lymphoma develop relapsed or refractory (R/R) disease. Salvage therapy followed by autologous hematopoietic cell transplantation (HCT) is considered standard of ca

Externí odkaz: https://doaj.org/article/dae1e4f52afa48cfae5a870c4b097c72