Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Indrek Teino"'
Autor:
Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA int
Externí odkaz:
https://doaj.org/article/50205bb260684d2cbb3e422b4eefcc20
Autor:
Ljudmila Klepinina, Aleksandr Klepinin, Laura Truu, Vladimir Chekulayev, Heiki Vija, Kaisa Kuus, Indrek Teino, Martin Pook, Toivo Maimets, Tuuli Kaambre
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245348 (2021)
The ability of butyrate to promote differentiation of cancer cells has important implication for colorectal cancer (CRC) prevention and therapy. In this study, we examined the effect of sodium butyrate (NaBT) on the energy metabolism of colon adenoca
Externí odkaz:
https://doaj.org/article/4bdc7c2e72e34189ac95531ad5bdfcc0
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138346 (2015)
Laminin isoforms laminin-511 and -521 are expressed by human embryonic stem cells (hESC) and can be used as a growth matrix to culture these cells under pluripotent conditions. However, the expression of these laminins during the induction of hESC di
Externí odkaz:
https://doaj.org/article/c95b2c9357f64e6a9002648ef8ce9930
Autor:
Simona Selberg, Larisa Ivanova, Mihkel Kotli, Koit Herodes, Daria Blokhina, Esko Kankuri, Neinar Seli, Ivar Ilves, Indrek Teino, Mart Saarma, Mati Karelson
The overexpression of RNA 6-N-methyladenosine (m6A) methyltransferase METTL16 has oncogenic role in the case of several cancer types, including leukemia, but efficient small-molecule inhibitors are not available. Initially identified by high-throughp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a2fecc72d5802043778108511114e9
https://doi.org/10.1101/2023.03.27.534333
https://doi.org/10.1101/2023.03.27.534333
Autor:
Arnold Kristjuhan, Helen Vaher, Annika Trei, Inge Varik, Tõnis Org, Laura Pajusaar, Toivo Maimets, Indrek Teino, Antti Matvere, Martin Pook, Keyt Uudeküll
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9052, p 9052 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9052, p 9052 (2020)
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor, which mediates the effects of a variety of environmental stimuli in multiple tissues. Recent advances in AHR biology have underlined its importance in cells with high develop
Autor:
Martin Pook, Annika Trei, Egle-Helene Ervin, Indrek Teino, Valmar Kasuk, Margus Pooga, Toivo Maimets
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference
Autor:
Kalju Paju, Indrek Teino, Sulev Kõks, Lyudmila Ounpuu, Igor Shevchuk, Aleksandr Klepinin, Tuuli Kaambre, Vladimir Chekulayev, Martin Pook, Nadezda Peet, Toivo Maimets, Kersti Tepp
Publikováno v:
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Recent studies have shown that cellular bioenergetics may be involved in stem cell differentiation. Considering that during cancerogenesis cells acquire numerous properties of stem cells, it is possible to assume that the energy metabolism in tumorig
Autor:
Tarmo Tiido, Indrek Teino, Arnold Kristjuhan, Sulev Kuuse, Toivo Maimets, Antti Matvere, Inge Varik
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3068 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences
Volume 20
Issue 12
The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor primarily known for its toxicological functions. Recent studies have established its importance in many physiological processes including female reproduction, although the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0138346 (2015)
PLoS ONE, Vol 10, Iss 9, p e0138346 (2015)
Laminin isoforms laminin-511 and -521 are expressed by human embryonic stem cells (hESC) and can be used as a growth matrix to culture these cells under pluripotent conditions. However, the expression of these laminins during the induction of hESC di
Autor:
Tarmo Tiido, Toivo Maimets, Antti Matvere, Indrek Teino, Sulev Kuuse, Sulev Ingerpuu, Arnold Kristjuhan
Publikováno v:
Molecular and cellular endocrinology. 382(1)
Recent advances in establishing the role of the aryl hydrocarbon receptor (Ahr) in normophysiology have discovered its fundamental role, amongst others, in female reproduction. Considering previous studies suggesting the hormonal modulation of Ahr, w