Výsledky vyhledávání - "Indre Augustinaite"

A Quantitative High-Throughput Screen Identifies Novel Inhibitors of the Interaction of Thyroid Receptor β with a Peptide of Steroid Receptor Coactivator 2

Autor: Ruili Huang, Leggy A. Arnold, Ronald L. Johnson, Jong Yeon Hwang, R. Kiplin Guy, Wenwei Huang, Indre Augustinaite, Jennifer Wichterman, James Inglese, Christopher P. Austin

Publikováno v: SLAS Discovery. 16:618-627

The thyroid hormone receptors (TR) are members of the nuclear hormone receptor (NHR) superfamily that regulate development, growth, and metabolism. Upon ligand binding, TR releases bound corepressors and recruits coactivators to modulate target gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575de96bfa254b127b4bf70b6ce14038
https://doi.org/10.1177/1087057111402199

Zobrazit plný text záznamu

Methylsulfonylnitrobenzoates, a New Class of Irreversible Inhibitors of the Interaction of the Thyroid Hormone Receptor and Its Obligate Coactivators That Functionally Antagonizes Thyroid Hormone

Autor: Ramy R. Attia, Wenwei Huang, James Inglese, Michele Connelly, Leggy A. Arnold, Jong Yeon Hwang, Ruili Huang, Jennifer Wichterman, Ronald L. Johnson, Indre Augustinaite, R. Kiplin Guy, Christopher P. Austin, Fangyi Zhu

Publikováno v: Journal of Biological Chemistry. 286:11895-11908

Thyroid hormone receptors (TRs) are members of the nuclear hormone receptor (NR) superfamily and regulate development, growth, and metabolism. Upon binding thyroid hormone, TR undergoes a conformational change that allows the release of corepressors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b8dabe92b34c5a5ae7fd6b83c50e75
https://doi.org/10.1074/jbc.m110.200436

Zobrazit plný text záznamu

Quantification of the Vitamin D Receptor−Coregulator Interaction

Autor: R. Kiplin Guy, Daniel D. Bikle, Tim R. Geistlinger, Steve Otieno, Yuko Oda, Indre Augustinaite, Richard W. Kriwacki, Leggy A. Arnold, Arnaud Teichert

Publikováno v: Biochemistry. 48:1454-1461

The vitamin D receptor (VDR) regulates a diverse set of genes that control processes including bone mineral homeostasis, immune function, and hair follicle cycling. Upon binding to its natural ligand, 1alpha,25(OH)(2)D(3), the VDR undergoes a conform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7025458158870144ba9b5a2393b7f2
https://doi.org/10.1021/bi801874n

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání