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pro vyhledávání: '"Indrani Woollam"'
Autor:
Graham Anthony Charles Frampton, Indrani Woollam, Ruth B. Katz, Ian Harold Smith, Neil Tremayne, Duncan Hannah, Robert John Watson, Neil Henderson
Publikováno v:
Organic Process Research & Development. 8:415-417
The synthesis of the matrix metalloproteinase (MMP) inhibitor CH8757 is described. The discovery route has been modified to incorporate a three-stage one-pot sequence using α,α,α-trifluorotoluene as solvent. The formation of the hydroxamic acid us