Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Indraneel Ghosh"'
Autor:
Indranil Mukhopadhyay, Abhay Kulkarni, Sarika Aranake, Pallavi Karnik, Mahesh Shetty, Sandeep Thorat, Indraneel Ghosh, Dinesh Wale, Vikram Bhosale, Neelima Khairatkar-Joshi
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97005 (2014)
Cough is a protective reflex action that helps clear the respiratory tract which is continuously exposed to airborne environmental irritants. However, chronic cough presents itself as a disease in its own right and despite its global occurrence; the
Externí odkaz:
https://doaj.org/article/d053a7409087492fbb26ad6c5d9bc3fe
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 4 (2010)
Platelet-activating factor acetylhydrolase 1B (PAF-AH) inactivates the potent phospholipid platelet-activating factor (PAF) and is composed of two catalytic subunits (α1 and α2) and a dimeric regulatory subunit, LIS1. The function of the catalytic
Externí odkaz:
https://doaj.org/article/773972ad8ea44ca9b308583930802d8c
Autor:
Natasha R. Cornejo, Bismark Amofah, Austin Lipinski, Paul R. Langlais, Indraneel Ghosh, John C. Jewett
Publikováno v:
Biochemistry
A challenge within the field of bioconjugation is developing probes to uncover novel information on proteins and other biomolecules. Intracellular delivery of these probes offers the promise of giving relevant context to this information, and these p
Autor:
Natasha R. Cornejo, Bismark Amofah, Austin Lipinski, Paul R. Langlais, Indraneel Ghosh, John C. Jewett
Publikováno v:
Biochemistry. 61:1531-1531
Publikováno v:
ICOIN
Command-and-Control (C&C) servers use Domain Generation Algorithms (DGAs) to communicate with bots for uploading malware and coordinating attacks. Manual detection methods and sinkholing fail to work against these algorithms, which can generate thous
Autor:
Amol Magdum, Anil Panmand, Ravi K. Bhamidipati, Amol A. Raje, Vamsi Madgula, Ganesh Bhat, Meena Patel, Sreekanth R. Rouduri, Siddhartha De, Yogesh D. Shejul, Rajesh Bonagiri, Vandna Prasad, Anita Chugh, Ashwinkumar V. Meru, Vidya Ramdas, Sujay Basu, Dinesh A. Barawkar, Venkata P. Palle, Azfar Quraishi, Narayanan Hariharan, Sumit Chaudhary, Kasim A. Mookhtiar, Indraneel Ghosh, Minakshi Naykodi, K. Kashinath, Sachin Thorat
Publikováno v:
ACS Medicinal Chemistry Letters. 8:835-840
Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the therapeutic potential of 7-methoxy-4-morpholino-benzothiazole derivatives as A2AAdoR ant
Autor:
Azfar Quraishi, Abhay Kulkarni, Vidya Ramdas, Sreekanth R. Rouduri, Sujay Basu, Yogesh Waman, Vaibhav Jain, Anil Panmand, Vandna Prasad, Arnab Goswami, Sachin Thorat, Meena Patel, Anita Chugh, Santosh Kumar, B. Srinivasa Reddy, Syed Mustafa, Sandhya Chaturvedi, Kasim A. Mookhtiar, Siddhartha De, Ena Ray Banerjee, Suraj Menon, Minakshi Naykodi, Shalini Paliwal, Venkata P. Palle, Vikas Karande, Indraneel Ghosh, Dinesh A. Barawkar
Publikováno v:
European Journal of Medicinal Chemistry. 134:218-229
Adenosine induces bronchial hyperresponsiveness and inflammation in asthmatics through activation of A2B adenosine receptor (A2BAdoR). Selective antagonists have been shown to attenuate airway reactivity and improve inflammatory conditions in pre-cli
Autor:
Venkata P. Palle, Dinesh A. Barawkar, Vandna Prasad, Santosh Kumar, Sachin Thorat, Sreekanth R. Rouduri, Sushant Dusange, Yogesh Waman, Arnab Goswami, Anita Chugh, B. Srinivasa Reddy, Kasim A. Mookhtiar, Anil Panmand, Gaurav Bedse, Rajesh Bonagiri, Azfar Quraishi, Vikas Karande, Vidya Ramdas, Meena Patel, Indraneel Ghosh, Rhishikesh Thakre, Sujay Basu, Shalini Paliwal, Dilip Jadhav, Sandhya Chaturvedi, Partha P. Mukhopadhyay, Abhay Kulkarni, Jayasagar Gundu, Suraj Menon
Publikováno v:
European Journal of Medicinal Chemistry. 127:986-996
A2BAdoR is a low affinity adenosine receptor that functions by Gs mediated elevation of cAMP and subsequent downstream signaling. The receptor has been implicated in lung inflammatory disorders like COPD and asthma. Several potent and selective A2BAd
Autor:
Azfar Quraishi, Anita Chug, Suraj Menon, Vishal Unadkat, Sujay Basu, Madhav S. Seervi, Vandna Prasad, Sumit Chaudhary, Yogesh D. Shejul, Ganesh Bhat, Sachin Thorat, Ravi K. Bhamidipati, Shariq S. Ansari, Ashwinkumar V. Meru, Rhishikesh Thakare, Kasim A. Mookhtiar, Yogesh Salve, Venkata P. Palle, Minakshi Naykodi, Siddhartha De, Vaibhav Jain, Harish Patil, Indraneel Ghosh, Dinesh A. Barawkar, Meena Patel, Sreekanth R. Rouduri
Publikováno v:
Journal of Medicinal Chemistry. 60:681-694
Our initial structure–activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A2A adenosine
Publikováno v:
The FASEB Journal. 32