Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Indracanti Prem Kumar"'
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 18-25 (2017)
Background: The lack of a safe and effective drug against radiation injury is a major hurdle in management of these diseases. Owing to unprecedented radionuclear threats and accidents that may occur, screening of Johns Hopkins Clinical Compound Libra
Externí odkaz:
https://doaj.org/article/8fa741f97cf44bdfa407965b12d74f67
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 18-25 (2017)
Background The lack of a safe and effective drug against radiation injury is a major hurdle in management of these diseases. Owing to unprecedented radionuclear threats and accidents that may occur, screening of Johns Hopkins Clinical Compound Librar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5128de3db9c830db03ec5cc65b22f8
https://doi.org/10.1016/j.imu.2017.05.007
https://doi.org/10.1016/j.imu.2017.05.007
Autor:
Rina Chakraborti, Neeta Sehgal, Jayadev Joshi, Subhajit Ghosh, Nitisha Shrivastava, Jharna Ray, Manali Dimri, Indracanti Prem Kumar
Publikováno v:
Current Computer Aided-Drug Design. 11:222-236
Ligand bound beta 2 adrenergic receptor (β2AR) crystal structures are in use for screening of compound libraries for identifying inducers and blockers. However, in case of G protein coupled receptors (GPCR), docking and binding energy (BE) calculati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fabcf40470089cf13c29ea2c857986b
https://doi.org/10.2174/1573409911666150812130420
https://doi.org/10.2174/1573409911666150812130420
Autor:
Indracanti Prem Kumar, Manali Dimri, Angara Sureshbabu, Rina Chakrabarti, Neeta Sehgal, Jayadev Joshi
Publikováno v:
Zebrafish. 12:33-47
The Johns Hopkins Clinical Compound Library (JHCCL), a collection of Food and Drug Administration (FDA)-approved small molecules (1400), was screened in silico for identification of novel β2AR blockers and tested for hematopoietic stem cell (HSC) ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5af5c145e6f9bccbbe4f7b8f8e9476
https://doi.org/10.1089/zeb.2014.0992
https://doi.org/10.1089/zeb.2014.0992
Publikováno v:
Defence Science Journal. 61:146-156
Appropriate models are essential for making the transition from scientific discoveries to meaningful applications of the knowledge for human use. Acute as well as delayed effects of ionising radiation to the biological systems develop hierarchically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9650ce9f4b8f7dffa90350674125f1
https://doi.org/10.14429/dsj.61.835
https://doi.org/10.14429/dsj.61.835
Autor:
Rajendra P. Tripathi, M. Memita Devi, Poonam Rana, Salim Javed, Subash Khushu, Ritu Tyagi, Ahmad Raza Khan, Indracanti Prem Kumar
Publikováno v:
Metabolomics. 7:583-592
Radiation accidents are rare events that induce radiation syndrome, a complex pathology which is difficult to treat. In medical management of radiation victims, life threatening damage to different physiological systems should be taken into considera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c1e5f18b840219bd0055f01278231fe
https://doi.org/10.1007/s11306-011-0277-4
https://doi.org/10.1007/s11306-011-0277-4
Autor:
S. C. Puri, Rakesh Sharma, Ghulam Nabi Qazi, Sandeep Kumar Shukla, Indracanti Prem Kumar, Pankaj Chaudhary, Farhat Afrin
Publikováno v:
Environmental Toxicology and Pharmacology. 22:113-120
Podophyllum hexandrum , a herb thriving in Himalayas has already been reported to exhibit antitumor and radioprotective properties. Present study was undertaken to unravel the possible mechanism responsible for the cytotoxic and radioprotective prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1331aa3d6b85f2a5b4323cd047e85f
https://doi.org/10.1016/j.etap.2006.01.001
https://doi.org/10.1016/j.etap.2006.01.001
Autor:
Arun K. Sinha, Pankaj Chaudhary, Farhat Afrin, Manju Lata Gupta, Rakesh Sharma, Yogendra Kumar Sharma, Sandeep Kumar Shukla, Indracanti Prem Kumar, Upendra K. Sharma, Namita Samanta
Publikováno v:
Environmental and Molecular Mutagenesis. 47:647-656
Hippophae rhamnoides or seabuckthorn is used extensively in Indian and Tibetan traditional medicine for the treatment of circulatory disorders, ischemic heart disease, hepatic injury, and neoplasia. In the present study, we have evaluated the radiopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bcf2765e93eff379837125bb0d8a39
https://doi.org/10.1002/em.20251
https://doi.org/10.1002/em.20251
Autor:
Rahul Shubhra Mandal, Tapan Kumar Barik, Srinivasan Ramachandran, Indracanti Prem Kumar, Manali Dimri, Subhajit Ghosh, Nitisha Shrivastava, Jayadev Joshi
Publikováno v:
Current computer-aided drug design. 9(1)
Cyclooxygenase-2 (COX-2) is well established for its role in inflammation, cancer and has also been reported to play a significant role in radiation induced inflammation and bystander effect. It has already been reported to have a role in protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e270bd90ed3ba5154e3dae27c5668da8
https://pubmed.ncbi.nlm.nih.gov/23905928
https://pubmed.ncbi.nlm.nih.gov/23905928
Autor:
Sung-Cheng Huang, Koon-Pong Wong, Indracanti Prem Kumar, Donna Frances Kusewitt, Hidevaldo B. Machado, Susan M. Fischer, Harvey R. Herschman, Tomo-o Ishikawa
Many tumor cells have elevated rates of glucose uptake that can be measured quantitatively, noninvasively and repeatedly by positron emission tomography (PET) with 2-deoxy-2-[ 18 F]-fluoro-D-glucose ( 18 F-FDG). Clinical imaging with 18 F-FDG PET has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78382fe4ee955f9b5984e1198f2090f2
https://europepmc.org/articles/PMC2838935/
https://europepmc.org/articles/PMC2838935/
