Výsledky vyhledávání - "Indomethacin/pharmacology"

Akademický článek

Protective Effect of Indomethacin-loaded Polymeric Nanoparticles Against Oxidative Stress-Induced Cytotoxicity in Human Breast Adenocarcinoma Cell Model

Autor: Camila Franco, Altevir Rossato Viana, Aline Ferreira Ourique, Bruno Stefanello Vizzotto, Luciana Maria Fontanari Krause

Publikováno v: Revista Brasileira de Cancerologia, Vol 68, Iss 4 (2022)

Introduction: Anti-inflammatory drugs are being utilized to treat cancer because of its inflammatory microenvironment. Objective: The objective of this study is to investigate the antioxidant potential of indomethacin and its genotoxicity, since free

Externí odkaz: https://doaj.org/article/615327c9afef40fa98af1bf18af1fdef

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Anti-inflammatory agents and inducibility of hepatic drug metabolism

Autor: P. Stephanou, Periklis Pappas, Marios Marselos, Vasilis Vasiliou

Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 23:457-460

Two rat liver cytosolic aldehyde dehydrogenases, ALDH1 and ALDH3c, are of particular interest because they are inducible by different classes of xenobiotics. ALDHI is mainly increased by phenobarbital-type inducers; polycyclic aromatic hydrocarbons (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4156f8b5b1b6ece676c889e7faf3c5b8
https://doi.org/10.1007/bf03189995

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Enhanced protein denaturation in indomethacin-treated cells

Autor: Olivier Bensaude, Gerassimos N. Pagoulatos, Van Trung Nguyen, I. Roussou

Indomethacin, a potent anti-inflammatory drug, activates the DNA-binding activity of human heat shock transcription factor 1 (HSF1), but this is insufficient to elevate heat shock gene expression. However, indomethacin pretreatment leads to a complet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e109912aa7db90fcbce8143d0ce272
https://europepmc.org/articles/PMC312904/

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Pharmacological modulation of heat shock factor 1 by antiinflammatory drugs results in protection against stress-induced cellular damage

Autor: Lee, B. S., Chen, J., Angelidis, C., Jurivich, D. A., Morimoto, R. I.

The activation of heat shock genes by diverse forms of environmental and physiological stress has been implicated in a number of human diseases, including ischemic damage, reperfusion injury, infection, neurodegeneration, and inflammation. The enhanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::301a8aa5c444bb9328becf4fe826f5fb
http://olympias.lib.uoi.gr/jspui/handle/123456789/19335

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An interleukin 1 receptor antagonist blocks the IL-1-induced IL-6 paracrine production through a prostaglandin E2-related mechanism in multiple myeloma

Autor: Z Y, Lu, R, Bataille, P, Poubelle, M J, Rapp, J L, Harousseau, B, Klein

Publikováno v: STEM CELLS
STEM CELLS, AlphaMed Press, 1995, 13 Suppl 2, pp.28--34

By analogy with the model of pristane-induced mouse plasmacytomas, we have wondered about the putative role of prostaglandin E2 (PGE2) in the human multiple myeloma (MM) cytokine network, involving interleukin 6 (IL-6) and interleukin 1 (IL-1) as ess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2832f526164375188f1ad945654a2b64
https://hal.archives-ouvertes.fr/hal-02192669

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Surgical repair versus medical treatment of varicocele in the rat: pharmacological manipulation of the varicocelized testicle

Autor: I. Nakamura, Ikuo Miyagawa, H Saeki, T. Okazaki, T. Shimamoto, Chihiro Takahashi, Nikolaos Sofikitis, H. Kadowaki

Publikováno v: European urology. 22(1)

Human chorionic gonadotropin, kallikrein, indomethacin, and hydralazine were administered to different groups of varicocelized rats, while surgical repair of the varicocele was performed in another group of rats. The effects of conservative and surgi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b88b18c8e767e8f69a3e91c2f94fb4
https://pubmed.ncbi.nlm.nih.gov/1425845

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Effect of indomethacin on binding of bilirubin to albumin

Autor: Chap-Yung Yeung, B C Lam, H N Wong

Publikováno v: Archives of Disease in Childhood. 65:690-691

The effect of indomethacin on the binding of bilirubin to protein was studied in vitro by the horseradish peroxidase oxidation method. Plasma indomethacin concentrations ranging from 1500 micrograms/l to 4500 micrograms/l, which were much higher than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c37c99f83c42c9dc49fa87cb729202
https://doi.org/10.1136/adc.65.7_spec_no.690

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インドメサシンのプロラクチン放出抑制効果

Autor: Ito, Haruo, Kawamura, Kenji, Kataumi, Zenzo, Sumiya, Hidenori, Takahara, Masanobu, Aikawa, Hideo, Shimazaki, Jun

Publikováno v: 泌尿器科紀要. 30(1):17-20

インドメサシン100 mgの直腸内投与で男子血中プロラクチン濃度は有意に低下した.血中LHレベルは軽度低下したが, 有意差はなかった.血中FSHは変化しなかった
Indomethacin administered intrarec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::c174e4be7eec0e67b1bcd0dcb2a958b6
http://hdl.handle.net/2433/118099

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