Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation

Autor: Robert Carlisle, Eloise Thomas, Katherine A. Vallis, Jyothi U. Menon, Rebecca L. Miller, Martin R. Gill, Michael D. Gray, Sheena Wallington, Joshua Owen, Irini Skaripa-Koukelli

Publikováno v: Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2020, 319, pp.222-233. ⟨10.1016/j.jconrel.2019.12.045⟩
Owen, J, Thomas, E, Menon, J, Gray, M, Skaripa-Koukelli, I, Gill, M R, Wallington, S, Miller, R L, Vallis, K & Carlisle, R 2020, ' Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation ', Journal of Controlled Release, vol. 319, pp. 222-233 . https://doi.org/10.1016/j.jconrel.2019.12.045

The purpose of this exploratory study was to investigate the combination of a radiopharmaceutical, nanoparticles and ultrasound (US) enhanced delivery to develop a clinically viable therapeutic strategy for tumours overexpressing the epidermal growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85bd00a02777357f3568b657b214faa
https://hal.archives-ouvertes.fr/hal-02547889

Development of radioimmunoconjugates as theranostic agents based on the anti-HER2 monoclonal antibody (trastuzumab): influence of chelating agents and radionuclides on biological properties

Autor: MIRANDA, ANA C.C.

Publikováno v: Repositório Institucional do IPEN
Instituto de Pesquisas Energéticas e Nucleares (IPEN)
instacron:IPEN

Submitted by Pedro Silva Filho (pfsilva@ipen.br) on 2021-09-10T19:02:04Z No. of bitstreams: 0 Made available in DSpace on 2021-09-10T19:02:04Z (GMT). No. of bitstreams: 0 O c??ncer de mama ?? a segunda maior causa de mortalidade no mundo. Os tumores

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::d642ea127259fe667fcc84378eb725f7
http://repositorio.ipen.br/handle/123456789/32247

Estudo das impurezas radioativas gama emissoras presentes nos radiofármacos produzidos no IPEN-CNEN/SP

Autor: ALMEIDA, JAMILLE da S.

Publikováno v: Repositório Institucional do IPENInstituto de Pesquisas Energéticas e NuclearesIPEN.

Submitted by Pedro Silva Filho (pfsilva@ipen.br) on 2017-11-22T17:07:51Z No. of bitstreams: 0
Made available in DSpace on 2017-11-22T17:07:51Z (GMT). No. of bitstreams: 0
Este trabalho tem como objetivo investigar a concentração de impure

Externí odkaz: http://repositorio.ipen.br:8080/xmlui/handle/123456789/28039

Feasibility of SPECT-CT imaging to study the pharmacokinetics of antisense oligonucleotides in a mouse model of Duchenne muscular dystrophy

Antisense oligonucleotides (AONs) are promising candidates for treatment of Duchenne muscular dystrophy (DMD), a severe and progressive disease resulting in premature death. However, more knowledge on the pharmacokinetics of new AON drug candidates i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::92333a1e48c0d74d325fa64eeb475a3f
http://resolver.tudelft.nl/uuid:69f24d6e-b03d-4e05-ac81-8dac4d8771e3

Study of labelling of bombesin derivatives with 111-indium and 68-galium and evaluation of biological properties for application in SPECT and PET

Autor: Ricardo De Souza Oliveira

Publikováno v: Repositório Institucional do IPEN
Instituto de Pesquisas Energéticas e Nucleares (IPEN)
instacron:IPEN
Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

Receptores para o peptídeo liberador de gastrina (GRPr) são super expressos em vários tipos de células cancerígenas, incluindo câncer de mama e próstata. A Bombesina é um análogo do peptídeo GRP de mamíferos que se liga com alta especifici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d53cc529cc8395d832d5f3e12640a7
https://doi.org/10.11606/d.85.2014.tde-08122015-085946