Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Indira, Pokkunuri"'
Publikováno v:
Clinical and Experimental Hypertension, Vol 42, Iss 6, Pp 571-579 (2020)
Purpose Vehicle exhaust emissions primarily comprise of nitrogen, oxygen, water, CO2, NO2, CO, hydrocarbons and particulate matter. While adverse effects of hydrocarbon and particulate matter on cardiovascular functions are known, the effect of pro-o
Externí odkaz:
https://doaj.org/article/5264091de59c49eab45cacbfc4167d4e
Publikováno v:
FEBS Open Bio, Vol 6, Iss 12, Pp 1273-1284 (2016)
The redox‐sensitive Sp family transcription factor has been linked to the regulation of angiotensin II type 1 receptor (AT1R). However, the exact mechanism of AT1R regulation in renal cells is poorly understood. We tested the specificity of reactiv
Externí odkaz:
https://doaj.org/article/1668319267f44242b3f31fdc52c7dbbc
Publikováno v:
Am J Physiol Renal Physiol
Renal proximal tubular apoptosis plays a critical role in kidney health and disease. However, cellular molecules that trigger renal apoptosis remain elusive. Here, we evaluated the effect of inhibiting protein disulfide isomerase (PDI), a critical th
Publikováno v:
Reproductive Sciences. 28:37-42
There is a growing evidence for the public health hazards associated with waterpipe tobacco smoking (WTS). While the adverse effects of WTS exposure during pregnancy on the offspring are widely reported, its impact during breastfeeding remains less u
Publikováno v:
Clinical and Experimental Hypertension. 42:571-579
Vehicle exhaust emissions primarily comprise of nitrogen, oxygen, water, CO Here, using an animal model of a simulated mixture of pro-oxidants (0.04% CO The systolic and diastolic blood pressure, heart rate and glomerular filtration rate remained unc
Autor:
Nour Al-Sawalha, Indira Pokkunuri, Ozozoma Omoluabi, Hosu Kim, Vaidehi J Thanawala, Adrian Hernandez, Richard A Bond, Brian J Knoll
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132559 (2015)
Mucus hypersecretion by airway epithelium is a hallmark of inflammation in allergic asthma and results in airway narrowing and obstruction. Others have shown that administration a TH2 cytokine, IL-13 is sufficient to cause mucus hypersecretion in viv
Externí odkaz:
https://doaj.org/article/878dd13d12874a7e866e2d60b1e4fa78
Publikováno v:
FEBS Open Bio
The redox‐sensitive Sp family transcription factor has been linked to the regulation of angiotensin II type 1 receptor (AT1R). However, the exact mechanism of AT1R regulation in renal cells is poorly understood. We tested the specificity of reactiv
Publikováno v:
American journal of physiology. Renal physiology. 315(5)
We tested a hypothesis that superoxide, by inducing Sp3, increases renal renin activity, renal angiotensin II type 1 receptor (AT1R) function, and blood pressure (BP) in rats. Group 1 rats were treated with vehicle, saline. Group 2 rats were treated
Autor:
Long P, Nguyen, Nour A, Al-Sawalha, Sergio, Parra, Indira, Pokkunuri, Ozozoma, Omoluabi, Adedoyin A, Okulate, Elizabeth, Windham Li, Matthew, Hazen, Jose M, Gonzalez-Granado, Craig J, Daly, John C, McGrath, Michael J, Tuvim, Brian J, Knoll, Burton F, Dickey, Richard A, Bond
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(43)
Activation of β2-adrenoreceptors (β2ARs) on airway smooth muscle cells produces airway relaxation, and β2AR agonists are the most widely used bronchodilators for treating asthma. Paradoxically, murine models show β2AR activation is also required
Autor:
Jose M. Gonzalez-Granado, Ozozoma Omoluabi, Michael J. Tuvim, John C. McGrath, Craig J. Daly, Indira Pokkunuri, Adedoyin A. Okulate, Richard A. Bond, Burton F. Dickey, Sergio Parra, Brian J. Knoll, Elizabeth Windham Li, Long P. Nguyen, Matthew L. Hazen, Nour A. Al-Sawalha
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
The mostly widely used bronchodilators in asthma therapy are β2-adrenoreceptor (β2AR) agonists, but their chronic use causes paradoxical adverse effects. We have previously determined that β2AR activation is required for expression of the asthma p