Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Indika Kumarapperuma"'
Autor:
Zhong Ren, Cong Wang, Heewhan Shin, Sepalika Bandara, Indika Kumarapperuma, Michael Y. Ren, Weijia Kang, Xiaojing Yang
Publikováno v:
IUCrJ, Vol 7, Iss 6, Pp 1009-1018 (2020)
Direct observation of functional motions in protein structures is highly desirable for understanding how these nanomachineries of life operate at the molecular level. Because cryogenic temperatures are non-physiological and may prohibit or even alter
Externí odkaz:
https://doaj.org/article/0de576d0cd98438e85b08cac7068ee0e
Autor:
Jimena Rinaldi, Ignacio Fernández, Heewhan Shin, Gabriela Sycz, Semini Gunawardana, Indika Kumarapperuma, Juan M. Paz, Lisandro H. Otero, María L. Cerutti, Ángeles Zorreguieta, Zhong Ren, Sebastián Klinke, Xiaojing Yang, Fernando A. Goldbaum
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Bacteria employ two-component systems (TCSs) to sense and respond to changes in their surroundings. At the core of the TCS signaling pathway is the multidomain sensor histidine kinase, where the enzymatic activity of its output domain is allosterical
Externí odkaz:
https://doaj.org/article/08a49c821c0046f7a784f88ec818881e
Publikováno v:
Photochemical & Photobiological Sciences.
Autor:
Sang Jin Lee, Tae Wu Kim, Jong Goo Kim, Cheolhee Yang, So Ri Yun, Changin Kim, Zhong Ren, Indika Kumarapperuma, Jane Kuk, Keith Moffat, Xiaojing Yang, Hyotcherl Ihee
Publikováno v:
Science Advances. 8
Bacteriophytochromes (BphPs) are photoreceptors that regulate a wide range of biological mechanisms via red light–absorbing (Pr)–to–far-red light–absorbing (Pfr) reversible photoconversion. The structural dynamics underlying Pfr-to-Pr photoco
Autor:
Zhong Ren, Xiaojing Yang, Indika Kumarapperuma, Irin P. Tom, Weijia Kang, Cong Wang, Linta M. Biju
Publikováno v:
Journal of visualized experiments : JoVE. (181)
Biochemical reactions and biological processes can be best understood by demonstrating how proteins transition among their functional states. Since cryogenic temperatures are non-physiological and may prevent, deter, or even alter protein structural
Autor:
Weijia Kang, Zhong Ren, Heewhan Shin, Cong Wang, Sepalika Bandara, Michael Y Ren, Xiaojing Yang, Indika Kumarapperuma
Publikováno v:
IUCrJ
IUCrJ, Vol 7, Iss 6, Pp 1009-1018 (2020)
IUCrJ, Vol 7, Iss 6, Pp 1009-1018 (2020)
An automated platform for diffraction experiments at room temperature for the study of macromolecular structures and dynamics with important biological significance is reported here. This platform preserves the virgin quality of crystal samples and r
Autor:
Xiaojing Yang, Linta Biju, Cong Wang, Weijia Kang, Irin Pottanani Tom, Indika Kumarapperuma Arachchige, Zhong Ren
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 78:a158-a158
Autor:
Xiaojing Yang, Angeles Zorreguieta, Juan M. Paz, Sebastián Klinke, Indika Kumarapperuma, Ignacio Fernandez, Jimena Rinaldi, Fernando Alberto Goldbaum, Lisandro H. Otero, Maria Laura Cerutti, Zhong Ren, Semini Gunawardana, Gabriela Sycz, Heewhan Shin
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
The ability to sense and respond to environmental cues is essential for adaptation and survival in living organisms. In bacteria, this process is accomplished by multidomain sensor histidine kinases that undergo autophosphorylation in response to spe
Autor:
Indika Kumarapperuma, Kes Lynn Joseph, Cong Wang, Linta M. Biju, Irin P. Tom, Kourtney D. Weaver, Théophile Grébert, Frédéric Partensky, Wendy M. Schluchter, Xiaojing Yang
Publikováno v:
Structure. 30:564-574.e3
Chromophore attachment of the light-harvesting apparatus represents one of the most important post-translational modifications in photosynthetic cyanobacteria. Extensive pigment diversity of cyanobacteria critically depends on bilin lyases that coval
Autor:
Zhong Ren, Kalinga Bowatte, Indika Kumarapperuma, Medine Ayhan, Sepalika Bandara, Heewhan Shin, Semini Gunawardana, Xiaoli Zeng, Xiaojing Yang, Cong Wang
Publikováno v:
Lab on a Chip. 18:2246-2256
Recent developments in serial crystallography at X-ray free electron lasers (XFELs) and synchrotrons have been driven by two scientific goals in structural biology – first, static structure determination from nano or microcrystals of membrane prote