Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Indigo V.L. Rose"'
Autor:
Emmy Li, Camila Benitez, Steven C. Boggess, Mark Koontz, Indigo V.L. Rose, Nina Draeger, Olivia M. Teter, Avi J. Samelson, Erik M. Ullian, Martin Kampmann
SummaryThe sheer complexity of the brain has complicated our ability to understand its cellular mechanisms in health and disease. Genome-wide association studies have uncovered genetic variants associated with specific neurological phenotypes and dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056f05365389b33cf38a55e21dff7f01
https://doi.org/10.1101/2023.04.26.538498
https://doi.org/10.1101/2023.04.26.538498
Autor:
Eva Hernando, Robert J. Schneider, Shane A. Liddelow, Kelly V. Ruggles, Beatrix Ueberheide, Ronald B. DeMattos, Paul Mathews, Yue-Ming Li, Iman Osman, Youssef Zaim Wadghiri, George Jour, Robert Rogers, Melissa Call, Eleazar C. Vega y Saenz de Miera, Jenny Chen, James A. Tranos, Nicole M. Eskow, Gillian Baptiste, Alfredo Floristán, Richard Von Itter, Diana Argibay, Alcida Karz, Francisco Galán-Echevarría, Eitan Wong, Avantika Dhabaria, Sorin A.A. Shadaloey, Lili M. Blumenberg, Indigo V.L. Rose, Grace Levinson, Kevin Kleffman
Supplementary Table from Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0097b470395ee65e94478abcfc7b1821
https://doi.org/10.1158/2159-8290.22541339
https://doi.org/10.1158/2159-8290.22541339
Autor:
Eva Hernando, Robert J. Schneider, Shane A. Liddelow, Kelly V. Ruggles, Beatrix Ueberheide, Ronald B. DeMattos, Paul Mathews, Yue-Ming Li, Iman Osman, Youssef Zaim Wadghiri, George Jour, Robert Rogers, Melissa Call, Eleazar C. Vega y Saenz de Miera, Jenny Chen, James A. Tranos, Nicole M. Eskow, Gillian Baptiste, Alfredo Floristán, Richard Von Itter, Diana Argibay, Alcida Karz, Francisco Galán-Echevarría, Eitan Wong, Avantika Dhabaria, Sorin A.A. Shadaloey, Lili M. Blumenberg, Indigo V.L. Rose, Grace Levinson, Kevin Kleffman
Supplementary Data from Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06285cdb7062b61c2bc82dc7ba7b2fe8
https://doi.org/10.1158/2159-8290.22541384.v1
https://doi.org/10.1158/2159-8290.22541384.v1
Autor:
Eva Hernando, Robert J. Schneider, Shane A. Liddelow, Kelly V. Ruggles, Beatrix Ueberheide, Ronald B. DeMattos, Paul Mathews, Yue-Ming Li, Iman Osman, Youssef Zaim Wadghiri, George Jour, Robert Rogers, Melissa Call, Eleazar C. Vega y Saenz de Miera, Jenny Chen, James A. Tranos, Nicole M. Eskow, Gillian Baptiste, Alfredo Floristán, Richard Von Itter, Diana Argibay, Alcida Karz, Francisco Galán-Echevarría, Eitan Wong, Avantika Dhabaria, Sorin A.A. Shadaloey, Lili M. Blumenberg, Indigo V.L. Rose, Grace Levinson, Kevin Kleffman
Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cccf7e3d8e14c4df1cb91f4fe232b6
https://doi.org/10.1158/2159-8290.c.6549617
https://doi.org/10.1158/2159-8290.c.6549617
Autor:
Eva Hernando, Robert J. Schneider, Shane A. Liddelow, Kelly V. Ruggles, Beatrix Ueberheide, Ronald B. DeMattos, Paul Mathews, Yue-Ming Li, Iman Osman, Youssef Zaim Wadghiri, George Jour, Robert Rogers, Melissa Call, Eleazar C. Vega y Saenz de Miera, Jenny Chen, James A. Tranos, Nicole M. Eskow, Gillian Baptiste, Alfredo Floristán, Richard Von Itter, Diana Argibay, Alcida Karz, Francisco Galán-Echevarría, Eitan Wong, Avantika Dhabaria, Sorin A.A. Shadaloey, Lili M. Blumenberg, Indigo V.L. Rose, Grace Levinson, Kevin Kleffman
Supplementary Figure from Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135dca2951942b810e536edab96562db
https://doi.org/10.1158/2159-8290.22541363
https://doi.org/10.1158/2159-8290.22541363
Autor:
Kevin Kleffman, Grace Levinson, Indigo V.L. Rose, Lili M. Blumenberg, Sorin A.A. Shadaloey, Avantika Dhabaria, Eitan Wong, Francisco Galán-Echevarría, Alcida Karz, Diana Argibay, Richard Von Itter, Alfredo Floristán, Gillian Baptiste, Nicole M. Eskow, James A. Tranos, Jenny Chen, Eleazar C. Vega y Saenz de Miera, Melissa Call, Robert Rogers, George Jour, Youssef Zaim Wadghiri, Iman Osman, Yue-Ming Li, Paul Mathews, Ronald B. DeMattos, Beatrix Ueberheide, Kelly V. Ruggles, Shane A. Liddelow, Robert J. Schneider, Eva Hernando
Publikováno v:
Cancer Discov
Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has t
Autor:
Shinji Sakamoto, Indigo V.L. Rose, Atsushi Kamiya, Dania Mallah, Ken Matoba, Eisuke Dohi, Xiaolei Zhu, Destynie J. Medeiros, Shin Ichi Kano, Takashi Imai
Publikováno v:
FEBS Open Bio, Vol 11, Iss 10, Pp 2678-2692 (2021)
FEBS Open Bio
FEBS Open Bio
Chronic stress induces peripheral and intracerebral immune changes and inflammation, contributing to neuropathology and behavioral abnormalities relevant to psychiatric disorders such as depression. Although the pathological implication of many perip
Publikováno v:
Nature Neuroscience. 24:1475-1487
Astrocytes undergo an inflammatory transition after infections, acute injuries and chronic neurodegenerative diseases. How this transition is affected by time and sex, its heterogeneity at the single-cell level and how sub-states are spatially distri
Autor:
Caroline B. Pantazis, Andrian Yang, Erika Lara, Justin A. McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kanaujiya, Jizhong Zou, David Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, Constance Medura, Christopher Tompkins, Stephen Hughes, Marianita Santiana, Faraz Faghri, Mike A. Nalls, Daniel Vitale, Shannon Ballard, Yue A. Qi, Daniel M. Ramos, Kailyn M. Anderson, Julia Stadler, Priyanka Narayan, Jason Papademetriou, Luke Reilly, Matthew P. Nelson, Sanya Aggarwal, Leah U. Rosen, Peter Kirwan, Venkat Pisupati, Steven L. Coon, Sonja W. Scholz, Theresa Priebe, Miriam Öttl, Jian Dong, Marieke Meijer, Lara J.M. Janssen, Vanessa S. Lourenco, Rik van der Kant, Dennis Crusius, Dominik Paquet, Ana-Caroline Raulin, Guojun Bu, Aaron Held, Brian J. Wainger, Rebecca M.C. Gabriele, Jackie M. Casey, Selina Wray, Dad Abu-Bonsrah, Clare L. Parish, Melinda S. Beccari, Don W. Cleveland, Emmy Li, Indigo V.L. Rose, Martin Kampmann, Carles Calatayud Aristoy, Patrik Verstreken, Laurin Heinrich, Max Y. Chen, Birgitt Schüle, Dan Dou, Erika L.F. Holzbaur, Maria Clara Zanellati, Richa Basundra, Mohanish Deshmukh, Sarah Cohen, Richa Khanna, Malavika Raman, Zachary S. Nevin, Madeline Matia, Jonas Van Lent, Vincent Timmerman, Bruce R. Conklin, Katherine Johnson Chase, Ke Zhang, Salome Funes, Daryl A. Bosco, Lena Erlebach, Marc Welzer, Deborah Kronenberg-Versteeg, Guochang Lyu, Ernest Arenas, Elena Coccia, Lily Sarrafha, Tim Ahfeldt, John C. Marioni, William C. Skarnes, Mark R. Cookson, Michael E. Ward, Florian T. Merkle
Publikováno v:
Cell stem cell 29(12), 1685-1702.e22 (2022). doi:10.1016/j.stem.2022.11.004
Cell stem cell
Cell Stem Cell, 29(12), 1685-1702.e22. Cell Press
Pantazis, C B, Yang, A, Lara, E, McDonough, J A, Blauwendraat, C, Peng, L, Oguro, H, Kanaujiya, J, Zou, J, Sebesta, D, Pratt, G, Cross, E, Blockwick, J, Buxton, P, Kinner-Bibeau, L, Medura, C, Tompkins, C, Hughes, S, Santiana, M, Faghri, F, Nalls, M A, Vitale, D, Ballard, S, Qi, Y A, Ramos, D M, Anderson, K M, Stadler, J, Narayan, P, Papademetriou, J, Reilly, L, Nelson, M P, Aggarwal, S, Rosen, L U, Kirwan, P, Pisupati, V, Coon, S L, Scholz, S W, Priebe, T, Öttl, M, Dong, J, Meijer, M, Janssen, L J M, Lourenco, V S, van der Kant, R, Crusius, D, Paquet, D, Raulin, A C, Bu, G, Held, A, Wainger, B J, Gabriele, R M C, Casey, J M, Wray, S, Abu-Bonsrah, D, Parish, C L, Beccari, M S, Cleveland, D W, Li, E, Rose, I V L, Kampmann, M, Calatayud Aristoy, C, Verstreken, P, Heinrich, L, Chen, M Y, Schüle, B, Dou, D, Holzbaur, E L F, Zanellati, M C, Basundra, R, Deshmukh, M, Cohen, S, Khanna, R, Raman, M, Nevin, Z S, Matia, M, Van Lent, J, Timmerman, V, Conklin, B R, Johnson Chase, K, Zhang, K, Funes, S, Bosco, D A, Erlebach, L, Welzer, M, Kronenberg-Versteeg, D, Lyu, G, Arenas, E, Coccia, E, Sarrafha, L, Ahfeldt, T, Marioni, J C, Skarnes, W C, Cookson, M R, Ward, M E & Merkle, F T 2022, ' A reference human induced pluripotent stem cell line for large-scale collaborative studies ', Cell Stem Cell, vol. 29, no. 12, pp. 1685-1702.e22 . https://doi.org/10.1016/j.stem.2022.11.004
Pantazis, C B, Yang, A, Lara, E, McDonough, J A, Blauwendraat, C, Peng, L, Oguro, H, Kanaujiya, J, Zou, J, Sebesta, D, Pratt, G, Cross, E, Blockwick, J, Buxton, P, Kinner-Bibeau, L, Medura, C, Tompkins, C, Hughes, S, Santiana, M, Faghri, F, Nalls, M A, Vitale, D, Ballard, S, Qi, Y A, Ramos, D M, Anderson, K M, Stadler, J, Narayan, P, Papademetriou, J, Reilly, L, Nelson, M P, Aggarwal, S, Rosen, L U, Kirwan, P, Pisupati, V, Coon, S L, Scholz, S W, Priebe, T, Öttl, M, Dong, J, Meijer, M, Janssen, L J M, Lourenco, V S, van der Kant, R, Crusius, D, Paquet, D, Raulin, A-C, Bu, G, Held, A, Wainger, B J, Gabriele, R M C, Casey, J M, Wray, S, Abu-Bonsrah, D, Parish, C L, Beccari, M S, Cleveland, D W, Li, E, Rose, I V L, Kampmann, M, Calatayud Aristoy, C, Verstreken, P, Heinrich, L, Chen, M Y, Schüle, B, Dou, D, Holzbaur, E L F, Zanellati, M C, Basundra, R, Deshmukh, M, Cohen, S, Khanna, R, Raman, M, Nevin, Z S, Matia, M, van Lent, J, Timmerman, V, Conklin, B R, Johnson Chase, K, Zhang, K, Funes, S, Bosco, D A, Erlebach, L, Welzer, M, Kronenberg-Versteeg, D, Lyu, G, Arenas, E, Coccia, E, Sarrafha, L, Ahfeldt, T, Marioni, J C, Skarnes, W C, Cookson, M R, Ward, M E & Merkle, F T 2022, ' A reference human induced pluripotent stem cell line for large-scale collaborative studies ', Cell Stem Cell, vol. 29, no. 12, pp. 1685-1702.e22 . https://doi.org/10.1016/j.stem.2022.11.004
Cell Stem Cell, 29(12), 1685-1702.e22. Elsevier
Cell stem cell
Cell Stem Cell, 29(12), 1685-1702.e22. Cell Press
Pantazis, C B, Yang, A, Lara, E, McDonough, J A, Blauwendraat, C, Peng, L, Oguro, H, Kanaujiya, J, Zou, J, Sebesta, D, Pratt, G, Cross, E, Blockwick, J, Buxton, P, Kinner-Bibeau, L, Medura, C, Tompkins, C, Hughes, S, Santiana, M, Faghri, F, Nalls, M A, Vitale, D, Ballard, S, Qi, Y A, Ramos, D M, Anderson, K M, Stadler, J, Narayan, P, Papademetriou, J, Reilly, L, Nelson, M P, Aggarwal, S, Rosen, L U, Kirwan, P, Pisupati, V, Coon, S L, Scholz, S W, Priebe, T, Öttl, M, Dong, J, Meijer, M, Janssen, L J M, Lourenco, V S, van der Kant, R, Crusius, D, Paquet, D, Raulin, A C, Bu, G, Held, A, Wainger, B J, Gabriele, R M C, Casey, J M, Wray, S, Abu-Bonsrah, D, Parish, C L, Beccari, M S, Cleveland, D W, Li, E, Rose, I V L, Kampmann, M, Calatayud Aristoy, C, Verstreken, P, Heinrich, L, Chen, M Y, Schüle, B, Dou, D, Holzbaur, E L F, Zanellati, M C, Basundra, R, Deshmukh, M, Cohen, S, Khanna, R, Raman, M, Nevin, Z S, Matia, M, Van Lent, J, Timmerman, V, Conklin, B R, Johnson Chase, K, Zhang, K, Funes, S, Bosco, D A, Erlebach, L, Welzer, M, Kronenberg-Versteeg, D, Lyu, G, Arenas, E, Coccia, E, Sarrafha, L, Ahfeldt, T, Marioni, J C, Skarnes, W C, Cookson, M R, Ward, M E & Merkle, F T 2022, ' A reference human induced pluripotent stem cell line for large-scale collaborative studies ', Cell Stem Cell, vol. 29, no. 12, pp. 1685-1702.e22 . https://doi.org/10.1016/j.stem.2022.11.004
Pantazis, C B, Yang, A, Lara, E, McDonough, J A, Blauwendraat, C, Peng, L, Oguro, H, Kanaujiya, J, Zou, J, Sebesta, D, Pratt, G, Cross, E, Blockwick, J, Buxton, P, Kinner-Bibeau, L, Medura, C, Tompkins, C, Hughes, S, Santiana, M, Faghri, F, Nalls, M A, Vitale, D, Ballard, S, Qi, Y A, Ramos, D M, Anderson, K M, Stadler, J, Narayan, P, Papademetriou, J, Reilly, L, Nelson, M P, Aggarwal, S, Rosen, L U, Kirwan, P, Pisupati, V, Coon, S L, Scholz, S W, Priebe, T, Öttl, M, Dong, J, Meijer, M, Janssen, L J M, Lourenco, V S, van der Kant, R, Crusius, D, Paquet, D, Raulin, A-C, Bu, G, Held, A, Wainger, B J, Gabriele, R M C, Casey, J M, Wray, S, Abu-Bonsrah, D, Parish, C L, Beccari, M S, Cleveland, D W, Li, E, Rose, I V L, Kampmann, M, Calatayud Aristoy, C, Verstreken, P, Heinrich, L, Chen, M Y, Schüle, B, Dou, D, Holzbaur, E L F, Zanellati, M C, Basundra, R, Deshmukh, M, Cohen, S, Khanna, R, Raman, M, Nevin, Z S, Matia, M, van Lent, J, Timmerman, V, Conklin, B R, Johnson Chase, K, Zhang, K, Funes, S, Bosco, D A, Erlebach, L, Welzer, M, Kronenberg-Versteeg, D, Lyu, G, Arenas, E, Coccia, E, Sarrafha, L, Ahfeldt, T, Marioni, J C, Skarnes, W C, Cookson, M R, Ward, M E & Merkle, F T 2022, ' A reference human induced pluripotent stem cell line for large-scale collaborative studies ', Cell Stem Cell, vol. 29, no. 12, pp. 1685-1702.e22 . https://doi.org/10.1016/j.stem.2022.11.004
Cell Stem Cell, 29(12), 1685-1702.e22. Elsevier
Human induced pluripotent stem cell (iPSC) lines are a powerful tool for studying development and disease, but the considerable phenotypic variation between lines makes it challenging to replicate key findings and integrate data across research group
Autor:
Manuel D. Leonetti, Saeed Fathi, Aimee W. Kao, Kari A. Herrington, Sophie Bax, Martin Kampmann, Kun Leng, Marcus Y. Chin, Joshua E. Elias, Frank McCarthy, Indigo V.L. Rose, Brendan Rooney
Inflammatory reactive astrocytes lose homeostatic functions and can be neurotoxic, potentially contributing to neurodegenerative diseases. However, the underlying cell biological mechanisms are not fully understood. Here, we demonstrate that lysosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf62582038ac0c543128bc3b8140882f
https://doi.org/10.1101/2021.09.11.459904
https://doi.org/10.1101/2021.09.11.459904