Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Indigo V. L. Rose"'
Autor:
Kun Leng, Brendan Rooney, Frank McCarthy, Wenlong Xia, Indigo V. L. Rose, Sophie Bax, Marcus Chin, Saeed Fathi, Kari A. Herrington, Manuel Leonetti, Aimee Kao, Stephen P. J. Fancy, Joshua E. Elias, Martin Kampmann
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Astrocytes respond and contribute to neuroinflammation by adopting inflammatory reactive states. Although recent efforts have characterized the gene expression signatures associated with these reactive states, the cell biology underlying inf
Externí odkaz:
https://doaj.org/article/3362c7cd0c774b99bc1e41cc97a52ae6
Autor:
Hyosung Kim, Kun Leng, Jinhee Park, Alexander G. Sorets, Suil Kim, Alena Shostak, Rebecca J. Embalabala, Kate Mlouk, Ketaki A. Katdare, Indigo V. L. Rose, Sarah M. Sturgeon, Emma H. Neal, Yan Ao, Shinong Wang, Michael V. Sofroniew, Jonathan M. Brunger, Douglas G. McMahon, Matthew S. Schrag, Martin Kampmann, Ethan S. Lippmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Inflammation of brain endothelial cells is seen in neurodegenerative conditions and in aging. Here the authors examine the role of astrocytes in blood brain barrier function using an iPSC-derived cell co-culture model.
Externí odkaz:
https://doaj.org/article/106dfd6155e1471aa3dfbd079fe49bd4
Autor:
Shinji Sakamoto, Dania Mallah, Destynie J. Medeiros, Eisuke Dohi, Takashi Imai, Indigo V. L. Rose, Ken Matoba, Xiaolei Zhu, Atsushi Kamiya, Shin‐ichi Kano
Publikováno v:
FEBS Open Bio, Vol 11, Iss 10, Pp 2678-2692 (2021)
Chronic stress induces peripheral and intracerebral immune changes and inflammation, contributing to neuropathology and behavioral abnormalities relevant to psychiatric disorders such as depression. Although the pathological implication of many perip
Externí odkaz:
https://doaj.org/article/57d0c3ba350a45e489ef8bf70fc383d8
Autor:
Kristin Hartmann, Diego Sepulveda-Falla, Indigo V. L. Rose, Charlotte Madore, Christiane Muth, Jakob Matschke, Oleg Butovsky, Shane Liddelow, Markus Glatzel, Susanne Krasemann
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Astrogliosis and activation of microglia are hallmarks of prion diseases in humans and animals. Both were viewed to be rather independent events in disease pathophysiology, with proinflammatory microglia considered to be the potential neurot
Externí odkaz:
https://doaj.org/article/a08887f6a7ab410092e18ec3fc60b63a
Autor:
Kun Leng, Indigo V. L. Rose, Hyosung Kim, Wenlong Xia, Wilber Romero-Fernandez, Brendan Rooney, Mark Koontz, Emmy Li, Yan Ao, Shinong Wang, Mitchell Krawczyk, Julia TCW, Alison Goate, Ye Zhang, Erik M. Ullian, Michael V. Sofroniew, Stephen P. J. Fancy, Matthew S. Schrag, Ethan S. Lippmann, Martin Kampmann
Publikováno v:
Nature neuroscience, vol 25, iss 11
Nat Neurosci
Nat Neurosci
Astrocytes become reactive in response to insults to the central nervous system by adopting context-specific cellular signatures and outputs, but a systematic understanding of the underlying molecular mechanisms is lacking. In this study, we develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b04940260c4e04207c7276cc0710dfb
https://escholarship.org/uc/item/91n3m43s
https://escholarship.org/uc/item/91n3m43s
Autor:
Haley E. Titus, Huan Xu, Andrew P. Robinson, Priyam A. Patel, Yanan Chen, Damiano Fantini, Valerie Eaton, Molly Karl, Eric D. Garrison, Indigo V. L. Rose, Ming Yi Chiang, Joseph R. Podojil, Roumen Balabanov, Shane A. Liddelow, Robert H. Miller, Brian Popko, Stephen D. Miller
Publikováno v:
Glia. 70(10)
Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease characterized by inflammation, demyelination, and neurodegeneration. The ideal MS therapy would both specifically inhibit the underlying autoimmune response and promote repa
Publikováno v:
Nature neuroscience. 24(10)
Astrocytes undergo an inflammatory transition after infections, acute injuries and chronic neurodegenerative diseases. How this transition is affected by time and sex, its heterogeneity at the single-cell level and how sub-states are spatially distri
Autor:
Kristin, Hartmann, Diego, Sepulveda-Falla, Indigo V L, Rose, Charlotte, Madore, Christiane, Muth, Jakob, Matschke, Oleg, Butovsky, Shane, Liddelow, Markus, Glatzel, Susanne, Krasemann
Publikováno v:
Acta Neuropathologica Communications
Astrogliosis and activation of microglia are hallmarks of prion diseases in humans and animals. Both were viewed to be rather independent events in disease pathophysiology, with proinflammatory microglia considered to be the potential neurotoxic spec