Výsledky vyhledávání - "Inderjit S. Mercy"

Transgene silencing may be mediated by aberrant sense promoter sequence transcripts generated from cryptic promoters

Autor: Reidunn B. Aalen, Morten C. Eike, Inderjit S. Mercy

Publikováno v: Cellular and Molecular Life Sciences CMLS. 62:3080-3091

To investigate whether silencing of a T-DNA-carried nptII gene in five single-copy transgenic Arabidopsis lines might be due to position effects, genomic DNA flanking the insertions was analysed for gene density, GC content, presence of short repeats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b4af3e353e87f32bda9830790a072d
https://doi.org/10.1007/s00018-005-5301-2

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Analyses of single-copy Arabidopsis T-DNA-transformed lines show that the presence of vector backbone sequences, short inverted repeats and DNA methylation is not sufficient or necessary for the induction of transgene silencing

Autor: Inderjit S. Mercy, Dag Andre Nymoen, Camilla Haslekås, Anne Mari Håkelien, Reidunn B. Aalen, Anita Berg, Melinka A. Butenko, Biljana Stangeland, Leonardo A. Meza-Zepeda, Trine J. Meza, Magne Skårn

Publikováno v: Nucleic Acids Research. 30:4556-4566

In genetically transformed plants, transgene silencing has been correlated with multiple and complex insertions of foreign DNA, e.g. T-DNA and vector backbone sequences. Occasionally, single-copy transgenes also suffer transgene silencing. We have co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132825b92f0c9b4545fad97911a28287
https://doi.org/10.1093/nar/gkf568

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The Arabidopsis SET-domain protein ASHR3 is involved in stamen development and interacts with the bHLH transcription factor ABORTED MICROSPORES (AMS)

Autor: Vibeke Alm, Tage Thorstensen, Rein Aasland, Paul E. Grini, Inderjit S. Mercy, Sigrid Erdal, Reidunn B. Aalen

Publikováno v: Plant molecular biology. 66(1-2)

The Arabidopsis thaliana genome contains more than 30 genes encoding SET-domain proteins that are thought to be epigenetic regulators of gene expression and chromatin structure. SET-domain proteins can be divided into subgroups, and members of the Po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967a1e0211af7e26fa8d20352000a090
https://pubmed.ncbi.nlm.nih.gov/17978851

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An inverted repeat transgene with a structure that cannot generate double-stranded RNA, suffers silencing independent of DNA methylation

Autor: Kjetill S. Jakobsen, Trine J. Meza, Magne Skårn, Reidunn B. Aalen, Morten C. Eike, Inderjit S. Mercy

Publikováno v: Transgenic research. 15(4)

Transgene silencing in plants is most often dependent on homologous sequences, e.g. tandemly repeated T-DNAs. We have identified an Arabidopsis line (ex2–4 line 4) displaying silencing of the T-DNA-born nptII gene. This line contains a truncated co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59e3d6c9882578eace7a84e62b86037
https://pubmed.ncbi.nlm.nih.gov/16906449

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