Allopurinol treatment reduced vascular remodeling and improved vascular functions in monocrotaline-induced pulmonary hypertensive rats

Autor: Gokcen, Telli, Inci, Kazkayasi, Inci, Ergonul E., Sevgen, Onder, Serdar, Uma

Publikováno v: In Pulmonary Pharmacology & Therapeutics December 2022 77

Efeito de 5-hidroxitriptofano no edema de pata de camundongo induzido por carragenina

Autor: Gokçen TELLI, Inci KAZKAYASI, Serdar UMA

Publikováno v: Revista de Nutrição v.34 2021
Revista de Nutrição
Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron:PUC_CAMP
Revista de Nutrição, Volume: 34, Article number: e200119, Published: 02 JUN 2021
Revista de Nutrição, Vol 34 (2021)

Objective 5-Hydroxytryptophan is the precursor compound of serotonin biosynthesis. The oral absorption of 5-Hydroxytryptophan is close to 100% and, unlike serotonin, it crosses the blood-brain barrier freely. 5-Hydroxytryptophan has been used as a fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f71da31226abe57c1d19bbdaab3a19
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732021000100315

Insulin deprivation decreases insulin degrading enzyme levels in primary cultured cortical neurons and in the cerebral cortex of rats with streptozotocin-induced diabetes

Autor: Nihan Burul-Bozkurt, Inci Kazkayasi, Angel Cedazo-Minguez, Can Pekiner, Muhammad-Al-Mustafa Ismail, Serdar Uma, Paula Merino-Serrais

Publikováno v: Pharmacological Reports. 70:677-683

Background Many studies have indicated a relationship between diabetes and Alzheimer’s disease (AD). However, the molecular mechanism underlying this association has not been clarified. Among several factors, insulin degrading enzyme (IDE), which p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aea305d255ecb88b6f65bcc5e22f9fd
https://doi.org/10.1016/j.pharep.2018.01.008

Lack of insulin results in reduced seladin-1 expression in primary cultured neurons and in cerebral cortex of STZ-induced diabetic rats

Autor: Ingemar Björkhem, Angel Cedazo-Minguez, Can Pekiner, Nihan Burul-Bozkurt, Muhammad-Al-Mustafa Ismail, Inci Kazkayasi, Cristina Parrado-Fernandez, Serdar Uma

Publikováno v: Neuroscience Letters. 633:174-181

Several studies demonstrated that Diabetes mellitus (DM) enhances the risk for Alzheimer's disease (AD). Although hyperglycemia and perturbed function of insulin signaling have been proposed to contribute to AD pathogenesis, the molecular mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83836aa8eece009bc196e3447d2b9ac8
https://doi.org/10.1016/j.neulet.2016.09.018

Effects of Experimental Diabetes on C/EBP Proteins in Rat Hippocampus, Sciatic Nerve and Ganglia

Autor: Nihan Burul-Bozkurt, Inci Kazkayasi, Pelin Kelicen-Ugur, Can Pekiner, Sevgen Onder

Publikováno v: Cellular and Molecular Neurobiology. 33:559-567

Neurodegeneration is one of the most important complications of diabetes mellitus (DM). The exact mechanisms underlying neurodegeneration related to diabetic complications such as cognitive deficits and peripheral neuropathy are not clarified yet. Du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbc126ff239b7fff87d22cbe377bd6d
https://doi.org/10.1007/s10571-013-9924-9