Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Inbar Pilzer"'
Autor:
Tal Keren-Kaplan, Lee Zeev Peters, Olga Levin-Kravets, Ilan Attali, Oded Kleifeld, Noa Shohat, Shay Artzi, Ori Zucker, Inbar Pilzer, Noa Reis, Michael H. Glickman, Shay Ben-Aroya, Gali Prag
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Ubiquitin (Ub) receptors are responsible for the recognition of ubiquitylated proteins. Here the authors describe the crystal structure of the ubiquitylated form of the Ub-receptor Rpn10, which suggest that ubiquitylation of Rpn10 promotes its dissoc
Externí odkaz:
https://doaj.org/article/8431d5b994ec4a4ca5d12daa3a68d3a3
Autor:
Tamir Baram, Alexander Varvak, Shay Artzi, Gali Prag, Noa Shohat, Shay Ben-Aroya, Xiaojing Shi, Ilan Attali, Inbar Pilzer, Yael Reshef, Neta Tanner, Corine Katina, Ori Zucker, Anna Shusterman, Olga Levin-Kravets, Tal Keren-Kaplan
Publikováno v:
Nature Methods. 13:945-952
About one-third of the eukaryotic proteome undergoes ubiquitylation, but the enzymatic cascades leading to substrate modification are largely unknown. We present a genetic selection tool that utilizes Escherichia coli, which lack deubiquitylases, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fd310f9459c1e62a0c5dc7755f1f3f
https://doi.org/10.1038/nmeth.4003
https://doi.org/10.1038/nmeth.4003
Autor:
Reuven Wiener, Bayan Mashahreh, Kobi J. Simpson-Lavy, Dieter A. Wolf, Daniela Rotin, Tal Keren-Kaplan, Ilan Attali, Olga Levin-Kravets, Avinash Persaud, Martin Kupiec, Gali Prag, Khatereh Motamedchaboki, Inbar Pilzer, William Sam Tobelaim
Publikováno v:
The EMBO journal. 36(4)
Ubiquitylation controls protein function and degradation. Therefore, ubiquitin ligases need to be tightly controlled. We discovered an evolutionarily conserved allosteric restraint mechanism for Nedd4 ligases and demonstrated its function with divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ee329f0adccd2c450b46f604c7e989
https://pubmed.ncbi.nlm.nih.gov/28087580
https://pubmed.ncbi.nlm.nih.gov/28087580
Autor:
Lee Zeev Peters, Ori Zucker, Shay Ben-Aroya, Tal Keren-Kaplan, Olga Levin-Kravets, Oded Kleifeld, Gali Prag, Ilan Attali, Noa Shohat, Shay Artzi, Inbar Pilzer, Noa Reis, Michael H. Glickman
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
'Nature Communications ', vol: 7, pages: 12960-1-12960-12 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
'Nature Communications ', vol: 7, pages: 12960-1-12960-12 (2016)
Ubiquitin receptors decode ubiquitin signals into many cellular responses. Ubiquitin receptors also undergo coupled monoubiquitylation, and rapid deubiquitylation has hampered the characterization of the ubiquitylated state. Using bacteria that expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4671d6fb7739ab69c485fe75e42df5
https://pubmed.ncbi.nlm.nih.gov/27698474
https://pubmed.ncbi.nlm.nih.gov/27698474
Publikováno v:
EMBO reports. 16(3)
Reprogramming to pluripotency is a low-efficiency process at the population level. Despite notable advances to molecularly characterize key steps, several fundamental aspects remain poorly understood, including when the potential to reprogram is firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a55c0b0b9f8bcdebec4864b22d5cdb
https://pubmed.ncbi.nlm.nih.gov/25600117
https://pubmed.ncbi.nlm.nih.gov/25600117
Autor:
Mati Fridkin, Inna Divinsky, Avron D. Spier, Illana Gozes, Douglas E. Brenneman, Inbar Pilzer
Publikováno v:
Journal of Molecular Neuroscience. 20:315-322
Accelerated neuronal death brings about cognitive as well as motor and other dysfunctions. A major neuropeptide, vasoactive intestinal peptide (VIP), has been shown to be neuroprotective. However, VIP-based drug design is hampered by the instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622b45394a6c4dd749ff2f22578fbaf3
https://doi.org/10.1385/jmn:20:3:315
https://doi.org/10.1385/jmn:20:3:315
Publikováno v:
Neuropeptide Techniques ISBN: 9781588294685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01bdabf0914efc977cefa5f1681fafac
https://doi.org/10.1007/978-1-60327-099-1_4
https://doi.org/10.1007/978-1-60327-099-1_4
Publikováno v:
Neuropeptide Techniques ISBN: 9781588294685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dad51aa581bbabe182c74467eaabe79
https://doi.org/10.1007/978-1-60327-099-1_3
https://doi.org/10.1007/978-1-60327-099-1_3
Autor:
Illana Gozes, Inbar Pilzer
Publikováno v:
Annals of the New York Academy of Sciences. 1070
The pituitary adenylate cyclase-activating polypeptide (PACAP) receptor, PAC1, recognizes PACAP with a higher affinity than it recognizes vasoactive intestinal peptide (VIP) and belongs to the subfamily G protein–coupled receptors. So far, more tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b4b4ee2b4c171ff7a30ba7ff2d7a4f
https://pubmed.ncbi.nlm.nih.gov/16888214
https://pubmed.ncbi.nlm.nih.gov/16888214
Autor:
Illana Gozes, Inbar Pilzer
Publikováno v:
Peptides. 27(11)
Vasoactive intestinal peptide (VIP) was known to provide neuroprotection. Three VIP receptors have been cloned: VPAC1, VPAC2 and PAC1. A specific splice variant of PAC1 in the third cytoplasmatic loop, hop2, was implicated in VIP-related neuroprotect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09529185d699cde69f77c6bbffaa9c1f
https://pubmed.ncbi.nlm.nih.gov/16905223
https://pubmed.ncbi.nlm.nih.gov/16905223