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Akademický článek

Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study

Publikováno v: eLife, Vol 12 (2023)

Background: Viral infection is associated with a significant rewire of the host metabolic pathways, presenting attractive metabolic targets for intervention. Methods: We chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in

Externí odkaz: https://doaj.org/article/e2c42bb8edf74ef282600cb66a73a2be

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Akademický článek

Ombitasvir/paritaprevir/ritonavir & dasabuvir ± ribavirin following protease inhibitors failure - a prospective multi-centre trial

Autor: Liat Deutsch, Inbal Houri, Ziv Ben-Ari, Amir Shlomai, Ella Veitsman, Oranit Cohen-Ezra, Assaf Issachar, Orna Mor, Yael Gozlan, Rafael Bruck, Yoram Menachem, Shira Zelber-Sagi, Helena Katchman, Oren Shibolet

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)

Abstract Background Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and hepatocellular carcinoma. Treatment with first generation protease inhibitors (PI) + peg-interferon (pegIFN) and ribavirin (RBV) achieved sustained

Externí odkaz: https://doaj.org/article/8d8a09a64891489ca8134d6425a34e9c

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Humoral Response to the Third Dose of Sars-Cov-2 Vaccine in Kidney Transplant Recipients

Publikováno v: Transplantation Proceedings. 54:1439-1445

Most solid organ transplant recipients did not develop an appreciable serologic response after 2 doses of the mRNA SARS-CoV-2 vaccine.We analyzed the humoral response after a third dose of the BNT162b2 vaccine in 130 kidney transplant recipients, com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a68a5c0d30e599f8fefb424340d784e
https://doi.org/10.1016/j.transproceed.2022.02.011

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Barriers and Facilitators of Hepatitis C Care in Persons Coinfected with Human Immunodeficiency Virus

Autor: Nir Bar, Noa Bensoussan, Liane Rabinowich, Sharon Levi, Inbal Houri, Dana Ben-Ami Shor, Oren Shibolet, Orna Mor, Ella Weitzman, Dan Turner, Helena Katchman

Publikováno v: International Journal of Environmental Research and Public Health; Volume 19; Issue 22; Pages: 15237

Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are often co-transmitted. Viral coinfection results in worse outcomes. Persons who inject drugs (PWIDs) face barriers to medical treatment, but HCV treatment is indicated and effective ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e1ff415dfc511d4d55095da164f0d7

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Emergency department targeted screening for hepatitis C does not improve linkage to care

Autor: Yael Weksler, Inbal Houri, Liat Deutsch, Helena Katchman, Ofer Miller, Noya Horowitz, Oren Shibolet

Publikováno v: World Journal of Gastroenterology

Background Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease worldwide. New treatments for HCV revolutionized management and prompted the world health organization to set the goal of viral elimination by 2030. These develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908849e16132207418acf6ea180c9f10
http://europepmc.org/articles/PMC7459203

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Ombitasvir/paritaprevir/ritonavir & dasabuvir ± ribavirin following protease inhibitors failure - a prospective multi-centre trial

Autor: Helena Katchman, Assaf Issachar, Orna Mor, Oren Shibolet, Yoram Menachem, Ella Veitsman, Amir Shlomai, Liat Deutsch, Oranit Cohen-Ezra, Rafael Bruck, Yael Gozlan, Shira Zelber-Sagi, Ziv Ben-Ari, Inbal Houri

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Infectious Diseases

Background Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and hepatocellular carcinoma. Treatment with first generation protease inhibitors (PI) + peg-interferon (pegIFN) and ribavirin (RBV) achieved sustained virologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3c18f6058f1904385b254159f66a94
http://link.springer.com/article/10.1186/s12879-020-4921-3

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Kidney transplant recipients vaccinated before transplantation maintain superior humoral response to SARS‐CoV‐2 vaccine

Autor: Roni Baruch, Dan Turner, Moshe Shashar, Eugene Katchman, Idit F. Schwartz, Helena Katchman, Doron Schwartz, Inbal Houri, Merav Ben-Yehoyada, Liane Rabinowich, Yaacov Goykhman, Oren Shibolet, Tami Halperin, Ayelet Grupper, Sharon Levy

Publikováno v: Clinical Transplantation

Majority of transplant recipients did not develop an appreciable humoral response following SARS‐CoV‐2 vaccine, in contrast to dialysis patients and healthy individuals. We analyzed the serologic response to BNT162b2 (Pfizer‐BioNTech) vaccine i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce3a694cbe4eb5f95a409ae2b417d27
http://europepmc.org/articles/PMC8646320

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Repetitive amiodarone administration causes liver damage via adipose tissue ER stress-dependent lipolysis, leading to hepatotoxic free fatty acid accumulation

Autor: Ortal Shaffer, Inbal Houri, Sigal Fishman, Minna Holopainen, Reijo Käkelä, Oren Shibolet, Isabel Zvibel, E. Hubel

Drug-induced liver injury is an emerging form of acute and chronic liver disease that may manifest as fatty liver. Amiodarone (AMD), a widely used antiarrhythmic drug, can cause hepatic injury and steatosis by a variety of mechanisms, not all complet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc4a4083e65299cf0cc4fe29b0fc2cf
http://hdl.handle.net/10138/346177

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