Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Inaam A. Nakchbandi"'
Autor:
Franziska Wirth, Caren Zoeller, Alexander Lubosch, Jutta Schroeder-Braunstein, Guido Wabnitz, Inaam A. Nakchbandi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 58, Iss , Pp 101058- (2024)
Tumor cells can migrate from a primary cancer and form metastases by localizing to niches within other organs including the bone marrow, where tumor cells may exploit the hematopoietic stem cell niche. The precise composition of the premetastatic and
Externí odkaz:
https://doaj.org/article/7a41e04d0d844ecabbb935af4efe6cc8
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 837-850 (2021)
Understanding how the extracellular matrix affects cancer development constitutes an emerging research field. Fibronectin and collagen are two intriguing matrix components found in cancer. Large concentrations of fibronectin or collagen type I have b
Externí odkaz:
https://doaj.org/article/aa804aff65ba4e6cb95b3334d245a771
Publikováno v:
Cells, Vol 9, Iss 12, p 2717 (2020)
Fibronectin is a ubiquitous extracellular matrix protein that is produced by many cell types in the bone marrow and distributed throughout it. Cells of the stem cell niche produce the various isoforms of this protein. Fibronectin not only provides th
Externí odkaz:
https://doaj.org/article/8e7f4c2513c1417fb33fd8959bcbd3e5
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 385 (2020)
The regulation of the differentiation of the bone-forming cells, the osteoblasts, is complex. Many signaling pathways converge on the master regulator of osteoblast differentiation Runx2. The role of molecules that integrate several signaling pathway
Externí odkaz:
https://doaj.org/article/bbd3f49eae0248f090b9e9bb7fda6a55
Autor:
Inaam A. Nakchbandi, Karen Bieback, Markus Rojewski, Tilmann Todenhöfer, Jörg Hennenlotter, Arnulf Stenzl, Jan Dominik Kuhlmann, Theresa Link, Pauline Wimberger, Sarah Schott, Franz Jakob, Eva Altrock, Christopher Groth, Hiba Ghura, Stephanie Rossnagl
Supplementary-Figure 1 Tumor cell infiltration of other organs after PTH/ZA treatment (A) The combined treatment with PTH/ZA does not affect the homing of MDA tumor cells to other organs; n=14/15 in 2 experiments. Evaluation of blood vessel numbers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717d18fa9bb10fc37b754942043d53f8
https://doi.org/10.1158/0008-5472.22417320
https://doi.org/10.1158/0008-5472.22417320
Autor:
Inaam A. Nakchbandi, Karen Bieback, Markus Rojewski, Tilmann Todenhöfer, Jörg Hennenlotter, Arnulf Stenzl, Jan Dominik Kuhlmann, Theresa Link, Pauline Wimberger, Sarah Schott, Franz Jakob, Eva Altrock, Christopher Groth, Hiba Ghura, Stephanie Rossnagl
Supplementary-Table 1A. The markers for murine mesenchymal stromal cells were selected based on literature. Supplementary-Table 1B. Model summary of stepwise multiple-regression analysis of the relation of the selected murine MSC markers and homing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7675382532216bbef48eb4a5fef9c5ba
https://doi.org/10.1158/0008-5472.22417299
https://doi.org/10.1158/0008-5472.22417299
Autor:
Inaam A. Nakchbandi, Karen Bieback, Markus Rojewski, Tilmann Todenhöfer, Jörg Hennenlotter, Arnulf Stenzl, Jan Dominik Kuhlmann, Theresa Link, Pauline Wimberger, Sarah Schott, Franz Jakob, Eva Altrock, Christopher Groth, Hiba Ghura, Stephanie Rossnagl
Breast and prostate cancer cells home to the bone marrow, where they presumably hijack the hematopoietic stem cell niche. We characterize here the elusive premetastatic niche by examining the role of mesenchymal stromal cells (MSC) in cancer cell hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00431ff5f6367fe90e0a168756fa1a19
https://doi.org/10.1158/0008-5472.c.6509811
https://doi.org/10.1158/0008-5472.c.6509811
Autor:
Inaam A. Nakchbandi, Karen Bieback, Markus Rojewski, Tilmann Todenhöfer, Jörg Hennenlotter, Arnulf Stenzl, Jan Dominik Kuhlmann, Theresa Link, Pauline Wimberger, Sarah Schott, Franz Jakob, Eva Altrock, Christopher Groth, Hiba Ghura, Stephanie Rossnagl
Supplementary-Figure 1. Tumor cell infiltration of other organs after PTH/ZA treatment. Evaluation of blood vessel numbers and binding of cancer cells to vascular cells after PTH/ZA treatment. PTH/ZA treatment does not affect colony forming units of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f397a6ba9b8587c23966339ab627e16
https://doi.org/10.1158/0008-5472.22417302.v1
https://doi.org/10.1158/0008-5472.22417302.v1
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 837-850 (2021)
Neoplasia
Neoplasia (New York, N.Y.)
Neoplasia
Neoplasia (New York, N.Y.)
Highlights • Deletion of fibronectin in cancer cells prolongs survival • Pharmacologic inhibition of fibronectin deposition slows down cancer progression in two models • Decreasing fibronectin in the matrix diminishes proliferation in tumors an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e268ac146863ea724609643109711f0d
https://doi.org/10.1016/j.neo.2021.06.012
https://doi.org/10.1016/j.neo.2021.06.012
Autor:
Anja von Au, Matthaeus Vasel, Sabrina Kraft, Carla Sens, Norman Hackl, Alexander Marx, Philipp Stroebel, Jörg Hennenlotter, Tilman Todenhöfer, Arnulf Stenzl, Sarah Schott, Hans-Peter Sinn, Antoinette Wetterwald, Justo Lorenzo Bermejo, Marco G Cecchini, Inaam A Nakchbandi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 8, Pp 925-938 (2013)
Fibronectin is ubiquitously expressed in the extracellular matrix, and experimental evidence has shown that it modulates blood vessel formation. The relative contribution of local and circulating fibronectin to blood vessel formation in vivo remains
Externí odkaz:
https://doaj.org/article/1bd397fdc23c48fda9dccebf2d503938