Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ina V. Martin"'
Autor:
Xiyang Liu, Lucy Kathleen Reiss, Katharina C Reimer, Jürgen Floege, Thomas Rauen, Christina Alidousty, Daniela Hermert, Tammo Ostendorf, Ralf Weiskirchen, Daniel M. Breitkopf, Ina V. Martin, Ute Raffetseder
Publikováno v:
Kidney International. 97:741-752
Acute kidney injury is a common complication of advanced liver disease and increased mortality of these patients. Here, we analyzed the role of Y-box protein-1 (YB-1), a nucleic acid binding protein, in the bile duct ligation model of liver fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1378762abe9f88e3ad0e2f3f1845dea
https://doi.org/10.1016/j.kint.2019.10.024
https://doi.org/10.1016/j.kint.2019.10.024
Autor:
Ketan Patel, Tobias B. Huber, Felix Eichinger, Victor G. Puelles, Matthias Kretzler, Ina V. Martin, Elion Hoxha, Shun Lu, Andrea Paolini, Pierre-Louis Tharaux, Shuya Liu, Marco Sandri, Viji Nair, Antonios Matsakas, Olli Ritvos, Julian Schulze zur Wiesch, Caterina Tezze, Peter Boor, Rajasree Menon, Nicola Wanner, Maja T. Lindenmeyer, Temel Kilic, Dominik Kylies, Jan Eric Turner, Barbara M. Klinkhammer, Robert Mitchell, Clemens D. Cohen, Charlotte Meyer, Arja Pasternack, Oliver Kretz, Francesca Solagna, Yu Zhao, Guochao Wu, Saleh Omairi, Tammo Ostendorf
Publikováno v:
The Journal of Clinical Investigation
cited By 1 Skeletal muscle wasting is commonly associated with chronic kidney disease (CKD), resulting in increased morbidity and mortality. However, the link between kidney and muscle function remains poorly understood. Here, we took a complementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aee6b21de59ad8398746dac8ad04be
https://doi.org/10.1172/jci135821
https://doi.org/10.1172/jci135821
Autor:
Frank Lammert, Peter Boor, Erdenechimeg Shagdarsuren, Ina V. Martin, A Bohner, Susanne N. Weber, Jürgen Floege, Tammo Ostendorf, Ute Raffetseder
Publikováno v:
American Journal of Physiology-Renal Physiology. 314:F35-F46
Complement factor C5a has two known receptors, C5aR, which mediates proinflammatory effects, and C5L2, a potential C5a decoy receptor. We previously identified C5a/C5aR signaling as a potent profibrotic pathway in the kidney. Here we tested for the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5890a6abf814104bcb7f77cb01b6f139
https://doi.org/10.1152/ajprenal.00060.2017
https://doi.org/10.1152/ajprenal.00060.2017
Autor:
Daniel M. Breitkopf, Klaus Tenbrock, Jürgen Floege, Juliane Hermann, Vera Jankowski, Xiyang Liu, Ute Raffetseder, Ina V. Martin, Elisabeth F. Gröne, Fabian Groll, Jialin Wang, Daniela Hermert, Kim Ohl, Thomas Rauen, Tammo Ostendorf
Publikováno v:
Kidney international. 97(2)
Systemic lupus erythematosus (SLE) is an autoimmune disease and lupus nephritis is a major risk factor for morbidity and mortality. Notch-3 signaling induced by membrane-bound or soluble ligands such as YB-1 constitutes an evolutionarily conserved pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d727fcf2fbe022572c88ff64c6a5bcc7
https://pubmed.ncbi.nlm.nih.gov/31980071
https://pubmed.ncbi.nlm.nih.gov/31980071
Autor:
Juergen Floege, E. Groene, Ina V. Martin, Thomas Rauen, Ute Raffetseder, Daniel M. Breitkopf, Daniela Hermert, Tammo Ostendorf
Publikováno v:
SLE, Sjögren’s and APS – etiology, pathogenesis and animal models.
Background Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that affects the kidneys in about 50% of patients. Lupus nephritis (LN) is a major risk factor for overall morbidity and mortality in SLE patients. Notch signaling consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0028f1d0b9bc0b23b1207af9657c1673
https://doi.org/10.1136/annrheumdis-2018-eular.4628
https://doi.org/10.1136/annrheumdis-2018-eular.4628
Autor:
Stephanie Otten, Christoph Kuppe, Eva Miriam Buhl, Elisa A. Liehn, Claudia R.C. van Roeyen, Katharina Schuett, Tammo Ostendorf, Oliver Gross, Frank Eitner, Gerald S. Braun, Jürgen Floege, Peter Boor, Daniela Hermert, Ralf Weiskirchen, Ina V. Martin, Ulf Eriksson, Ute Raffetseder, Ana Drescher
Publikováno v:
Kidney international. 95(5)
Platelet-derived growth factors (PDGF) have been implicated in kidney disease progression. We previously found that PDGF-C is upregulated at sites of renal fibrosis and that antagonism of PDGF-C reduces fibrosis in the unilateral ureteral obstruction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e95be806a89591697effdb49ae3870
https://pubmed.ncbi.nlm.nih.gov/30827511
https://pubmed.ncbi.nlm.nih.gov/30827511
Autor:
Claudia R.C. van Roeyen, Josef Ehling, Janka Bábíčková, Petra A. I. Hautvast, Floor M.E.G. Steegh, Frank Eitner, Taizo Nakagawa, Peter Boor, Sonja Djudjaj, Ina V. Martin, Ulf Eriksson, Felix Gremse, Carine J. Peutz-Kootstra, Jürgen Floege, Tammo Ostendorf, Eva Bücher, Twan Lammers
Publikováno v:
American Journal of Pathology, 185(8), 2132-2142. Elsevier Science
American journal of pathology, 185(8), 2132-2142. Elsevier
American journal of pathology, 185(8), 2132-2142. Elsevier
We have identified platelet-derived growth factor (PDGF)-CC as a potent profibrotic mediator in kidney fibrosis and pro-angiogenic mediator in glomeruli. Because renal fibrosis is associated with progressive capillary rarefaction, we asked whether PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9783fbd01fab525f70ddea5b6c8e0d6
https://doi.org/10.1016/j.ajpath.2015.04.022
https://doi.org/10.1016/j.ajpath.2015.04.022
Autor:
Peter Boor, Michael Perkuhn, Ina V. Martin, Martin Weibrecht, Jürgen Gieseke, Christiane K. Kuhl, Felix Schoth, Jürgen Floege, Tammo Ostendorf, Stephanie Zok
Publikováno v:
Journal of Magnetic Resonance Imaging. 42:990-998
Purpose To assess the apparent diffusion coefficient (ADC) derived from diffusion-weighted (DW) magnetic resonance imaging (MRI) as a specific marker of renal fibrosis in rats with unilateral ureteral obstruction (UUO). Materials and Methods Thirteen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aed3f48b866e32e036bf03be8b7e600
https://doi.org/10.1002/jmri.24853
https://doi.org/10.1002/jmri.24853
Autor:
Sonja Djudjaj, Ina V. Martin, Eva Miriam Buhl, Jürgen Bernhagen, Nina J. Nothofer, Richard Bucala, Peter Boor, Marta Piecychna, Lin Leng, Jürgen Floege
Renal fibrosis is a common underlying process of progressive kidney diseases. We investigated the role of macrophage migration inhibitory factor (MIF), a pleiotropic proinflammatory cytokine, in this process. In mice subjected to unilateral ureteral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8586c8cfa2c6bc404e1b1d2c6213f996
https://europepmc.org/articles/PMC5698074/
https://europepmc.org/articles/PMC5698074/
Autor:
Bernard Perbal, Claudia R.C. van Roeyen, Ralf Weiskirchen, Jürgen Floege, Song Rong, Tammo Ostendorf, Stefan Fleckenstein, Ana Kaitovic, Christian Trautwein, Ina V. Martin, Uta Kunter, Peter Boor, Erawan Borkham-Kamphorst
Publikováno v:
The American Journal of Pathology. 180:1979-1990
In contrast to factors that promote mesangial cell proliferation, little is known about their endogenous inhibitors. During experimental mesangioproliferative nephritis, expression of the glomerular CCN3 (nephroblastoma overexpressed gene [ NOV ]) ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10705073a01a07a15ee2fc759634bc5d
https://doi.org/10.1016/j.ajpath.2012.01.031
https://doi.org/10.1016/j.ajpath.2012.01.031