Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ina Sulkaj"'
Type I interferons augment regulatory T cell polarization in concert with ancillary cytokine signals
Autor:
Siawosh K. Eskandari, Hazim Allos, Jenelle M. Safadi, Ina Sulkaj, Jan S. F. Sanders, Paolo Cravedi, Irene M. Ghobrial, Stefan P. Berger, Jamil R. Azzi
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
In the transplant community, research efforts exploring endogenous alternatives to inducing tolerogenic allo-specific immune responses are much needed. In this regard, CD4 + FoxP3+ regulatory T cells (Tregs) are appealing candidates due to their intr
Externí odkaz:
https://doaj.org/article/b50d639c88f04efb89352c7184a93f92
Autor:
Siawosh K. Eskandari, Hazim Allos, Basmah S. Al Dulaijan, Gandolina Melhem, Ina Sulkaj, Juliano B. Alhaddad, Anis J. Saad, Christa Deban, Philip Chu, John Y. Choi, Branislav Kollar, Bohdan Pomahac, Leonardo V. Riella, Stefan P. Berger, Jan S. F. Sanders, Judy Lieberman, Li Li, Jamil R. Azzi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T cells (Tregs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. Nevertheless, the clinical efficacy of human Tregs in patients has b
Externí odkaz:
https://doaj.org/article/bf198d45ad224883b3b5ae64e9a8c7c8
Autor:
Cheryl Brandenburg, Jean-Jacques Soghomonian, Kunzhong Zhang, Ina Sulkaj, Brianna Randolph, Marissa Kachadoorian, Gene J. Blatt
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Autism spectrum disorder (ASD) is behaviorally defined and diagnosed by delayed and/or impeded language, stereotyped repetitive behaviors, and difficulties with social interactions. Additionally, there are disruptions in motor processing, which inclu
Externí odkaz:
https://doaj.org/article/15b1a54dbee44bf983aa308f1fce9b4a
Autor:
Leyuan Ma, Duncan M. Morgan, Ina Sulkaj, Parisa Yousefpour, Charles A. Whittaker, Wuhbet Abraham, Na Li, J. Christopher Love, Darrell J. Irvine
Chimeric Antigen Receptor (CAR) T-cell therapy can be effective in treating human cancer but loss of the antigen recognized by the CAR poses a major obstacle. Here, we report an approach for vaccine boosting CAR T-cells, which triggers engagement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb058a8f4ae2d3ca55ffac5e154b663
https://doi.org/10.1101/2022.10.05.511036
https://doi.org/10.1101/2022.10.05.511036
Autor:
Amr Mansouri, Siawosh K. Eskandari, Harvey Cantor, John Choi, Jamil Azzi, Melissa Y. Yeung, Eman Alhussain, Saif A. Muhsin, Songjie Cai, Hye-Jung Kim, Hazim Allos, Jean Pierre Assaker, Marc A. Seelen, Ina Sulkaj, Juliano B. Alhaddad
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 6042-6046. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 6042-6046. NATL ACAD SCIENCES
Induction of longstanding immunologic tolerance is essential for survival of transplanted organs and tissues. Despite recent advances in immunosuppression protocols, allograft damage inflicted by antibody specific for donor organs continues to repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4aab0f7766f03dd6c030f39ad91f27
https://doi.org/10.1073/pnas.1918950117
https://doi.org/10.1073/pnas.1918950117
Autor:
Yousef Haik, Henri G. D. Leuvenink, Juliano B. Alhaddad, Li Tang, Marc A. Seelen, Songjie Cai, Ina Sulkaj, Bakhos A. Tannous, John Choi, Na Li, Darrell J. Irvine, Jamil Azzi, Arach S. Eskandari, Jean Pierre Assaker, Siawosh K. Eskandari, Amr Mansouri, Leonardo V. Riella, Hazim Allos, Mariane B. Melo, Max Zinter, Willem J. van Son, Branislav Kollar, Thiago J Borges, Bohdan Pomahac, Basmah S. Al Dulaijan
Publikováno v:
Science Translational Medicine, 12(569):4744, 1-16. AMER ASSOC ADVANCEMENT SCIENCE
Adoptive cell transfer of ex vivo expanded regulatory T cells (T-r(egs)) has shown immense potential in animal models of auto- and alloimmunity. However, the effective translation of such T-reg therapies to the clinic has been slow. Because T-reg hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b533ccd15beae2291f33c01c12057052
https://infoscience.epfl.ch/record/282085
https://infoscience.epfl.ch/record/282085