Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ina Patties"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Tucatinib (TUC), a HER2-directed tyrosine kinase inhibitor, is the first targeted drug demonstrating intracranial efficacy and significantly prolonged survival in metastatic HER2-positive breast cancer (BC) patients with brain met
Externí odkaz:
https://doaj.org/article/9cf7e6b94efd4a4a95a977a74d3e3670
Publikováno v:
Molecules, Vol 28, Iss 5, p 2008 (2023)
Radiochemotherapy-associated leuco- or thrombocytopenia is a common complication, e.g., in head and neck cancer (HNSCC) and glioblastoma (GBM) patients, often compromising treatments and outcomes. Currently, no sufficient prophylaxis for hematologica
Externí odkaz:
https://doaj.org/article/5e2966f6da8d48708fcc39c276e8c403
Autor:
Ina Patties, Sonja Kallendrusch, Lisa Böhme, Eva Kendzia, Henry Oppermann, Frank Gaunitz, Rolf-Dieter Kortmann, Annegret Glasow
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Glioblastoma is the most common and aggressive brain tumour in adults with a median overall survival of only 14 months after standard therapy with radiation therapy (IR) and temozolomide (TMZ). In a novel multimodal treatment appr
Externí odkaz:
https://doaj.org/article/3e5fedde859f4e2caead25268b769921
Publikováno v:
Molecules, Vol 27, Iss 11, p 3384 (2022)
Multimodal treatment adding immunotherapy and photodynamic treatment (PDT) to standard therapy might improve the devastating therapeutic outcome of glioblastoma multiforme patients. As a first step, we provide investigations to optimize dendritic cel
Externí odkaz:
https://doaj.org/article/7599a11fff804ccdb6f8fda29cb872dc
Autor:
Marieke Gringmuth, Jenny Walther, Sebastian Greiser, Magali Toussaint, Benjamin Schwalm, Marcel Kool, Rolf-Dieter Kortmann, Annegret Glasow, Ina Patties
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3815 (2022)
Children with high-risk SHH/TP53-mut and Group 3 medulloblastoma (MB) have a 5-year overall survival of only 40%. Innovative approaches to enhance survival while preventing adverse effects are urgently needed. We investigated an innovative therapy ap
Externí odkaz:
https://doaj.org/article/5af009a681794e13ac66563d68719e96
Autor:
Annegret Glasow, Ina Patties, Nicholas D. Priest, Ronald E. J. Mitchel, Guido Hildebrandt, Katrin Manda
Publikováno v:
Cells, Vol 10, Iss 11, p 3251 (2021)
Anti-inflammatory low-dose therapy is well established, whereas the immunomodulatory impact of doses below 0.1 Gy is much less clear. In this study, we investigated dose, dose rate and time-dependent effects in a dose range of 0.005 to 2 Gy on immune
Externí odkaz:
https://doaj.org/article/1da165c7c1974c26970ed2de992897c2
Publikováno v:
Cells, Vol 9, Iss 12, p 2595 (2020)
Focused ultrasound (FUS) has become an important non-invasive therapy for solid tumor ablation via thermal effects. The cavitation effect induced by FUS is thereby avoided but applied for lithotripsy, support drug delivery and the induction of blood
Externí odkaz:
https://doaj.org/article/33162d8cc027473da9d7cb2902b5da67
Autor:
Johanna Scholbach, Anett Schulz, Florian Westphal, Dietmar Egger, Anja Kathrin Wege, Ina Patties, Margarethe Köberle, Ulrich Sack, Franziska Lange
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46772 (2012)
To study the function and maturation of the human hematopoietic and immune system without endangering individuals, translational human-like animal models are needed. We compare the efficiency of CD34(+) stem cells isolated from cryopreserved cord blo
Externí odkaz:
https://doaj.org/article/f8f97afd68eb45e280283c83989c339c
Publikováno v:
Cells
Volume 9
Issue 12
Cells, Vol 9, Iss 2595, p 2595 (2020)
Volume 9
Issue 12
Cells, Vol 9, Iss 2595, p 2595 (2020)
Focused ultrasound (FUS) has become an important non-invasive therapy for solid tumor ablation via thermal effects. The cavitation effect induced by FUS is thereby avoided but applied for lithotripsy, support drug delivery and the induction of blood
Publikováno v:
Klinische Pädiatrie.