Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ina Mexhitaj"'
Autor:
Simone C Wuest, Ina Mexhitaj, Noo Ri Chai, Elena Romm, Joerg Scheffel, Biying Xu, Kelly Lane, Tianxia Wu, Bibiana Bielekova
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105434 (2014)
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS). Neither the antigenic target(s) nor the cell population(s) responsible for CNS tissue destruction in MS have been fully defined. The objective of this stu
Externí odkaz:
https://doaj.org/article/b61874044f8a4426b9370abf84d20954
Autor:
Koji Shinoda, Rui Li, Ayman Rezk, Ina Mexhitaj, Kristina R. Patterson, Mihir Kakara, Leah Zuroff, Jeffrey L. Bennett, H.-Christian von Büdingen, Robert Carruthers, Keith R. Edwards, Robert Fallis, Paul S. Giacomini, Benjamin M. Greenberg, David A. Hafler, Carolina Ionete, Ulrike W. Kaunzner, Christopher B. Lock, Erin E. Longbrake, Gabriel Pardo, Fredrik Piehl, Martin S. Weber, Tjalf Ziemssen, Dina Jacobs, Jeffrey M. Gelfand, Anne H. Cross, Briana Cameron, Bruno Musch, Ryan C. Winger, Xiaoming Jia, Christopher T. Harp, Ann Herman, Amit Bar-Or
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 3
A small proportion of multiple sclerosis (MS) patients develop new disease activity soon after starting anti-CD20 therapy. This activity does not recur with further dosing, possibly reflecting deeper depletion of CD20-expressing cells with repeat inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384a4285b60b8efee3e53099aac80957
https://escholarship.org/uc/item/2nb3w4bz
https://escholarship.org/uc/item/2nb3w4bz
Autor:
Mihir Kakara, Dina A. Jacobs, Scott E. Hensley, Diego A. Espinoza, Kerry Lenzi, Ayman Rezk, Paul Bates, Ina Mexhitaj, Michael R. Betts, Daniel M. Markowitz, E. John Wherry, Kristina R. Patterson, Divij Mathew, Daniela Weiskopf, Sigrid Gouma, Allison R. Greenplate, Rishi R. Goel, Eline T. Luning Prak, Jessy C. Kadri, Amit Bar-Or, Alessandro Sette, Kendall A. Lundgreen, Sokratis A. Apostolidis, Alba Grifoni, Rui Li, Clyde E. Markowitz, Allison Babb, Mark M Painter
Publikováno v:
Nature Medicine
SARS-CoV-2 messenger RNA vaccination in healthy individuals generates immune protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine-induced responses in immunosuppressed patients. We investigated induction of antigen-spec
Autor:
Ayal Rozenberg, Brenda Banwell, Julia O'Mahony, Trina A. Johnson, Heather Hanwell, Luke M. Healy, Alexander W Saveriano, Ina Mexhitaj, Mukanthu Nyirenda, Giulia Fadda, Rui Li, Douglas L. Arnold, Craig S. Moore, Shannon E. Dunn, Amit Bar-Or, Chahrazed Belabani, E. Ann Yeh, Laurence Poliquin-Lasnier, Ruth Ann Marrie
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 27(12)
Background: Being obese is associated with both increased risk of developing multiple sclerosis (MS) and greater MS disease activity. Objectives: The objective of this study is to investigate levels and potential pathophysiologic contribution of seru
Autor:
Diego A Espinoza, Ina Mexhitaj, Jacqueline Smiler, Fernanda Mafra, Renata Pellegrino Da Silva, Giulia Fadda, E Ann Yeh, Ruth Ann Marrie, Douglas L Arnold, Rui Li, Brenda Banwell, Amit Bar-Or
Publikováno v:
The Journal of Immunology. 208:108.04-108.04
Approximately 20–30% of children presenting with acquired inflammatory demyelinating syndromes (ADS) have multiple sclerosis (MS). Another 30% harbor serum antibodies against myelin oligodendrocyte glycoprotein and are referred to as having MOG-ass
Autor:
Ina Mexhitaj, Ruth Ann Marrie, Trina A. Johnson, Dessa Sadovnick, Ayman Rezk, Amit Bar-Or, D. Louis Collins, Douglas L. Arnold, Ayal Rozenberg, Brenda Banwell, Julia O'Mahony, Craig S. Moore, Rui Li, Mukanthu Nyirenda, Bruno Gran, E. Ann Yeh
Publikováno v:
Brain : a journal of neurology. 142(3)
Elucidation of distinct T-cell subsets involved in multiple sclerosis immune-pathophysiology continues to be of considerable interest since an ultimate goal is to more selectively target the aberrant immune response operating in individual patients.
Autor:
A. Chowdhury, L. Baker, Jesus A. Angulo, Ingrid Tulloch, H. Payne, Ina Mexhitaj, L. Afanador, Dalila G. Ordonez, E. Olivares
Publikováno v:
Neurotoxicity Research. 26:115-129
Methamphetamine (METH) causes significant loss of some striatal projection and interneurons. Recently, our group reported on the proliferation of new cells 36 h after METH and some of the new cells survive up to 12 weeks (Tulloch et al., Neuroscience
Autor:
Arturo G. GarzaGongora, Nane Ghazaryan, Ingrid Tulloch, Lauriaselle Afanador, Jesus A. Angulo, Ina Mexhitaj
Publikováno v:
Neuroscience. 193:162-169
Methamphetamine (METH) is an addictive agent that poses a public health problem due to its toxic effects on neural tissue. We have shown that METH induces striatal lesions (cell loss) within 24 h of administration. Because cell proliferation has been
T-cell antigens in pediatric-onset multiple sclerosis: A unique window into early disease mechanisms
Autor:
Ina Mexhitaj, Mukanthu Nyirenda, Douglas L Arnold, Ruth Ann Marrie, Brenda Banwell, Amit Bar-Or
Publikováno v:
The Journal of Immunology. 198:210.7-210.7
Multiple sclerosis (MS) involves immune attacks on the CNS, leading to demyelination, axonal injury and increasing neurological dysfunction. Though T cells are implicated, the particular subsets and their antigenic targets remain unknown. In adult-on
Autor:
Irene Cortese, Elena Romm, Peter R. Williamson, Bibiana Bielekova, Yen Chih Lin, Tianxia Wu, Sungpil Han, Adriana Marques, Joan Ohayon, Raphaela Goldbach-Mansky, Adeline Vanderver, Alan D. Salgado, Camilo Toro, Ina Mexhitaj, Simone C. Wuest
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(6)
We performed unbiased, comprehensive immunophenotyping of cerebrospinal fluid (CSF) and blood leukocytes in 221 subjects referred for the diagnostic work-up of neuroimmunological disorders to obtain insight about disease-specific phenotypes of intrat