Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ina M. Berger"'
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167306 (2016)
The molecular mechanisms that regulate cardiomyocyte proliferation during embryonic heart growth are not completely deciphered yet. In a forward genetic N-ethyl-N-nitrosourea (ENU) mutagenesis screen, we identified the recessive embryonic-lethal zebr
Externí odkaz:
https://doaj.org/article/1f7eedb37c194447803a3d6f4f8af36d
Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish
Autor:
Karen S. Frese, Wolfgang Rottbauer, Steffen Just, Tillman Dahme, Susanne Rinné, Mirjam Keßler, Sarah Bock, Alexander Pott, Ina M. Berger, Niels Decher
Publikováno v:
Journal of Molecular and Cellular Cardiology. 120:42-52
The genetic underpinnings that orchestrate the vertebrate heart rate are not fully understood yet, but of high clinical importance, since diseases of cardiac impulse formation and propagation are common and severe human arrhythmias. To identify novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d04ad9fc1a3af98475a4154fe8055ec4
https://doi.org/10.1016/j.yjmcc.2018.05.005
https://doi.org/10.1016/j.yjmcc.2018.05.005
Publikováno v:
Progress in biophysics and molecular biology. 138
The molecular mechanism essential for the formation of heart valves involves complex interactions of signaling molecules and transcription factors. The Mediator Complex (MC) functions as multi-subunit machinery to orchestrate gene transcription, espe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98197e0be07d429181c3c49731333e82
https://pubmed.ncbi.nlm.nih.gov/30036562
https://pubmed.ncbi.nlm.nih.gov/30036562
Autor:
Alexander, Pott, Sarah, Bock, Ina M, Berger, Karen, Frese, Tillman, Dahme, Mirjam, Keßler, Susanne, Rinné, Niels, Decher, Steffen, Just, Wolfgang, Rottbauer
Publikováno v:
Journal of molecular and cellular cardiology. 120
The genetic underpinnings that orchestrate the vertebrate heart rate are not fully understood yet, but of high clinical importance, since diseases of cardiac impulse formation and propagation are common and severe human arrhythmias. To identify novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f013da2131b161c396b65d3f37c4fb9
https://pubmed.ncbi.nlm.nih.gov/29750993
https://pubmed.ncbi.nlm.nih.gov/29750993
Autor:
Derk Frank, Wolfgang Rottbauer, Sebastian Spaich, Rainer Will, Norbert Frey, Ina M. Berger, Steffen Just, Christian Kuhn, Manfred Koegl, Johannes Backs, Saskia Spaich, Hugo A. Katus, Stefan Wiemann, Bernhard Korn
Publikováno v:
Circulation Research. 111:1504-1516
Rationale: The emerging role of the ubiquitin–proteasome system in cardiomyocyte function and homeostasis implies the necessity of tight regulation of protein degradation. However, little is known about cardiac components of this machinery. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50157068916192c7c068f795de86f803
https://doi.org/10.1161/circresaha.112.271007
https://doi.org/10.1161/circresaha.112.271007
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167306 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167306 (2016)
The molecular mechanisms that regulate cardiomyocyte proliferation during embryonic heart growth are not completely deciphered yet. In a forward genetic N-ethyl-N-nitrosourea (ENU) mutagenesis screen, we identified the recessive embryonic-lethal zebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4855c3f3e70f5b45fa50f3478f7292b0
https://pubmed.ncbi.nlm.nih.gov/27907103
https://pubmed.ncbi.nlm.nih.gov/27907103
Publikováno v:
Biochemical and biophysical research communications. 477(4)
In search for novel key regulators of cardiac valve formation, we isolated the zebrafish cardiac valve mutant ping pong (png). We find that an insertional promoter mutation within the zebrafish mediator complex subunit 10 (med10) gene is leading to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691c432059a30371746d0977d46ca1ff
https://pubmed.ncbi.nlm.nih.gov/27343557
https://pubmed.ncbi.nlm.nih.gov/27343557
Autor:
Nicole Trano, Ina M. Berger, Sabine Marquart, Uwe Strähle, Mark C. Fishman, David Hassel, Benjamin Meder, Christelle Etard, Wolfgang Rottbauer, Britta Vogel, Eva Patzel, Hugo A. Katus, Tillman Dahme, Steffen Just
Publikováno v:
Journal of Cell Science; Vol 124
Journal of Cell Science
Journal of Cell Science
Assembly, maintenance and renewal of sarcomeres require highly organized and balanced folding, transport, modification and degradation of sarcomeric proteins. However, the molecules that mediate these processes are largely unknown. Here, we isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6434c4ab1aba59cd9686adb51a2f6c68
Autor:
Sabrina Weber, Britta Vogel, Hugo A. Katus, Wolfgang Rottbauer, Steffen Just, Benjamin Meder, Ina M. Berger, Christina Laufer
Publikováno v:
Biochemical and Biophysical Research Communications. 390:516-522
Due to lack of families suitable for linkage analysis and positional cloning most of the genetic causes of human dilated cardiomyopathy (DCM) are still unknown. To facilitate rapid identification and validation of novel DCM disease genes appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1ccaaf7dc3cf6f0adaeade2fccc5b7
https://doi.org/10.1016/j.bbrc.2009.09.129
https://doi.org/10.1016/j.bbrc.2009.09.129
Autor:
Ina M. Berger, Gerhard Mittler, Hans A. Kestler, Robert Liefke, Kerstin Hein, Wiebke Cizelsky, Franz Oswald, Steffen Just, Michael Kühl, Tilman Borggrefe, J. Eric Sträng, Francesca Ferrante
Publikováno v:
Science Signaling. 8
Physiologically, Notch signal transduction plays a pivotal role in differentiation; pathologically, Notch signaling contributes to the development of cancer. Transcriptional activation of Notch target genes involves cleavage of the Notch receptor in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee55c9e630097ac7dbd061f6310e335
https://doi.org/10.1126/scisignal.2005892
https://doi.org/10.1126/scisignal.2005892