Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ina Hess"'
Autor:
Anja Uhmann, Hannah Niemann, Bérénice Lammering, Cornelia Henkel, Ina Heß, Albert Rosenberger, Christian Dullin, Anke Schraepler, Walter Schulz-Schaeffer, Heidi Hahn
Publikováno v:
Sarcoma, Vol 2012 (2012)
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Aberrant Hedgehog (Hh) signaling is characteristic of the embryonal subtype (ERMS) and of fusion-negative alveolar RMS. In the mouse, ERMS-like tumors can be induced by mutati
Externí odkaz:
https://doaj.org/article/3100406bbcff47c592602d9a5a6118f4
Autor:
Heidi Hahn, Olaf Witt, Walter Schulz-Schaeffer, Leszek Wojnowski, Frauke Nitzki, Anja Uhmann, Steven A. Johnsen, Judith Pirngruber, Sarah Kimmina, Christian Dullin, Ina Hess, Sven Mönkemeyer, Svantje Tauber, Albert Rosenberger, Frauke Petry, Ines Ecke
Supplementary Table 1 from Antitumor Effects of a Combined 5-Aza-2′Deoxycytidine and Valproic Acid Treatment on Rhabdomyosarcoma and Medulloblastoma in Ptch Mutant Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f1d0caf89683250cd0a8a0c6af3fce
https://doi.org/10.1158/0008-5472.22380788.v1
https://doi.org/10.1158/0008-5472.22380788.v1
Autor:
Heidi Hahn, Olaf Witt, Walter Schulz-Schaeffer, Leszek Wojnowski, Frauke Nitzki, Anja Uhmann, Steven A. Johnsen, Judith Pirngruber, Sarah Kimmina, Christian Dullin, Ina Hess, Sven Mönkemeyer, Svantje Tauber, Albert Rosenberger, Frauke Petry, Ines Ecke
Patched (Ptch) heterozygous mice develop medulloblastoma (MB) and rhabdomyosarcoma (RMS) resembling the corresponding human tumors. We have previously shown that epigenetic silencing of the intact Ptch allele contributes to tumor formation in this mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87399f4225770ce74bf9daf8be16a622
https://doi.org/10.1158/0008-5472.c.6499676.v1
https://doi.org/10.1158/0008-5472.c.6499676.v1
Autor:
Ina Heß, Arne Zibat, Rolf Buslei, Nadine Brandes, Alexander Wolff, Anke Frommhold, Dominik Simon Botermann, Anja Uhmann, Heidi Hahn
Publikováno v:
The Journal of Endocrinology
Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b730f5c6c2e1829db5b01d96271fa2d9
https://doi.org/10.1530/joe-20-0388
https://doi.org/10.1530/joe-20-0388
Autor:
Anna Müllen, Heidi Hahn, Anke Frommhold, Dominik Simon Botermann, Anja Uhmann, Slavica Hristomanova Mitkovska, Sebastian Zabel, Nadine Brandes, Hanna Scheile, Ina Heß, Wiebke Maurer
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9295, p 9295 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences
Volume 21
Issue 23
Basal cell carcinoma (BCC) originate from Hedgehog/Patched signaling-activated epidermal stem cells. However, the chemically induced tumorigenesis of mice with a CD4Cre-mediated biallelic loss of the Hedgehog signaling repressor Patched also induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825a8ec585826c5ec22abd42c4614b0e
https://www.mdpi.com/1422-0067/21/23/9295
https://www.mdpi.com/1422-0067/21/23/9295
Autor:
D Schult, Annett Hölsken, Anja Uhmann, Michael Buchfelder, Rolf Buslei, Ina Heß, Heidi Hahn, Joanna Pyczek
Publikováno v:
Scientific Reports
Hedgehog (HH) signaling is known to be essential during the embryonal development of the pituitary gland but the knowledge about its role in the adult pituitary and in associated tumors is sparse. In this report we investigated the effect of excess H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8bbc1ac203181b9a9d234acb62b781
Autor:
Frauke Nitzki, Nicole Prüfer, Frank Strutz, Albert Rosenberger, Heidi Hahn, Anne Fritsch, Walter J. Schulz-Schaeffer, Torsten Pietsch, Bérénice Lammering, Stefan Schweyer, Anke Schraepler, Christian Dullin, Cornelia Henkel, Ina Hess, Anja Uhmann, Hannah Niemann, Julia Reifenberger
Publikováno v:
Molecular Cancer Therapeutics. 10:2179-2188
Activation of the Hedgehog (Hh)-signaling pathway due to deficiency in the Hh receptor Patched1 (Ptch) is the pivotal defect leading to formation of basal cell carcinoma (BCC). Recent reports provided evidence of Ptch-dependent secretion of vitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286b2c611969cfa055fe7e36521822e9
https://doi.org/10.1158/1535-7163.mct-11-0422
https://doi.org/10.1158/1535-7163.mct-11-0422
Autor:
Steven A. Johnsen, Judith Pirngruber, Heidi Hahn, Olaf Witt, Leszek Wojnowski, Svantje Tauber, Sarah Kimmina, Ina Hess, Frauke Petry, Sven Mönkemeyer, Anja Uhmann, Frauke Nitzki, Walter J. Schulz-Schaeffer, Christian Dullin, Albert Rosenberger, Ines Ecke
Publikováno v:
Cancer Research. 69:887-895
Patched (Ptch) heterozygous mice develop medulloblastoma (MB) and rhabdomyosarcoma (RMS) resembling the corresponding human tumors. We have previously shown that epigenetic silencing of the intact Ptch allele contributes to tumor formation in this mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1082011fb770c80922a1a4be06b985cf
https://doi.org/10.1158/0008-5472.can-08-0946
https://doi.org/10.1158/0008-5472.can-08-0946
Autor:
Anke Frommhold, Simone König, Heidi Hahn, Anja Uhmann, Hans Christiansen, Kai Dittmann, Julia Reifenberger, Ina Heß, Frauke Nitzki, Sebastian Zabel, Walter J. Schulz-Schaeffer, Fred Lühder
Publikováno v:
The Journal of investigative dermatology. 134(10)
The development of basal cell carcinoma (BCC), the most frequently diagnosed tumor among persons with European ancestry, is closely linked to mutations in the Hedgehog (Hh) receptor and tumor suppressor Patched1 (Ptch). Using Ptch(flox/flox)CD4Cre(+/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81995a9f8b697c60a04f5981825f5fe6
https://pubmed.ncbi.nlm.nih.gov/25219650
https://pubmed.ncbi.nlm.nih.gov/25219650
Autor:
Hans Christiansen, Avinash Bhandoola, Jens van den Brandt, Holger M. Reichardt, Jürgen Wienands, Anja Uhmann, Ina Heß, Claudia Binder, Ralf Dressel, Kai Dittmann, Heidi Hahn, Martin Fassnacht, Fred Lühder
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(6)
We recently described that T cell specification in mice deficient in the Hedgehog (Hh) receptor Patched (Ptch) is blocked at the level of the common lymphoid progenitor in the bone marrow (BM). Adoptive transfer of wild-type BM in Ptch-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c9f411bf748fa0b193c53277171812
https://pubmed.ncbi.nlm.nih.gov/21317383
https://pubmed.ncbi.nlm.nih.gov/21317383