Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ina Baļķe"'
Autor:
Jan M. Sobczak, Irena Barkovska, Ina Balke, Dominik A. Rothen, Mona O. Mohsen, Dace Skrastina, Anete Ogrina, Byron Martina, Juris Jansons, Janis Bogans, Monique Vogel, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Vaccines, Vol 12, Iss 6, p 661 (2024)
T help (Th), stimulation of toll-like receptors (pathogen-associated molecular patterns, PAMPs), and antigen organization and repetitiveness (pathogen-associated structural patterns, PASPs) were shown numerous times to be important in driving B-cell
Externí odkaz:
https://doaj.org/article/dd21e3c1a8eb4f19965421a98dc62725
Autor:
Romano Josi, Anete Ogrina, Dominik Rothen, Ina Balke, Arnau Solé Casaramona, Simone de Brot, Mona O. Mohsen
Publikováno v:
Vaccines, Vol 12, Iss 4, p 355 (2024)
The tumor-draining lymph nodes (tdLN) are the initial site of metastases and are the prime site for generating robust antitumor responses. In this study, we explored the efficacy of a universal immune activator (ImmAct) targeted to the tdLN. This app
Externí odkaz:
https://doaj.org/article/7d734c7def9141d993ad6e77a9dc3a0e
Autor:
Anete Ogrina, Ina Balke, Ieva Kalnciema, Dace Skrastina, Juris Jansons, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Virus-like particles (VLPs) are virus-derived artificial nanostructures that resemble a native virus-stimulating immune system through highly repetitive surface structures. Improved safety profiles, flexibility in vaccine construction, and the ease o
Externí odkaz:
https://doaj.org/article/f31428eeb5c1404bb725f2cbd812544c
Autor:
Ina Balke, Ivars Silamikelis, Ilze Radovica-Spalvina, Vilija Zeltina, Gunta Resevica, Davids Fridmanis, Andris Zeltins
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0287278 (2023)
Ryegrass mottle virus (RGMoV; genus: Sobemovirus) is a single-stranded positive RNA virus with a 30 nm viral particle size. It exhibits T = 3 symmetry with 180 coat protein (CP) subunits forming a viral structure. The RGMoV genome comprises five open
Externí odkaz:
https://doaj.org/article/b56e7d40369145e4addb04e49b2c036b
Autor:
Mona O. Mohsen, Dominik Rothen, Ina Balke, Byron Martina, Vilija Zeltina, Varghese Inchakalody, Zahra Gharailoo, Gheyath Nasrallah, Said Dermime, Kaspars Tars, Monique Vogel, Andris Zeltins, Martin F. Bachmann
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). VLPs are safe vacci
Externí odkaz:
https://doaj.org/article/75e90d2e660e4495962a2ced6e6426ae
Autor:
Gints Kalnins, Rebeka Ludviga, Ieva Kalnciema, Gunta Resevica, Vilija Zeltina, Janis Bogans, Kaspars Tars, Andris Zeltins, Ina Balke
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5347 (2023)
Sobemoviruses encode serine-like 3C proteases (Pro) that participate in the processing and maturation of other virus-encoded proteins. Its cis and trans activity is mediated by the naturally unfolded virus-genome-linked protein (VPg). Nuclear magneti
Externí odkaz:
https://doaj.org/article/8b2dbe7c2360493eb626a31fcdf68403
Autor:
Ina Balke, Vilija Zeltina, Nikita Zrelovs, Ieva Kalnciema, Gunta Resevica, Rebeka Ludviga, Juris Jansons, Inga Moročko-Bičevska, Dalija Segliņa, Andris Zeltins
Publikováno v:
Microorganisms, Vol 10, Iss 10, p 1933 (2022)
The agricultural importance of sea buckthorn (SBT; Hippophae rhamnoides L.) is rapidly increasing. Several bacterial and fungal pathogens infecting SBT have been identified and characterized; however, the viral pathogens are not yet known. In this st
Externí odkaz:
https://doaj.org/article/d21730c48ac04958887d42fedb97a16e
Autor:
Anete Ogrina, Dace Skrastina, Ina Balke, Ieva Kalnciema, Juris Jansons, Martin F. Bachmann, Andris Zeltins
Publikováno v:
Vaccines, Vol 10, Iss 4, p 485 (2022)
Plant-based virus-like particle (VLP) vaccines have been studied for years, demonstrating their potential as antigen-presenting platforms. In this paper, we describe the development of, and compare between, simple Escherichia coli-based antigen displ
Externí odkaz:
https://doaj.org/article/d5bd9c9df3f8453b8c394cc5bef41de3
Autor:
Ina Balke, Andris Zeltins
Publikováno v:
Viruses, Vol 12, Iss 3, p 270 (2020)
Vaccination is one of the most effective public health interventions of the 20th century. All vaccines can be classified into different types, such as vaccines against infectious diseases, anticancer vaccines and vaccines against autoimmune diseases.
Externí odkaz:
https://doaj.org/article/bcd134665a0f4ef9bb2af80340119681
Autor:
Andris Zeltins, Māris Turks, Dace Skrastina, Jevgeņija Lugiņina, Ieva Kalnciema, Ina Balke, Ērika Bizdēna, Vitalijs Skrivelis
Publikováno v:
Antibiotics, Vol 6, Iss 3, p 18 (2017)
Milbemycins are macrolide antibiotics with a broad spectrum of nematocidal, insecticidal, and acaricidal activity. To obtain milbemycin A3/A4 derivatives suitable for chemical conjugation to protein carriers (milbemycin haptens), succinate linker and
Externí odkaz:
https://doaj.org/article/f5adf815792845f0b0d9ee1dd959b371