Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

Autor: Jiwen Li, Lin Pan, William G. Pembroke, Jessica E. Rexach, Marlesa I. Godoy, Michael C. Condro, Alvaro G. Alvarado, Mineli Harteni, Yen-Wei Chen, Linsey Stiles, Angela Y. Chen, Ina B. Wanner, Xia Yang, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum, Ye Zhang

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)

Astrocytes are important players in brain development, homeostasis, and disease. Here, the authors compare the transcriptional profiles of human and mouse astrocytes. They report species-specific susceptibility to oxidative stress and response to hyp

Externí odkaz: https://doaj.org/article/80da4dfa224845c2a806b159e42df65d

Reactive astrocyte nomenclature, definitions, and future directions

Autor: Arthur M. Butt, Elena Galea, Richard M. Ransohoff, Raymond A. Swanson, Eduardo R. Zimmer, Christopher M. Norris, Gilles Bonvento, Andras Lakatos, Philip G. Haydon, Wei Ting Chen, Christine R. Rose, Alexey Semyanov, Nicola J. Allen, Anna V. Molofsky, Javier Vitorica, Seiji Okada, Alfonso Araque, Antonia Gutierrez, Masamitsu Iino, Alberto Serrano-Pozo, Vittorio Gallo, C. Justin Lee, Magdalena Götz, Baljit S. Khakh, Christian Steinhäuser, Bart De Strooper, Stéphane H. R. Oliet, Andrea Volterra, Swetlana Sirko, Kira E. Poskanzer, Michael V. Sofroniew, Giorgio Carmignoto, Elly M. Hol, Frank W. Pfrieger, Beatriz G. Pérez-Nievas, Ksenia V. Kastanenka, Keith K. Murai, James P. O'Callaghan, Ina B. Wanner, David H. Rowitch, Pierre J. Magistretti, Cinthia Farina, Marcela Pekna, Albee Messing, Jia Qian Wu, Shane A. Liddelow, Dieter Henrik Heiland, Anusha Mishra, Robert Zorec, Levi B. Wood, Marc R. Freeman, Matthew Holt, Luis Barbeito, Gabor C. Petzold, Luc Pellerin, Jeffrey D. Rothstein, Nathalie Rouach, Carole Escartin, Schuichi Koizumi, Gertrudis Perea, Dwight E. Bergles, Miriam Riquelme-Perez, Martine Cohen-Salmon, Stefanie Robel, James E. Goldman, Binhai Zheng, João Filipe Oliveira, Ari Barzilai, Steven A. Goldman, Brian A. MacVicar, Aude Panatier, Helmut Kettenmann, Alexei Verkhratsky, Amit Agarwal, Colm Cunningham, Blanca Diaz-Castro, Francisco J. Quintana, Milos Pekny, Harald Sontheimer, Benjamin Deneen, Vladimir Parpura

Publikováno v: Nature neuroscience 24(3), 312-325 (2021). doi:10.1038/s41593-020-00783-4
Escartin, C, Galea, E, Lakatos, A, O'Callaghan, J P, Petzold, G C, Serrano-Pozo, A, Steinhauser, C, Volterra, A, Carmignoto, G, Agarwal, A, Allen, N J, Araque, A, Barbeito, L, Barzilai, A, Bergles, D E, Bonvento, G, Butt, A M, Chen, W-T, Cohen-Salmon, M, Cunningham, C, Deneen, B, De Strooper, B, Diaz-Castro, B, Farina, C, Freeman, M, Gallo, V, Goldman, J E, Goldman, S A, Gotz, M, Gutierrez, A, Haydon, P G, Heiland, D H, Hol, E M, Holt, M G, Iino, M, Kastanenka, K V, Kettenmann, H, Khakh, B S, Koizumi, S, Lee, C J, Liddelow, S A, MacVicar, B A, Magistretti, P, Messing, A, Mishra, A, Molofsky, A V, Murai, K K, Norris, C M, Okada, S, Oliet, S H R, Oliveira, J F, Panatier, A, Parpura, V, Pekna, M, Pekny, M, Pellerin, L, Perea, G, Perez-Nievas, B G, Pfrieger, F W, Poskanzer, K E, Quintana, F J, Ransohoff, R M, Riquelme-Perez, M, Robel, S, Rose, C R, Rothstein, J D, Rouach, N, Rowitch, D H, Semyanov, A, Sirko, S, Sontheimer, H, Swanson, R A, Vitorica, J, Wanner, I-B, Wood, L B, Wu, J, Zheng, B, Zimmer, E R, Zorec, R, Sofroniew, M V & Verkhratsky, A 2021, ' Reactive astrocyte nomenclature, definitions, and future directions ', Nature Neuroscience, vol. 24, pp. 312–325 . https://doi.org/10.1038/s41593-020-00783-4
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2021, 24 (3), pp.312-325. ⟨10.1038/s41593-020-00783-4⟩
Nat Neurosci
Nature Neuroscience, Nature Publishing Group, 2021, 24, pp.312-325. ⟨10.1038/s41593-020-00783-4⟩
Nature neuroscience, vol 24, iss 3
Nature Neuroscience, 2021, 24, pp.312-325. ⟨10.1038/s41593-020-00783-4⟩
Escartin, C, Galea, E, Lakatos, A, O'Callaghan, J P, Petzold, C C, Serrano-Pozo, A, Steinhauser, C, Volterra, A, Carmignoto, G, Agarwal, A, Allen, N J, Araque, A, Barbeito, L, Barzilai, A, Bergles, D E, Bonvento, G, Butt, A M, Chen, W-T, Cohen-Salmon, M, Cunningham, C, Deneen, B, De Strooper, B, Diaz-Castro, B, Farina, C, Freeman, M, Gallo, V, Goldman, J E, Goldman, S A, Gotz, M, Gutierrez, A, Haydon, P G, Heiland, D H, Hol, E M, Holt, M G, Iino, M, Kastanenka, K V, Kettenmann, H, Khakh, B S, Koizumi, S, Lee, C J, Liddelow, S A, MacVicar, B A, Magistretti, P, Messing, A, Mishra, A, Molofsky, A V, Murai, K, Norris, C M, Okada, S, Oliet, S HR, Oliveira, J F, Panatier, A, Parpura, V, Pekna, M, Pekny, M, Pellerin, L, Perea, G, Perez-Nievas, B G, Pfrieger, F W, Poskanazer, K E, Quintana, F J, Ransohoff, R M, Riquelme-Perez, M, Robel, S, Rose, C R, Rothstein, J, Rouach, N, Rowitch, D H, Semyanov, A, Sirko, S, Sontheimer, H, Swanson, R A, Vitorica, J, Wanner, I-B, Wood, L B, Wu, J, Zheng, B, Zimmer, E R, Zorec, R, Sofroniew, M V & Verkhratsky, A 2021, ' Reactive astrocyte nomenclature, definitions, and future directions ', Nature Neuroscience . https://doi.org/10.1038/s41593-020-00783-4

Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was first described over a century ago, uncertainties and controversie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94bde53ce6b6eff445e92e9ff71c773

Olfactory ensheathing cell–neurite alignment enhances neurite outgrowth in scar-like cultures

Autor: Patricia E. Phelps, Rana R. Khankan, Ina B. Wanner

Publikováno v: Experimental Neurology. 269:93-101

The regenerative capacity of adult CNS neurons after injury is strongly inhibited by the spinal cord lesion site environment that is composed primarily of the reactive astroglial scar and invading meningeal fibroblasts. Olfactory ensheathing cell (OE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df86cbdee7d1e2fe74b21152424c4677
https://doi.org/10.1016/j.expneurol.2015.03.025

Inhibition of N-cadherin and β-catenin function reduces axon-induced Schwann cell proliferation

Autor: Gagani Athauda, Hartmut Halfter, Paula V. Monje, Burkhard Gess, Ina B. Wanner, Ilka Kleffner, Patrick M. Wood, Peter Young

Publikováno v: Journal of Neuroscience Research. 86:797-812

N-cadherin and beta-catenin are involved in cell adhesion and cell cycle in tumor cells and neural crest. Both are expressed at key stages of Schwann cell (SC) development, but little is known about their function in the SC lineage. We studied the ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5ea7f1629a086ef414edf7466bd0c3
https://doi.org/10.1002/jnr.21528

Role of N-cadherin in Schwann cell precursors of growing nerves

Autor: Kristjan R. Jessen, James J. Mahoney, Aman Kumar, Rhona Mirsky, Nicole K. Guerra, Ina B. Wanner, Patrick M. Wood

Publikováno v: Glia. 54:439-459

In the present paper, we determine the localization and developmental regulation of N-cadherin in embryonic rat nerves and examine the role of N-cadherin in this system. We also identify a major transition in the architecture of embryonic nerves and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b916a312d7fa01aeee6310c45ebb143
https://doi.org/10.1002/glia.20390