Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ina, Yoon"'
Autor:
Uijoo Kim, Sunkyo Hwang, Seongmin Cho, Hyeong Yun Kim, Hamin Ban, Joohee Park, Jeongwon Mun, Nayoung Kim, Ji Hun Suh, Jihye Choi, Yungyeong Shin, Sang Bum Kim, Ina Yoon, Hyuk-Sang Kwon, Sunghoon Kim
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRecent investigations have highlighted the intratumoral administration of Toll-like receptor (TLR) ligands as a promising approach to initiate localized immune responses and enhance antitumor immunity. However, the clinical application of
Externí odkaz:
https://doaj.org/article/ad2a06cf65624e5ea953860f136f6946
Autor:
Ina Yoon, Sulhee Kim, Minjae Cho, Kyung Ah You, Jonghyeon Son, Caroline Lee, Ji Hun Suh, Da‐Jeong Bae, Jong Min Kim, Sinae Oh, Songhwa Park, Sanga Kim, Seong Hyeok Cho, Seonha Park, Kyuhyeon Bang, Minjeong Seo, Jong Hyun Kim, Bongyong Lee, Joon Seok Park, Kwang Yeon Hwang, Sunghoon Kim
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 7, Pp 1-21 (2023)
Abstract Prolyl‐tRNA synthetase 1 (PARS1) has attracted much interest in controlling pathologic accumulation of collagen containing high amounts of proline in fibrotic diseases. However, there are concerns about its catalytic inhibition for potenti
Externí odkaz:
https://doaj.org/article/c423ef5903cf4af4baee1d3b57474eab
Autor:
Kibum Kim, Hee Chan Yoo, Byung Gyu Kim, Sulhee Kim, Yulseung Sung, Ina Yoon, Ya Chun Yu, Seung Joon Park, Jong Hyun Kim, Kyungjae Myung, Kwang Yeon Hwang, Sunghoon Kim, Jung Min Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Leucyl-tRNA synthetase 1 (LARS1) is a leucine sensor for mTORC1 signaling and regulates leucine utilization depending on glucose availability. Here, the author show that O-GlcNAcylation of LARS1 is crucial for its ability to regulate mTORC1 activity
Externí odkaz:
https://doaj.org/article/b24a9f59b90d4b6bb4d56ba51f1109ee
Autor:
YounHa Kim, Sang Bum Kim, Ho Lee, Doyeun Kim, Soon Sun Bak, Ina Yoon, Seongmin Cho, Seung Jae Jeong, Yoon Jeon, Jina Kim, Ji-hee Kim, Soohwan Oh, Battogtokh, Khas-Erdene, Min Chul Park, Young Kwan Sung, Sunghoon Kim
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 14, p5764-5778, 15p
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100642- (2021)
Summary: Leucyl-tRNA synthetase 1 (LARS1) synthesizes Leu-tRNALeu for protein synthesis and plays an important role in mTORC1 activation by sensing intracellular leucine concentrations. Here, we describe a protocol for the purification, reductive met
Externí odkaz:
https://doaj.org/article/f1b698979a9e4619a69c5053f7a98670
Autor:
Seung Jae Jeong, Shinhye Park, Loi T. Nguyen, Jungwon Hwang, Eun-Young Lee, Hoi-Khoanh Giong, Jeong-Soo Lee, Ina Yoon, Ji-Hyun Lee, Jong Hyun Kim, Hoi Kyoung Kim, Doyeun Kim, Won Suk Yang, Seon-Young Kim, Chan Yong Lee, Kweon Yu, Nahum Sonenberg, Myung Hee Kim, Sunghoon Kim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The initiation of translation is a highly regulated process that contributes to specific gene expression programs. Here the authors find that, in vertebrate, threonyl-tRNA synthetase (TRS) can act as a scaffold for the initiation machinery to stimula
Externí odkaz:
https://doaj.org/article/4626adc229bd48dc902ff7c0880575dc
Autor:
Kibum Kim, Hee Chan Yoo, Byung Gyu Kim, Sulhee Kim, Yulseung Sung, Ina Yoon, Ya Chun Yu, Seung Joon Park, Jong Hyun Kim, Kyungjae Myung, Kwang Yeon Hwang, Sunghoon Kim, Jung Min Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1576ff3c4630415591a9b56d6f1725e9
Autor:
SungHoon Kim, Seongmin Cho, Sang Bum Kim, Youngjin Lee, Ee Chan Song, Uijoo Kim, Hyeong Yun Kim, Ji Hun Suh, Peter C Goughnour, YounHa Kim, Ina Yoon, Na Young Shin, Doyeun Kim, Il-Kyu Kim, Chang-Yuil Kang, Song Yee Jang, Myung Hee Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background The generation of antigen-specific cytotoxic T lymphocyte (CTL) responses is required for successful cancer vaccine therapy. In this regard, ligands of Toll-like receptors (TLRs) have been suggested to activate adaptive immune responses by
Externí odkaz:
https://doaj.org/article/86e4d178fe8d4592938b1225a02f36e8
Autor:
Jong Hyun Kim, Chulho Lee, Minji Lee, Haipeng Wang, Kibum Kim, Seung Joon Park, Ina Yoon, Jayun Jang, Hanchao Zhao, Hoi Kyoung Kim, Nam Hoon Kwon, Seung Jae Jeong, Hee Chan Yoo, Jae Hyun Kim, Jee Sun Yang, Myeong Youl Lee, Chang Woo Lee, Jieun Yun, Soo Jin Oh, Jong Soon Kang, Susan A. Martinis, Kwang Yeon Hwang, Min Guo, Gyoonhee Han, Jung Min Han, Sunghoon Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Leucyl-tRNA synthetase (LRS) is a leucine sensor of the mTORC1 pathway. Here, the authors identify inhibitors of the GTPase activating function of LRS, not affecting its catalytic activity, and demonstrate that the leucine sensor function of LRS can
Externí odkaz:
https://doaj.org/article/0d36499938674c89bf88e38b120784b7
Publikováno v:
Korean Business Education Review. 37:285-303
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70033770904a871fbf7f8b641ac056ce
https://doi.org/10.23839/kabe.2022.37.5.285
https://doi.org/10.23839/kabe.2022.37.5.285