Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Ina, Dix"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1246-1258 (2015)
The chemical behavior of various oligoenes 2 has been studied. The catalytic hydrogenation of diene 3 yielded monoene 4. Triene 7 was hydrogenated to diene 8, monoene 9 and saturated hydrocarbon 10. Bromine addition to 3 and 7 yielded the dibromides
Externí odkaz:
https://doaj.org/article/f3ac8cd0cccf4246a9067cbc640b82b0
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2013-2020 (2014)
Ethynyl[2.2]paracyclophanes are shown to be useful substrates for the preparation of complex, highly unsaturated carbon frameworks. Thus both the pseudo-geminal- 2 and the pseudo-ortho-diethynylcyclophane 4 can be dimerized by Glaser coupling to the
Externí odkaz:
https://doaj.org/article/6d368c409ca0493d92c7292621ff7133
Autor:
Youngah Shin, Moo Je Sung, Monish Jain, Jake Axford, Natalie Dales, Ina Dix, Brian Hurley, Lawrence G. Hamann, Karin Briner, Atwood K. Cheung, John I. Manchester, Donovan N. Chin, Rajeev Sivasankaran
Publikováno v:
Journal of Medicinal Chemistry. 64:4744-4761
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by low levels of functional survival motor neuron protein (SMN) resulting from a deletion or loss of function mutation of the survival motor neuron 1 (SMN1) gene. Branaplam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb500bf78e4fb0857bfdd9a64443fed
https://doi.org/10.1021/acs.jmedchem.0c02173
https://doi.org/10.1021/acs.jmedchem.0c02173
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1705-1712 (2013)
With the goal of eventually synthesizing [5]radialene (3), the still missing member of the parent radialene hydrocarbons, we have prepared the pentaacetates 21 and 31, the pentabromide 29 and the hexabromide 32. In principle these should be convertib
Externí odkaz:
https://doaj.org/article/379eccf4c42a4ff69793b3d62c60b5ec
Autor:
Marc Bigaud, Achim Schlapbach, Ina Dix, Ralf Endres, Jean Quancard, Jutta Blank, Frédéric Bornancin, Markus Wartmann, Julien Scesa, Paulo Antonio Fernandes Gomes Dos Santos, Eva Altmann, Thomas Radimerski, Guido Bold, Nicole Buschmann, Samu Melkko, Andreas Weiss, Paul W. Manley, P. Erbel, Oliver Simic, Thomas Zoller, Catherine H. Régnier, Ansgar Schuffenhauer, Elisabeth Buchdunger, Martin Renatus, Paul M.J. McSheehy, Carole Pissot Soldermann
Publikováno v:
Journal of Medicinal Chemistry. 63:14576-14593
MALT1 plays a central role in immune cell activation by transducing NF-κB signaling, and its proteolytic activity represents a key node for therapeutic intervention. Two cycles of scaffold morphing of a high-throughput biochemical screening hit resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9969a4c36550186a210fdfae8c1af415
https://doi.org/10.1021/acs.jmedchem.0c01245
https://doi.org/10.1021/acs.jmedchem.0c01245
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, Pp 932-937 (2010)
Four isomeric dialdehydes 4, readily available from cycloaddition of propiolic aldehyde (2) to 1,2,4,5-hexatetraene (1), were separated by chromatography and recrystallization, and were characterized by their spectroscopic data. The individual isomer
Externí odkaz:
https://doaj.org/article/c9e7848249f0492e8bca68a964aab7ca
Autor:
Jake, Axford, Moo Je, Sung, John, Manchester, Donovan, Chin, Monish, Jain, Youngah, Shin, Ina, Dix, Lawrence G, Hamann, Atwood K, Cheung, Rajeev, Sivasankaran, Karin, Briner, Natalie A, Dales, Brian, Hurley
Publikováno v:
Journal of medicinal chemistry. 64(8)
Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease caused by low levels of functional survival motor neuron protein (SMN) resulting from a deletion or loss of function mutation of the survival motor neuron 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13330dc0c7e19f69d4bd3cf1bf193353
https://pubmed.ncbi.nlm.nih.gov/33822618
https://pubmed.ncbi.nlm.nih.gov/33822618
Autor:
Carole, Pissot Soldermann, Oliver, Simic, Martin, Renatus, Paulus, Erbel, Samu, Melkko, Markus, Wartmann, Marc, Bigaud, Andreas, Weiss, Paul, McSheehy, Ralf, Endres, Paulo, Santos, Jutta, Blank, Ansgar, Schuffenhauer, Guido, Bold, Nicole, Buschmann, Thomas, Zoller, Eva, Altmann, Paul W, Manley, Ina, Dix, Elisabeth, Buchdunger, Julien, Scesa, Jean, Quancard, Achim, Schlapbach, Frédéric, Bornancin, Thomas, Radimerski, Catherine H, Régnier
Publikováno v:
Journal of medicinal chemistry. 63(23)
MALT1 plays a central role in immune cell activation by transducing NF-κB signaling, and its proteolytic activity represents a key node for therapeutic intervention. Two cycles of scaffold morphing of a high-throughput biochemical screening hit resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c9148f487b1a8d48b0cb731fa2d9337
https://pubmed.ncbi.nlm.nih.gov/33252239
https://pubmed.ncbi.nlm.nih.gov/33252239
Autor:
Roland Feifel, Philip C. Smith, Ursula Bodendorf, Robert Epple, Philippe Couttet, Reiner Aichholz, Danilo Guerini, Ina Dix, Ben Wen, Bo Liu, Peter Wipfli, Juraj Velcicky, Toni Widmer, Trixi Brandl, Daniel R. Beisner, Pascal Rigollier
Publikováno v:
Journal of Medicinal Chemistry. 61:865-880
Signal peptide peptidase-like 2a (SPPL2a) is an aspartic intramembrane protease which has recently been shown to play an important role in the development and function of antigen presenting cells such as B lymphocytes and dendritic cells. In this pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f019f401a7282949702f439bc69e4e37
https://doi.org/10.1021/acs.jmedchem.7b01371
https://doi.org/10.1021/acs.jmedchem.7b01371
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 6, Pp i46-i47 (2009)
The title compound, pentastrontium tris[pentafluoridooxidovanadate(IV)] fluoride trihydrate, was obtained under hydrothermal conditions. Its crystal structure has been refined from intensity data of a non-merohedrally twinned crystal. Two domains in
Externí odkaz:
https://doaj.org/article/42955191f3f74b87bc620464c38afc44