Zobrazeno 1 - 4
of 4
pro vyhledávání: '"InWook Park"'
Autor:
Jusung An, Kyeonghwan Kim, Ho Jae Lim, Hye Yun Kim, Jinwoo Shin, InWook Park, Illhwan Cho, Hyeong Yun Kim, Sunghoon Kim, Catriona McLean, Kyu Yeong Choi, YoungSoo Kim, Kun Ho Lee, Jong Seung Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Amyloid-β (Aβ) oligomers are implicated in the onset of Alzheimer’s disease (AD). Herein, quinoline-derived half-curcumin-dioxaborine (Q-OB) fluorescent probe was designed for detecting Aβ oligomers by finely tailoring the hydrophobicit
Externí odkaz:
https://doaj.org/article/b0629641da734999a8efef9bc1a0e7dc
Autor:
A-Hyeon Lee, Sung-Chul Hong, Inwook Park, Soljee Yoon, YoungSoo Kim, Jinsik Kim, Seung-Hoon Yang
Publikováno v:
Applied Sciences, Vol 11, Iss 13, p 5878 (2021)
The visualization of misfolded Aβ peptides by using fluorescence chemical dyes is very important in Alzheimer’s disease (AD) diagnosis. Here, we describe the fluorescent substance, fucoxanthin, which detects Aβ aggregates in the brain of AD trans
Externí odkaz:
https://doaj.org/article/1f02009e7258414c993325d2ebbdd4dc
Autor:
Jusung An, Kyeonghwan Kim, Ho Jae Lim, Jinwoo Shin, InWook Park, Illhwan Cho, Hyeong Yun Kim, Sunghoon Kim, YoungSoo Kim, Kun Ho Lee, Jong Seung Kim
Amyloid-β oligomers (oAβ) are implicated in the onset of Alzheimer’s disease (AD). Herein, quinoline-derived half-curcumin-dioxaborine (Q-OB), a highly selective and sensitive fluorescent probe, was designed for detecting oAβ by finely tailoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd8b42c66687c2b168619c5ab9d821fa
https://doi.org/10.21203/rs.3.rs-2712380/v1
https://doi.org/10.21203/rs.3.rs-2712380/v1
Autor:
Hee Yang Lee, Seungyeop Baek, Minhae Cha, Seung‐Hoon Yang, Illhwan Cho, Heewon Shin, Sejin Lee, Hye Yun Kim, Songmin Lee, Jisu Shin, Donghee Lee, Kyeonghwan Kim, InWook Park, Soljee Yoon, Jiyoon Kim, Seong Jeong Park, Seong Muk Kim, Ko Eun Kim, Hye Ju Kim, Min‐Seok Oh, Gwan‐Ho Lee, Byung‐Yong Yu, Priyadharshini Kannan, Keunwan Park, YoungSoo Kim
Publikováno v:
Angewandte Chemie (International ed. in English).
Amyloid-β (Aβ) in the form of neurotoxic aggregates is regarded as the main pathological initiator and key therapeutic target of Alzheimer's disease. However, anti-Aβ drug development has been impeded by the lack of a target needed for structure-b