Zobrazeno 1 - 10
of 1 014
pro vyhledávání: '"In-Young Cha"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 15-24 (2024)
ABSTRACTGlucose transporter 5 (GLUT5), the main fructose transporter in mammals, is primarily responsible for absorbing dietary fructose in the small intestine. The expression of this intestinal gene significantly increases in response to development
Externí odkaz:
https://doaj.org/article/c7122540d11f487bb98a9cdc28cb8c31
Autor:
Nam-Hee Kim, Seung-Jin Lee, Kyeong-Jin Lee, Ae Ri Song, Hyun-Je Park, Jong Soo Kang, Joo Young Cha, Yong-Hyun Han
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5881-5893 (2024)
Nonalcoholic steatohepatitis (NASH) is characterized by severe inflammation and fibrosis due to an excessive accumulation of triglycerides (TGs) in the liver with a dysregulated de novo lipogenesis (DNL) pathway. In this study, we aimed to evaluate t
Externí odkaz:
https://doaj.org/article/20f531cdf7b041219e8a334694103c61
Autor:
Hwa-Young Yu, Kyoung Kon Kim, Sin Hwa Baek, Cho I Park, Hye Jin Jeon, Ae Ri Song, Hyun-Je Park, Il Bum Park, Jong Soo Kang, Jung Min Kim, Tae Woo Kim, Sun Min Jang, Joo Young Cha, Junghyun Kim
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1437-1450 (2024)
Obesity is one of the major risk factors for metabolic diseases worldwide. This study examined the effects of YC-1102, an extract derived from the roots of Rosa multiflora, on 3T3-L1 preadipocytes and high-fat diet (HFD)-induced obese mice. In vivo e
Externí odkaz:
https://doaj.org/article/8ffedcbb96d14c15b1d5e4f425b723e1
Autor:
Eunkyeong Jang, ChangYeon Kim, Jeonghyun Noh, Hansol Yi, Sungsin Jo, Jin-Sil Park, Woochang Hwang, Ji-Young Cha, Mi-La Cho, Tae-Hwan Kim, Jeehee Youn
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114878- (2024)
Summary: The transcription repressor Bach2 plays a crucial role in shaping humoral immunity, but its cell-autonomous function remains elusive. Here, we reveal the mechanism by which Bach2 regulates effector cell maturation in peripheral B cells. In r
Externí odkaz:
https://doaj.org/article/6a860a8f9487444a8b232efaedba224c
Publikováno v:
IEEE Journal of the Electron Devices Society, Vol 12, Pp 581-586 (2024)
In this work, we investigated the instability of threshold voltage (Vth) in p-GaN/AlGaN/GaN high electron mobility transistors (HEMTs) under positive gate biases and high temperatures. We reveal an abnormal temperature dependence of threshold voltage
Externí odkaz:
https://doaj.org/article/ab1ad5f573de4b1e8a372aaca85675e0
Autor:
Woori Kim, Mohit Tripathi, Chunhyung Kim, Satyapavan Vardhineni, Young Cha, Shamseer Kulangara Kandi, Melissa Feitosa, Rohit Kholiya, Eric Sah, Anuj Thakur, Yehan Kim, Sanghyeok Ko, Kaiya Bhatia, Sunny Manohar, Young-Bin Kong, Gagandeep Sindhu, Yoon-Seong Kim, Bruce Cohen, Diwan S. Rawat, Kwang-Soo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaqu
Externí odkaz:
https://doaj.org/article/b81b0d3dcdc14cc4b8e8e7f126ca1dbb
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2939 (2024)
Programmed death ligand 1 (PD-L1) plays a pivotal role in cancer immune evasion and is a critical target for cancer immunotherapy. This review focuses on the regulation of PD-L1 through the dynamic processes of ubiquitination and deubiquitination, wh
Externí odkaz:
https://doaj.org/article/ca13a6c854e946fe95ec3c17d1b5887b
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1276 (2024)
Fibrosis, characterized by excessive extracellular matrix accumulation, disrupts normal tissue architecture, causes organ dysfunction, and contributes to numerous chronic diseases. This review focuses on Krüppel-like factor 10 (KLF10), a transcripti
Externí odkaz:
https://doaj.org/article/46ca4557c6c045929630534038e92a5f
Publikováno v:
Korean Journal of Clinical Oncology, Vol 18, Iss 1, Pp 1-10 (2022)
Purpose Apurinic/apyrimidinic endonuclease 1 (APE1) is a key enzyme involved in the base excision repair pathway. It also has redox activity and maintains various transcription factors in an active reduced state. APE1 may be associated with chemoresi
Externí odkaz:
https://doaj.org/article/1ab0b3431f134bba8e4f43d0d65437a4
Publikováno v:
Journal of Electromagnetic Engineering and Science, Vol 22, Iss 3, Pp 291-295 (2022)
In this work, we report hot carrier-induced degradation in normally-on AlGaN/GaN high electron mobility transistors (HEMTs) with a 0.25-μm gate. To analyze the hot carrier effect, the semi-on state stress test was carried out and the DC and pulsed I
Externí odkaz:
https://doaj.org/article/22e6468f564e414d97ed8f361d151ec5