Zobrazeno 1 - 10
of 18
pro vyhledávání: '"In-Fah M Lee"'
Autor:
Silke S Zakrzewski, Jan F Richter, Susanne M Krug, Britta Jebautzke, In-Fah M Lee, Juliane Rieger, Monika Sachtleben, Angelika Bondzio, Jörg D Schulzke, Michael Fromm, Dorothee Günzel
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79643 (2013)
Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage. The porcine jejunal cell line IPEC-J2 i
Externí odkaz:
https://doaj.org/article/16ba4617e0394c8081afad0bee7a5681
Autor:
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Cells, Vol 12, Iss 24, p 2846 (2023)
Background: In patients with diarrhea-predominant irritable bowel syndrome (IBS-D), the diarrheal mechanisms are largely unknown, and they were examined in this study on colon biopsies. Methods: Electrophysiological measurements were used for monitor
Externí odkaz:
https://doaj.org/article/617ff395507043f5b1568681be88f5b2
Autor:
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Cells, Vol 12, Iss 2, p 236 (2023)
Background: The underlying pathophysiology of irritable bowel syndrome (IBS) is still unclear. Our aim was to investigate the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type IBS (IBS-M). Methods: Colonoscopic
Externí odkaz:
https://doaj.org/article/6dc6f099552e46198939f9832ba91002
Autor:
Caroline Hempel, Dorothee Günzel, Gerd Krause, T. Saleh, Anna Piontek, Jonas Protze, B. Riebe, Jörg Piontek, E. Altun, In-Fah M. Lee, Anja Fromm
Publikováno v:
Journal of Molecular Biology. 432:2405-2427
Tight junctions regulate paracellular permeability size and charge selectively. Models have been proposed for the molecular architecture of tight junction strands and paracellular channels. However, they are not fully consistent with experimental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4cd44e7d9c63a0a942125838198564
https://doi.org/10.1016/j.jmb.2020.02.034
https://doi.org/10.1016/j.jmb.2020.02.034
Autor:
Anja Fromm, Michael Fromm, In-Fah M. Lee, Jörg-Dieter Schulzke, Petra Dames, Turner, Jan F. Richter, Susanne M. Krug, Christian Bojarski
Publikováno v:
Mucosal immunology
In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn’s disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e2f88b80da01360cd6423288866fc1
https://doi.org/10.1038/mi.2017.52
https://doi.org/10.1038/mi.2017.52
Autor:
Anja Fromm, Susanne Milatz, Luca Meoli, Caroline Hempel, Jörg Piontek, Rukeia El-Athman, Dorothee Günzel, In-Fah M. Lee, Christoph Grohe
Publikováno v:
Annals of the New York Academy of Sciences. 1405:102-115
Claudins are integral components of tight junctions (TJs) in epithelia and endothelia. When expressed in cell lines devoid of TJs, claudins are able to form TJ-like strands at contacts between adjacent cells. According to a current model of TJ strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01b7140bb80e3aff822b5e3364e04548
https://doi.org/10.1111/nyas.13393
https://doi.org/10.1111/nyas.13393
Publikováno v:
Molecular Nutrition & Food Research. 60:2576-2586
cope Anti-inflammatory properties of the ginger-derived pungent component 6-shogaol (6-SG) have been studied intensively in recent years. Purpose of this study was to characterize the influence of 6-SG on inflammation-related intestinal barrier dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e15efa9d2ea0054e1abc1219c4146fe
https://doi.org/10.1002/mnfr.201600274
https://doi.org/10.1002/mnfr.201600274
Autor:
In-Fah M. Lee, Susanne M. Krug, Franziska Weiß, Jia-Chen E. Hu, Jörg D. Schulzke, Michael Fromm
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d806279a4be3f9ed9d5e116a941d3ec
https://doi.org/10.1096/fasebj.2020.34.s1.03855
https://doi.org/10.1096/fasebj.2020.34.s1.03855
Autor:
Jia-Chen E. Hu, Anja Fromm, Michael Fromm, In-Fah M. Lee, Susanne M. Krug, Joerg-Dieter Schulzke, Franziska Weiß, Tilman Breiderhoff
Publikováno v:
Journal of Crohn's and Colitis. 14:S137-S137
Background In Inflammatory bowel disease, intestinal homeostasis cannot be sustained due to an overreaction of the immune system and a disturbed epithelial barrier due to an impaired tight junction (TJ). At tricellular TJs (tTJs), which are formed wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608d40225021add7b46dad4f8a4e936e
https://doi.org/10.1093/ecco-jcc/jjz203.144
https://doi.org/10.1093/ecco-jcc/jjz203.144
Autor:
Jörg D. Schulzke, Roland Bücker, Annette Moter, Anja Fromm, In-Fah M. Lee, Judith Kikhney, Nina A. Hering
Publikováno v:
Journal of Infectious Diseases. 213:1157-1162
Infection with Yersinia enterocolitica causes acute diarrhea in early childhood. A mouse infection model presents new findings on pathological mechanisms in the colon. Symptoms involve diarrhea with watery feces and weight loss that have their functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472722b9ac6b82e91c2324b83c7ef098
https://doi.org/10.1093/infdis/jiv571
https://doi.org/10.1093/infdis/jiv571