Zobrazeno 1 - 10
of 847
pro vyhledávání: '"In vivo antitumor"'
Autor:
Rasha A. Hamza, Islam Mostafa, Yasmin S. Mohamed, Gamal A. Dora, Abdel-Monem Ateya, Mahmoud Abdelaal, Omer I. Fantoukh, Abdulaziz Alqahtani, Rasha A. Attia
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 1, Pp 125-134 (2023)
Hepatocellular carcinoma (HCC) is one of the leading causes of mortality worldwide; therefore, searching for an effective treatment for this illness is of great importance. In the present work, in vitro cytotoxic activity of the ethanol extract of th
Externí odkaz:
https://doaj.org/article/1459b7ee98924886a65f8ea77bfc28d7
Autor:
Kamel Chettab, Chantel Fitzsimmons, Alexey Novikov, Morgane Denis, Capucine Phelip, Doriane Mathé, Pierre Antoine Choffour, Sabine Beaumel, Eric Fourmaux, Patrick Norca, David Kryza, Anne Evesque, Lars Petter Jordheim, Emeline Perrial, Eva-Laure Matera, Martine Caroff, Jerome Kerzerho, Charles Dumontet
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bacterial lipopolysaccharides (LPS) are potent innate immunostimulants targeting the Toll-like receptor 4 (TLR4), an attractive and validated target for immunostimulation in cancer therapy. Although LPS possess anti-tumor activity, toxicity issues pr
Externí odkaz:
https://doaj.org/article/117d1de624a6452abc1b619b93a387d8
Autor:
Ildikó Szabó, Beáta Biri-Kovács, Balázs Vári, Ivan Ranđelović, Diána Vári-Mező, Éva Juhász, Gábor Halmos, Szilvia Bősze, József Tóvári, Gábor Mező
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1095 (2024)
Malignant melanoma is one of the most aggressive and resistant tumor types, with high metastatic properties. Because of the lack of suitable chemotherapeutic agents for treatment, the 5-year survival rate of melanoma patients with regional and distan
Externí odkaz:
https://doaj.org/article/0682fb640e5e4aa18e97754831fcece1
Akademický článek
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Autor:
Shan Xu, Xin Sun, Leixuan Luo, Yang Yang, Qiuyan Guo, Sheng Tang, Zhiyan Jiang, Yuzhen Li, Jiaqian Han, Wenhui Gan, Feiyi Yang, Xuan Zhang, Yijun Liu, Chuanchuan Sun, Jie He, Meng Liu, Daiying Zuo, Wufu Zhu, Yingliang Wu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113537- (2022)
Breast cancer has become the most commonly diagnosed cancer, surpassing lung cancer, with 2.26 million new breast cancers worldwide in 2020. Hence, there is an urgent need to develop effective molecularly targeted therapeutic drugs to treat breast ca
Externí odkaz:
https://doaj.org/article/fefec4ccb42946699ef2c27b7c718346
Autor:
Shipeng He, Junhui Ma, Yuxin Fang, Ying Liu, Shanchao Wu, Guoqiang Dong, Wei Wang, Chunquan Sheng
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1617-1628 (2021)
The dose-related adverse effects of MDM2‒P53 inhibitors have caused significant concern in the development of clinical safe anticancer agents. Herein we report an unprecedented homo-PROTAC strategy for more effective disruption of MDM2‒P53 intera
Externí odkaz:
https://doaj.org/article/8d5578435fec442c91e420b01787c6aa
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 569-579 (2021)
We report the formulation of nanoassemblies (NAs) comprising C225 conjugates Gd-PFH-NAs (C-Gd-PFH-NAs) for low-intensity focused ultrasound diagnosis ablation of thyroid cancer. C-Gd-PFH-NAs showed excellent stability in water, phosphate-buffered sal
Externí odkaz:
https://doaj.org/article/d165dc4152a94543b0cb2d4682722fa8
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 776-786 (2021)
Cancers continue to be the second leading cause of death worldwide. Despite the development and improvement of surgery, chemotherapy, and radiotherapy in cancer management, effective tumor ablation strategies are still in need due to high cancer pati
Externí odkaz:
https://doaj.org/article/c4725ebf79a549458d4a60a6df81b7e2
Autor:
Zhe Zhou
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 1319-1328 (2020)
Cancers continue to be the second leading cause of death worldwide. Despite the development and improvement of surgery, chemotherapy and radiotherapy in cancer management, effective tumor ablation strategies are still in need due to high cancer patie
Externí odkaz:
https://doaj.org/article/33a1aeee81da4be9ad03525afb594427
Akademický článek
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