Eco-Friendly Extraction of Green Coffee Oil for Industrial Applications: Its Antioxidant, Cytotoxic, Clonogenic, and Wound Healing Properties

Autor: Lucas D. Dias, Fernanda Mansano Carbinatto, Isabelle da Silveira Almeida, Kate C. Blanco, Franciane Marquele-Oliveira, Carla Carolina Munari, Vanderlei Salvador Bagnato

Publikováno v: Fermentation, Vol 9, Iss 4, p 370 (2023)

The development of natural oil-based cosmetic and pharmaceutical products presents great scientific and commercial interest. Herein, we aimed to extract green coffee oil from Arabic coffee by a sustainable cold-pressing method. Furthermore, this work

Externí odkaz: https://doaj.org/article/8daf98951de04f029ff99e29ab1929ee

Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound

Autor: Bruno Pagano, Erica Salvati, Simona Marzano, Stefano De Tito, Eleonora Vertecchi, Jussara Amato, Anna Di Porzio, Nunzia Iaccarino, Antonio Randazzo

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10315, p 10315 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19

DNA G-quadruplex (G4) structures, either within gene promoter sequences or at telomeres, have been extensively investigated as potential small-molecule therapeutic targets. However, although G4s forming at the telomeric DNA have been extensively inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f20cfa33c2d6415fc14d7a244f853ab
https://www.mdpi.com/1422-0067/22/19/10315

Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives

Autor: Emanuele Ugo Garzarella, Sonia Di Gaetano, Nunzia Iaccarino, Domenica Capasso, Anna M. Ogloblina, Marianna G. Yakubovskaya, Bruno Pagano, Nina G. Dolinnaya, Jussara Amato, Antonio Randazzo

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7781, p 7781 (2020)
Volume 21
Issue 20

Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are known to bind to nucleolin protein, resulting in the inhibition of nucleolin-mediated phenomen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219459436c6b6a4e9d12a54598ca920a
http://europepmc.org/articles/PMC7590035

Human exposure to endocrine disruptors by inhalation : characterization of indoor air contamination by chemical and in vitro biological analyses

Autor: Laborie, Stéphanie

Publikováno v: Santé. École pratique des hautes études-EPHE PARIS, 2015. Français. ⟨NNT : 2015EPHE3059⟩

The objective of this project was to develop a bio-analytical approach leading to the assessment of the inherent hazard of the indoor air multi-contamination. Chromatographic methods combined with mass spectrometry were developed and validated for 62

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3f478124e8ed883e90c6f82051c35018
https://tel.archives-ouvertes.fr/tel-02099667