Zobrazeno 1 - 10
of 2 226
pro vyhledávání: '"In situ gel"'
Autor:
Swati P. Barangule, Avish D. Maru
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 5, Pp 102-115 (2024)
Background: Luffa acutangula has good anti-inflammatory and antioxidant activity. Ulcerative colitis has inflamed intestinal mucosal lining with frequent diarrhoea, mucosal, and bloody stools. The rectal administration provides high bioavailability,
Externí odkaz:
https://doaj.org/article/215f092c322847c7877a47e21a7f3c9b
Autor:
Omar M. Alwan, Iman S. Jaafar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Limited solubility is the main cause of the low local availability of anti-candidiasis drug, miconazole nitrate (MN). The study’s objective was to develop and characterize microemulsion (ME) based temperature-triggered in situ gel of MN fo
Externí odkaz:
https://doaj.org/article/2eef495b1c364867a0b7c4e1db3a8c63
Autor:
Insan Sunan Kurniawansyah, Taofik Rusdiana, Insi Farisa Desy Arya, Handrian Ramoko, Habibah A. Wahab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The primary goal was to enhance the stability and bioavailability of chloramphenicol for ophthalmic use without compromising patient comfort, such as causing blurry vision. This study employed a 2-level full factorial design to optimize the
Externí odkaz:
https://doaj.org/article/9e2fb62a41824c6c9bb8c0093464d893
Publikováno v:
المجلة العراقية للصيدلة, Vol 21, Iss 3, Pp 89-101 (2024)
Background: Periodontitis is a chronic and potentially severe inflammatory disease that can affect both men and women. It is caused by various factors such as inadequate oral health, stress, consumption of alcoholic beverages, cigarette smoking, foo
Externí odkaz:
https://doaj.org/article/1f821ee761004f41827664064f93b111
Autor:
Ye, Zixuan, Zhou, Li, Luo, Xia, Xue, Kaifei, Liang, Lizhen, Meng, Zihui, Zhu, Pengrong, Li, Yanan ⁎, Huang, He ⁎
Publikováno v:
In Chemical Engineering Journal 1 February 2025 505
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 25, Iss 1 (2025)
Drug delivery to ocular tissues is challenging due to the rapid removal of instilled drugs due to the low resident time in ocular tissues. The study aimed to formulate an ophthalmic in situ gel that delivers two drugs (betamethasone sodium phosphate
Externí odkaz:
https://doaj.org/article/eacbe24e21fc44918fc07c2aace82c6d
Publikováno v:
The Iraqi Journal of Veterinary Medicine, Vol 48, Iss 2 (2024)
Conventional ocular drug delivery forms (eye drops, eye ointments, and eye gels) possess poor bioavailability, less retention, and rapid precorneal discharge. In veterinary medicine, treating eye infections in animals like rabbits, dogs, and cats pos
Externí odkaz:
https://doaj.org/article/243e5854d8554e14afb0f01d649bb5d8
Autor:
Mohamed M. Badran, Areej Alsubaie, Mounir M. Salem Bekhit, Abdullah H. Alomrani, Aliyah Almomen, Mohamed Abbas Ibrahim, Doaa Hasan Alshora
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 12, Pp 102208- (2024)
Itraconazole (ITZ) is a highly effective antifungal agent. However, its oral application is associated with systemic toxicity and poor topical use. The present study aims to improve the antifungal activity of ITZ by loading it into bioadhesive niosom
Externí odkaz:
https://doaj.org/article/392b1667cff34c2cb9e4e5ff5b70074f
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
The application of ketoconazole (KET) in ocular drug delivery is restricted by its poor aqueous solubility though its broad-spectrum antifungal activity. The aim of this study is to develop an ion-sensitive in situ gel (ISG) of KET to promote its ocu
Externí odkaz:
https://doaj.org/article/a6661559ca6046229fb77cb264057066
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Sirolimus (SR) is a macrolide with antifungal and antitumor immunosuppressant properties, classified as a selective inhibitor of mammalian target of rapamycin (mTOR). In this study, an ionic in situ gel of SR (SR-SUS-ISG) was formulated usin
Externí odkaz:
https://doaj.org/article/3aaa1d4c4eb649e492e70d6f832c8471